Anti-hepatitis natural medicine compound preparation, preparation method and application thereof
A technology of natural medicines and compound preparations, applied in biochemical equipment and methods, methods based on microorganisms, pharmaceutical formulations, etc., can solve the problems of unseen research reports on compound preparations of licorice and spirulina, difficulty in releasing intracellular proteins, and inability to destroy the helix Algae and other problems, to achieve good application prospects, excellent curative effect, improve the effect of oral bioavailability
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[0056] Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings.
[0057] The licorice used in the preferred embodiment is the wild Glycyrrhiza officinalis in Hangjin Banner, Inner Mongolia, and the spirulina used is the food-grade spirulina powder (average particle size 150-250 μm) produced by Shandong Wudi First Bioengineering Company.
[0058] One, preparation technology research and process condition optimization of compound preparation of the present invention
[0059] 1. The effect of physical pulverization on the yield of glycyrrhizic acid
[0060] Considering that the main reason for the poor yield of glycyrrhizic acid in the existing extraction methods is that the lignin and cellulose rich in licorice have a structural barrier effect on the dissolution of glycyrrhizic acid, the present invention successively adopts mechanical crushing, high-pressure steam explosion crushing, and airflow crushin...
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