Preparation method of compound and its application

A technology for compounds and microbial strains, applied in the preparation of compounds and their application fields, can solve problems such as high cost and difficulty
CN102517221AInactive Publication Date: 2012-06-27BIOTECH CENT OF SHANDONG ACAD OF SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
BIOTECH CENT OF SHANDONG ACAD OF SCI
Publication Date
2012-06-27
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a preparation method of the compound 1, 13-dihydroxy-6-methyl-6, 7, 8, 9, 12, 13, 14, 14a-octyl hydrogen-1H-cyclopentane [f][1] epoxytridecane-4(11aH)-one and its application. The compound is obtained by solid fermentation and extraction separation of a production strain, which is wintersweet Phomopsis chimonanthi that is preserved in China general microbiological culture collection center on December 5, 2011, with a preservation number of CGMCC No 5551. The compound prepared in the invention has inhibiting activity on Aspergillus fumigatus.
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Description

technical field

[0001] The present invention relates to compound 1,13-dihydroxy-6-methyl-6,7,8,9,12,13,14,14a-octane hydrogen-1H-cyclopentane[ f ][1] Preparation method and application of epoxytridecane-4(11aH)-one. Background technique

[0002] Natural products are an important source of lead compounds for the discovery of drugs and pesticides. Natural products are some secondary metabolites produced during the growth and development of microorganisms, plants and animals. Among them, some natural products derived from plants have been used as traditional medicines for thousands of years, and some are still used today, such as the most widely used in the world. The widely used analgesic drug Aspirin (Asprin) is derived from the plants of the genus Salix (Salix) and Populus (Populus); and the first anti-cancer drug (Taxol) with sales exceeding 1 billion US dollars was originally derived from the Pacific plant yew. bark. Scientists such as Fleming and Chain’s research on pe...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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