Unlock instant, AI-driven research and patent intelligence for your innovation.

Traditional Chinese medicine composition for treating glaucoma as well as preparation method and administration mode of same

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine for the treatment of glaucoma, can solve the problems of patients with impaired visual function, optic nerve blindness, vision loss, etc., and achieve the effect of prevention and treatment of optic nerve damage, no drug resistance, and high cure rate

Inactive Publication Date: 2013-09-11
刘娟
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

High intraocular pressure is the basic factor of visual function damage in glaucoma. If the intraocular pressure cannot be effectively controlled, the apoptosis of retinal photoreceptors and ganglion cells, the extensive damage of axons, and the loss of application fibers will cause severe visual dysfunction, resulting in Vision loss and visual field defect can eventually lead to blindness, but long-term clinical and experimental studies have found that after the intraocular pressure of glaucoma is controlled within the normal range, about one-third of patients with glaucoma continue to have impaired visual function, eventually leading to optic atrophy and death. blindness

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine composition for treating glaucoma as well as preparation method and administration mode of same
  • Traditional Chinese medicine composition for treating glaucoma as well as preparation method and administration mode of same

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0054] When the dosage form of the Chinese medicine composition of the present invention is a granule, its preparation method may further comprise the steps:

[0055] The first step is to mix the components according to the stated ratio, add ethanol whose alcohol concentration is 80% to 90% relative to the mixture 3 to 5 times, heat to boiling and reflux for 2 to 4 hours, filter, and use the percolation method Slowly percolate at a rate of 1-2ml per minute, collect the percolation liquid, then concentrate under reduced pressure at a vacuum of 0.06-0.09Mpa to a paste with a relative density of 1.04-1.10 at 50-60°C, spray dry, spray The air inlet temperature of the dryer is 150-170°C, and the outlet air temperature is 75-85°C, and then crushed into powder to make dry paste powder;

[0056] In the second step, 0.3-0.5 times of sucrose powder and 0.1-0.2 times of dextrin are added to the obtained dry paste powder to form granules, and dried at 50-60°C to obtain granules.

[0057]...

Embodiment 1

[0069] The decoction prepared by embodiment 1 Chinese medicine composition of the present invention

[0070] 22g of Tribulus terrestris, 68g of Salvia miltiorrhiza, 48g of medlar, 68g of Chuanxiong, 22g of kudzu root, 33g of ginseng, 12g of white peony root, 9g of Cyperus cyperi, 32g of Ulrich chinensis, 18g of scutellaria baicalensis, 18g of gardenia, 18g of horsetail, 32g of red peony root, 32g, Puhuang 33g, Black Sesame 48g, Apocynum 33g, Cortex Moutan 32g and Borneol 9g are mixed, crushed into powder, the obtained powder is soaked in 2300g of cold water for 36 hours, and decocted with slow fire for 2 hours. The decoction was filtered to obtain the first filtrate, and the filtered residue was added to 600 g of cold water again, decocted with a slow fire for 2 hours, filtered to obtain the second filtrate, and the two filtrates were combined to obtain the decoction.

Embodiment 2

[0071] The granule prepared by embodiment 2 Chinese medicine composition of the present invention

[0072] 22g of Tribulus terrestris, 68g of Salvia miltiorrhiza, 48g of medlar, 68g of Chuanxiong, 22g of kudzu root, 33g of ginseng, 12g of white peony root, 9g of Cyperus cyperi, 32g of Ulrich chinensis, 18g of scutellaria baicalensis, 18g of gardenia, 18g of horsetail, 32g of red peony root, Mix 32g, Puhuang 33g, Black Sesame 48g, Apocynum Apocynum 33g, Moutan Bark 32g and Borneol 9g, add 2300g of ethanol with an alcohol concentration of 90%, heat to boiling and reflux for 3 hours, filter, and use percolation method at a rate of 1ml per minute Percolate at a slow speed, collect the percolation liquid, then concentrate under reduced pressure at 0.09Mpa to a paste with a relative density of 1.10 at 60°C, spray dry, the air inlet temperature of the spray dryer is 170°C, and the outlet air temperature is 85 ℃, and then pulverized into powder to make dry cream powder. Add 230g sucro...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a traditional Chinese medicine composition for treating glaucoma, which comprises caltrop, salvia miltiorrhiza, fructus lycii, ligusticum wallichii, radix puerariae, ginseng, radix paeoniae alba, rhizoma cyperi, fructus leonuri, radix scutellariae, gardenia, horsetail, radix paeoniae rubra, rhizoma sparganii, pollen typhae, semen sesami nigrum, folium apocyni veneti, cortex moutan radicis and borneol. The traditional Chinese medicine composition has the advantages that the traditional Chinese medicine composition is small in side effects, good in curative effect, low in cost, high in cure rate, free from tolerance, and convenient to take; the traditional Chinese medicine composition can well control postoperative intraocular pressure based on an operative treatment, prevents and treats glaucomatous optic neuropathy, and thus better treats the glaucoma.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical engineering, in particular to a traditional Chinese medicine for treating glaucoma. Background technique [0002] Glaucoma is a multifactorial irreversible blinding eye disease characterized by specific optic atrophy and visual field defect. The World Health Organization has listed glaucoma as the second blinding eye disease. The prevalence of primary glaucoma in the population is 14%, and the incidence of blindness and low vision in primary glaucoma are 9.26% and 16.67%, respectively. [0003] The visual function impairment of glaucoma patients is mainly due to ischemia and hypoxia caused by high intraocular pressure or low blood perfusion pressure, which interrupt the axoplasmic flow of optic nerve fibers and cause optic nerve damage. High intraocular pressure is the basic factor of visual function damage in glaucoma. If the intraocular pressure cannot be effectively controlled, the apop...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/902A61K9/08A61K9/16A61P27/06A61K31/045
Inventor 刘娟王子熹姜永华
Owner 刘娟