Preparation method of hydroxypropyl trimethyl ammonium chloride chitin fiber

Abstract

The invention relates to a preparation method of hydroxypropyl trimethyl ammonium chloride chitin fiber, which belongs to the field of fiber material preparation. The preparation method is characterized in that quaternary ammonium salt groups are introduced onto chitin fiber molecular chains through the ring opening reaction between the amino groups on the chitin molecular chains and epoxy groupson 2, 3-epoxypropyl trimethyl ammonium chloride molecules, so the polycation characteristic of the chitin fiber is enhanced, and the antibacterial property of the chitin fiber is improved. The goal of maintaining the substituting degree of the hydroxypropyl trimethyl ammonium chloride chitin fiber to be in a range being 4 to 80 percent is realized through controlling the reaction conditions and the mol ratio of the glucosamine residue of the chitin fiber to the epoxypropyl trimethyl ammonium chloride, so the chitin fiber after the reaction has high antibacterial property, a large amount of liquid can also be absorbed, the basic form of the fiber can still be maintained after the liquid absorption, and the liquid absorption performance of the chitin fiber is enhanced. The preparation method of hydroxypropyl trimethyl ammonium chloride chitin fiber is simple, the cost is low, and the industrial production is easy to realize.

Description

Technical field [0001] The invention relates to a preparation method of antibacterial hydration chitosan fiber, in particular to a preparation method of hydroxypropyltrimethylammonium chloride chitosan fiber, which belongs to the field of fiber material preparation. Background technique [0002] Chitin is a renewable resource with reserves second only to cellulose on the earth. Its deacetylated derivative, chitosan, has good biocompatibility, biodegradability, hemostasis, and promotion of wound healing. Absorbable surgical sutures, wound dressings, drug carrier materials, artificial skin and other tissue engineering scaffold materials have broad application prospects. [0003] The chitosan is dissolved in an organic acid or an inorganic acid to form a viscous colloid. After coagulation and dehydration, chitosan fibers can be prepared, which are used to prepare wound dressings. Japanese Patent Publication (JP 60,059,123, 1985), Chinese Patent Publication No. CN1129748, publication ...

AI Technical Summary

Problems solved by technology

However, these modification methods, on the one hand, the position of the reaction substituent is uncertain, which makes the product more complicated, and the distribution of the substituent has an uncertain impact on its liquid absorption; Carrying out on the amino group of the molecular chain, so as to reduce the content of the amino group, resulting in further weakening of the antibacterial properties of the chitosan fiber

These problems will greatly limit the clinical application of dressings prepared from chitosan fibers, especially for burns and chronic wounds.

Images