Method for extracting high-purity rutin with flash-extraction technology

Abstract

The invention discloses a method for extracting high-purity rutin with a flash-extraction technology, which comprises the following steps of: first, putting sophora flower bud into a container, adding carbinol, putting the container on a Chinese medicine extraction device, extracting the sophora flower bud by grinding, and filtering to obtain filter liquor; second, after the filter liquor is concentrated by using conventional concentrate equipment, recycling the carbinol to obtain a rutin crude extract; third, completely dissolving the crude extract with the carbinol, adding 80 DEG C purifiedwater for stirring, and then naturally decreasing temperature to the moment that the rutin is recrystallized out; and fourth, filtering and drying the crystal so as to obtain a rutin finished product. The method has the advantages that as equipment for extracting active components of Chinese medicine, namely a flash type extractor is applied in the method for extracting rutin, the extracting timeis greatly shortened, and the whole process is simple and is easy to operate. A mixed solvent is not used, the solvent is easily recycled, the cost is low, and the method is beneficial to environmental protection. The yield and the purity of the obtained rutin are high and can reach the quality standard of national pharmacopoeia and European Pharmacopoeia EP 6.

Description

technical field [0001] The invention relates to a method for extracting rutin, in particular to a method for extracting high-purity rutin using a flash extraction technique. Background technique [0002] Rutin is a glycoside synthesized by the dehydration of the hydroxyl group at the 3-position of Quercetin and Rutinose (a disaccharide composed of Glucose and Rhamnose). Rutin widely exists in the plant kingdom, and at least 70 kinds of plants containing rutin have been found, such as tobacco leaves, Sophora japonica, buckwheat and dandelion. In particular, Sophora japonica (the unopened flower bud of the plant Sophora japonica) and buckwheat have the highest content, which can be used as raw materials for extracting a large amount of rutin. Rutin is light yellow powder or very fine needle-like crystals, containing three molecules of crystal water, with a melting point of 174~178°C and anhydrous 188~190°C. Solubility: 1:10000 in cold water; 1:200 in hot water; 1:650 in cold...

AI Technical Summary

Problems solved by technology

Because this method uses a large amount of mixed solvents, although the yield is higher than that of the traditional method, the mixed solvents are not easy to separate, resulting in a substantial increase in production costs; the recovery and reuse of mixed solvents is a very complicated technical problem

And the whole method is complicated to operate, will bring the loss of a large amount of organic solvents and environmental pollution, and investment equipment is too much, and production cycle is long, is not suitable for promoting