Medicament for treating II-type diabetes mellitus and preparation method thereof

A type 2 diabetes and drug technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc.

Inactive Publication Date: 2012-08-15
YUNNAN UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there is no report in the prior art on a compound preparation using Astragalus as the monarch drug, supplemented with Atractylodes macrocephala, Coix seed, Pueraria root, Panax notoginseng, Salvia miltiorrhiza, Shengdi, and cinnamon for the treatment of diabetes.

Method used

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  • Medicament for treating II-type diabetes mellitus and preparation method thereof
  • Medicament for treating II-type diabetes mellitus and preparation method thereof
  • Medicament for treating II-type diabetes mellitus and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Prescription: 6 parts of Astragalus, 5 parts of Rehmannia, 4 parts of Yiren, 3 parts of Pueraria Radix, 3 parts of Panax notoginseng, 3 parts of Salvia, 5 parts of Atractylodes macrocephala, and 1 part of cinnamon.

[0030] Preparation method: Grind Panax notoginseng, Salvia miltiorrhiza, Cinnamon, and Atractylodes macrocephala into fine powder, pass through a 100-mesh sieve, 60 C o Regular dosage (10Kgy) is sterilized and ready for use. Add 8 amounts of water to other medicines, soak for 2 hours, boil and extract twice, drain the liquid 1.5 hours after each boiling, combine the two medicine liquids, and filter. Concentrate the filtrate under normal pressure to a relative density of 1.25-1.30, add the above-mentioned fine powder, mix well, dry at low temperature (60°C±5°C), pulverize into fine powder, then add 2% magnesium stearate, mix well, put into capsules, Ready to serve.

Embodiment 2

[0032] Prescription: 3 parts of astragalus, 3 parts of raw land, 2 parts of coix seed, 1 part of kudzu root, 1 part of notoginseng, 2 parts of salvia miltiorrhiza, 1 part of atractylodes rhizome, 1 part of fried atractylodes rhizome, 1 part of cinnamon.

[0033] Preparation method: Grind Panax notoginseng, Salvia miltiorrhiza, and cinnamon into fine powder, pass through a 100-mesh sieve, 60 C o Regular dosage (10Kgy) is sterilized and ready for use. Add 8 times the amount of water to other medicines, soak for 0.5 hours, boil and extract twice, and release the liquid 1.5 hours after each boiling. Combine the two liquid medicines, filter, concentrate the filtrate to a relative density of 1.12 (measured at 25°C), and dry it into a fine powder by spray drying (the drying conditions are that the relative density of the liquid medicine is 1.12, the air inlet temperature is 145°C, and the air outlet temperature is 70-90 ℃, injection speed 2ml / min), add the above-mentioned notoginse...

Embodiment 3

[0035] Prescription: 9 parts of astragalus, 9 parts of raw land, 8 parts of coix seed, 5 parts of kudzu root, 4 parts of notoginseng, 5 parts of salvia miltiorrhiza, 2 parts of Atractylodes macrocephala, 3 parts of cinnamon, 3 parts of safflower, 3 parts of fried atractylodes, and 4 parts of Phellodendron phellodendri.

[0036] Preparation method: Grind Panax notoginseng, Salvia miltiorrhiza, Cinnamon, and Atractylodes macrocephala into fine powder, pass through a 100-mesh sieve, 60 Co routine dose (10Kgy) sterilization, spare. Add 8 amounts of water to other medicines, soak for 2 hours, boil and extract three times, drain the liquid 1.5 hours after each boiling, combine the three medicine liquids, and filter. Concentrate the filtrate under reduced pressure to a relative density of 1.20-1.30, add the above-mentioned fine powder, mix well, dry at low temperature (60°C±5°C), pulverize into fine powder, then add 2% magnesium stearate, mix well, put into capsules, Ready to serve....

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Abstract

The invention provides a medicament for treating diabetes mellitus, which consists of the following raw material drugs in parts by weight: 3 to 40 parts of astragalus mongholicus, 3 to 40 parts of raw rehmannia, 2 to 20 parts of coix seed, 1 to 5 parts of bighead atractylodes rhizome, 1 to 10 parts of kudzuvine root, 1 to 5 parts of red-rooted salvia root, 1 to 4 parts of pseudo-ginseng, and 1 to 3 parts of cinnamon. Furthermore, 1 to 3 parts of fried atratylodes rhizome, and / or 1 to 4 parts of golden cypress and 1 to 3 parts of safflower can be added into the Chinese medicinal compound preparation. The medicament has the functions of strengthening pancreas and consolidating constitution, reducing sugar and regulating fat and the like, and is mainly used for treating II-type diabetes mellitus with symptoms of fatigue and weakness, lack of energy, cumbersome fatigued limbs, even polyuria and polydipsia, numbness of the limbs, pains and the like. The medicament can be manufactured into various oral preparations, and the preparation method of the medicament comprises the following steps: extracting raw materials; and adding proper auxiliary materials.

Description

Technical field: [0001] The invention belongs to the technical field of pharmacy, and in particular relates to a compound traditional Chinese medicine preparation for treating diabetes and a preparation method thereof. Background technique: [0002] Diabetes is a common endocrine and metabolic disease. In recent years, with the development of society and economy in various countries, the incidence of diabetes has been increasing year by year, becoming a major social problem that threatens human health, and has attracted the attention and attention of governments, health departments and medical workers in various countries. [0003] At present, Western medicine mainly contains various insulin preparations and oral hypoglycemic agents or antihyperglycemic agents for the treatment of diabetes. The pathogenesis of type 2 diabetes is mainly based on the existence of two links: insulin resistance and insulin secretion disorders on the basis of genetic defects. Plasma insulin lev...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P3/10
Inventor 李旋珠李文军李竺
Owner YUNNAN UNIV OF TRADITIONAL CHINESE MEDICINE
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