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Traditional Chinese medicine composition used for treating high-pathogenicity porcine reproductive and respiratory syndrome, preparation method thereof, and application thereof

A technology for porcine blue ear disease and high pathogenicity, applied in the field of traditional Chinese veterinary medicine, can solve the problems of large toxic side effects, low cure rate, short immunization time, etc., and achieve the effects of no toxic side effects, significant curative effect, and high cure rate.

Inactive Publication Date: 2012-06-13
QINGDAO AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, "highly pathogenic porcine PRRS" is mostly prevented and treated by vaccination. Common disinfectants such as aldehydes, chlorine-containing disinfectants, phenols, oxidants, compound iodine preparations, and alkalis are used to kill The virus of the disease can be eliminated or the injections such as antiviral interferon, penicillin, spectinomycin, oxytetracycline, etc. can be used to treat the disease. The effect of traditional Chinese medicine preparations is not ideal, the treatment is slow, the course of treatment is long, and the cure rate is low

Method used

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Examples

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Effect test

preparation example Construction

[0079] The present invention also provides the preparation method of the above-mentioned traditional Chinese medicine composition for preventing and treating highly pathogenic porcine blue-ear disease, which comprises:

[0080] The first step is to put Anemarrhena into a multi-functional extraction tank, add ethanol to heat and reflux for extraction, combine the extracts, centrifuge, filter to obtain the filtrate, concentrate under reduced pressure to recover ethanol, obtain extracts, store the extracts in cold storage, and then Dry in a spray dryer, pulverize with a pulverizer and sieve to obtain Anemarrhena powder with a particle size of 50-100 mesh;

[0081] The second step is to pulverize the gypsum, decoct it with water for 2 to 4 times, combine the decoction liquid, filter it, let it rest overnight, extract the upper layer to clear the night, concentrate it under reduced pressure to remove water, dry it into a dry paste, pulverize it with a pulverizer and sieve it to obta...

Embodiment 1

[0113] Embodiment 1 The acute toxicity test of Chinese medicine composition of the present invention to mice

[0114] 1. Test animals

[0115]SPF grade healthy KM mice, 30, half male and half female, weighing 20-25g; purchased from Experimental Animal Center of Sichuan Academy of Traditional Chinese Medicine

[0116] 2. Test drug

[0117] 60g Anemarrhena is packed in the multifunctional extraction tank (Shanghai Shunyi Technology Co., Ltd. production), add 300g 90% ethanol heating reflux extraction 2 times, each 3 hours, combine extraction solution, centrifuge, filter, obtain filtrate, reduce Concentrate under pressure to recover ethanol, stop the recovery when the recovered ethanol quality is 80% of the initially added ethanol quality, obtain the extract, store the extract in refrigerated storage at 0°C, and then enter the spray dryer (Changzhou Kelong Drying Machinery Co., Ltd. (manufactured by the company) in medium drying, the inlet air temperature is 160°C, and the outl...

Embodiment 2

[0142] Embodiment 2 Chinese medicine composition of the present invention is to the long-term toxicity test of sick pig

[0143] Take 10 adult diseased pigs, weighing 150-200 kg, half male and half female, and administer them for a long time for 12 weeks to carry out long-term toxicity test. Abnormal changes were seen, and no pathological changes were found in histopathology and autopsy.

[0144]

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition used for preventing and treating high-pathogenicity porcine reproductive and respiratory syndrome (PPRS). The composition comprises common anemarrhena, gypsum, snakegourd root, common lophatherum herb, reed rhizome, honeysuckle flower, Baikal skullcap root, red peony root, lanceolate dichotomous starwort root, ligusticum, sanna leaf, pilose asiabell root, and Mongolian milkvetch root. According to the invention, when the high-pathogenicity PPRS is treated by using the traditional Chinese medicine composition, the medicine composition is advantaged in substantial treatment effect, high curative rate, no toxic or side-effect, low reoccurrence rate, no drug induced suffering, and low cost. With the traditional Chinese medicinecomposition, both root causes and symptoms can be treated, and the meat quality satisfies a standard of commodity inspections.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese veterinary medicine, in particular to a traditional Chinese medicine composition for preventing and treating highly pathogenic pig blue-ear disease. [0002] Background technique [0003] Ecological pig production is a major industry for the development of animal husbandry in my country, and it is also a main pillar for foreign exchange earnings from the export of animal husbandry products in my country. It is to increase national income and improve people's living standards, accelerate the development of agriculture and animal husbandry, and adjust the structure of agricultural industrialization. important goal. [0004] "Highly pathogenic porcine blue-ear disease", also known as "high fever", is a polar and highly fatal disease caused by a mutant strain of porcine reproductive and respiratory syndrome virus. Since it was introduced into my country in 1995, it has Several large epidem...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P31/14A23K1/16A23K1/14A23K1/18A61K33/06A61K35/36
Inventor 郝智慧曲宝涵
Owner QINGDAO AGRI UNIV
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