Method for separating and preparing alpha-terthienyl, thianthrene and p-terphenyl

Abstract

The invention relates to a method for separating and preparing high-purity monomers of alpha-terthienyl, thianthrene and p-terphenyl from plant flaveria bidentis extracts, obtained by petroleum ether refluxing, with high-speed countercurrent chromatography. In the method, the countercurrent chromatography is adopted to separate and prepare the high-purity alpha-terthienyl, thianthrene and p-terphenyl from the plant flaveria bidentis extracts, obtained by petroleum ether refluxing, a solvent comprises three components including petroleum ether or n-alkane, dichloromethane and acetonitrile or fatty alcohol in the volume ratio of 10:(0-3):(12-7); and the method is suitable for separation and preparation of the monomers of alpha-terthienyl, thianthrene and p-terphenyl through various models of countercurrent chromatographs, so that a large amount of crude products or synthetic mixtures can be directly fed, the purity of separated alpha-terthienyl is over 99%, and the purity of thianthrene and p-terphenyl can reach more than 90%.

Description

technical field

[0001] The invention relates to a preparation and separation method for separating and preparing high-purity monomers α-terthiophene, thianthracene and p-terphenyl from the extract of alien invasive plant chrysanthemum chrysanthemum by high-speed countercurrent chromatography. Background technique

[0002] Chrysanthemum [ Flaveria bidentis (L.) Kuntze] is the genus Chrysanthemum chrysanthemum (L.) Flaveria ) annual herb originating from South America. Chrysanthemum chrysanthemum plants are tall and dense, with amazing seed yield, strong reproductive ability and adaptability. It can invade various habitats such as farmland, roadside, and wasteland, and can inhibit the growth of other plants through allelopathy, thereby quickly occupying ecological niches. In addition to its origin, Chrysanthemum chrysanthemum is invasive in other countries and regions, posing a great threat to the ecological environment and agricultural production, and is a highly dangerou...