Extract for treating pharyngolaryngitis and preparation method thereof
What is Al technical title?
Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
An extract and a technique for pharyngitis, which are applied in the field of extracts for treating pharyngitis and their preparation, can solve problems such as loss of volatile active components, and achieve the effects of significant effect, improved practicability and high extraction rate
Active Publication Date: 2011-09-21
SHENZHEN NEPTUNUS PHARM CO LTD
View PDF1 Cites 6 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
Solve the problem of large loss of volatile active ingredients in the direct water ext
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Image
Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
Click on the blue label to locate the original text in one second.
Reading with bidirectional positioning of images and text.
Smart Image
Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0028] Preparation of Example 1 "Anti-pharyngitis" Extract
[0029] Take 2 kg of Nepeta Nepeta, 8 kg of Platycodon grandiflorum, and 4 kg of raw licorice, and dry them at 40°C for 3 hours; crush the medicinal materials to a particle size of about 200 mesh. Then add 0.4 kg of methanol as an entraining agent, and extract in the separation tank of supercritical carbon dioxide extraction. The stage decompression separation pressure is 5Mpa, and the temperature is 35°C. The extract was collected as sample 1.
[0030] The outstanding advantages of this process technology are: (1) high extraction efficiency; (2) effectively enriching the main active ingredients, especially for terpenoids, etc. Basically, a large amount of such ingredients are lost, so that the application effect of the main drug is limited, and the volume of the extract is small, which improves the internal quality of traditional Chinese medicine; (3) fully removes impurities such as its polysaccharides; (4) reduce...
Embodiment 2
[0031] Preparation of Example 2 "Anti-pharyngitis" Extract
[0032] Take 2 kg of Nepeta Nepeta, 8 kg of Platycodon grandiflorum, and 4 kg of raw licorice, and dry them at a temperature of 60°C for 3 hours; grind the medicinal materials to a particle size of about 60 mesh. Put the dry powder in the extraction tank, add 15 kg of ethanol as an entrainer, and perform the first-stage decompression separation in the separation tank of supercritical carbon dioxide extraction. The pressure is 10Mpa and the temperature is 60°C; ℃. The extract was collected as sample 2.
Embodiment 3
[0033] Example 3 "Schizonepeta Soup" is prepared according to the traditional method recorded in ancient prescriptions
[0034] Take 2 kg of Nepeta Nepeta, 8 kg of Platycodon grandiflorum, and 4 kg of raw licorice, according to the traditional preparation method: add water, heat and reflux to extract twice, and concentrate the extract into a dry extract, which is used as sample 3. For comparison of samples 1 and 2.
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Login to view more
Abstract
The invention discloses an extract for treating pharyngolaryngitis. Medicinal materials such as 1 part of fine-leaf schizonepeta herb, 4 parts of platycodon root and 2 parts of raw liquorice are prepared by weight. The extract is prepared by the following steps of: 1) drying the medicinal materials, wherein the drying temperature is 40 to 60 DEG C, and the drying time is 3 to 4 hours; 2) crushing the medicinal materials into coarse powder; 3) filling the medicinal materials into a supercritical extraction tank, adding ethanol or methanol serving as an entrainer, and performing extraction for 3 to 4 hours under the conditions that the pressure is 5 to 10MPa, the temperature is 40 to 60 DEG C and the flow is 15 to 20L/h in the primary reduced pressure separation, and the pressure is 5 to 10MPa and the temperature is 35 to 50 DEG C in the secondary reduced pressure separation; and 4) dehydrating and drying the extract. By the supercritical preparation process, flavone, saponin and terpene components can be effectively enriched. The extract is characterized by comprising the following components in percentage by weight: more than or equal to 2.8 percent of glycyrrhizinic acid, more than or equal to 0.7 percent of liquiritin, more than or equal to 0.3 percent of platycodon D and 0.04 percent of menthone. The extract has anti-inflammatory and analgesic effects, and has more remarkable curative effect; and the preparation process is simple, the extraction rate is high, and the cost is low.
Description
technical field [0001] The present invention relates to an extract for treating pharyngitis and a preparation method thereof, in particular to an extract of a classic traditional Chinese medicine compound "Jiejie Decoction" and a preparation method thereof, and the use of the extract in the preparation of medicines for preventing and / or treating pharyngitis Applications. Background technique [0002] Pharyngitis belongs to the category of "throat numbness" in Chinese medicine. Modern medicine believes that it is an acute inflammation of the pharyngeal mucosa caused by pathogenic bacteria such as hemolytic streptococcus, staphylococcus, and pneumococcus. Traditional Chinese medicine believes that it is mostly caused by heat and evil poison that invades the throat, internally injures the lungs, and fights each other, causing throat swelling and pain; . The main clinical manifestations are pharyngeal redness, pain, dry itching, discomfort and foreign body sensation, often ac...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.
Login to view more 
Login to view more