Traditional Chinese medicine composition for treating dairy cow mastitis and preparation method thereof

A composition and mastitis technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve problems such as re-infection, antibiotics reach effective concentration, reduce treatment effect, etc., to overcome milk pollution, impurities Easy to remove and effective treatment

Active Publication Date: 2012-12-19
CHENGDU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, antibiotics are still mainly used in the treatment of mastitis in dairy cows, but people have realized that this cannot fundamentally solve the problem of mastitis in dairy cows, because it is difficult to achieve an effective concentration of antibiotics in milk, especially golden yellow, whether it is systemic or intramammary medication. Staphylococcus and other microorganisms can parasitize in the cells, or form L-type bacteria after antibiotic treatment, and continue to chronically infect the udder. Therefore, long-term and large-scale use of antibiotics not only leads to the emergence of drug-resistant strains and reduces the therapeutic effect, but also reduces the immune function of dairy cows. If it is suppressed, it is easy to cause re-infection. More importantly, drug-resistant bacteria can also be transmitted to people through milk, so that the human body will develop drug resistance after drinking this milk for a long time.
[0004] Most of the existing traditional Chinese medicines for the treatment of dairy cow mastitis are made of more than four kinds of raw materials. Although they have a certain therapeutic effect, due to the large number of raw materials, there are also many impurities, and there may be some impurities that are difficult to remove
In addition, the large amount of raw materials also leads to a large final dosage, which not only makes administration difficult, but also easily leads to adverse reactions in cows after administration.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1 (injection)

[0030] Recipe: Green bark 250g, licorice 250g, dandelion 500g

[0031] Preparation:

[0032] (1) Take green bark, licorice and dandelion according to the above weight ratio, add 15 times the total weight of water to extract 3 times, each time for 1 hour, combine the extracts, concentrate the extracts to a relative specific gravity of 1.20, and then add ethanol to make the containing The alcohol content is 80%, let it stand for 24 hours, filter, take the filtrate, concentrate it under reduced pressure to a relative specific gravity of 1.25, and dry to obtain the intermediate;

[0033] (2) Take 1000ml of water for injection, heat it to boiling, then add the above-mentioned intermediate, and stir evenly, adjust its pH value to 6-8, heat it to boiling for about 15 minutes after stirring evenly, then cool to room temperature and then place at 0 Refrigerate at -4°C for 24 hours, filter, take the filtrate and heat it to boiling, then add activated ...

Embodiment 2

[0035] Embodiment 2 (granule)

[0036] Recipe: green bark 200g, licorice 300g, dandelion 600g

[0037] Preparation:

[0038] (1) Take green bark, licorice and dandelion according to the above weight ratio, add 8 times the total weight of water to extract twice, each time for 1 hour, combine the extracts, concentrate the extracts to a relative specific gravity of 1.10, and then add ethanol to make the containing The alcohol content is 65%, let it stand for 24 hours, filter, take the filtrate, concentrate it under reduced pressure to a relative specific gravity of 1.25, and dry to obtain the intermediate, add an appropriate amount of dextrin to the intermediate, granulate, dry, and prepare After granulation, the granules of the present invention are obtained.

[0039] Usage and dosage: mix it into the feed, 3 times a day, 10-50g each time.

Embodiment 3

[0040] Embodiment 3 (injection)

[0041] Recipe: green bark 350g, licorice 250g, dandelion 400g

[0042] Preparation:

[0043] (1) Take green bark, licorice and dandelion according to the above weight ratio, add 20 times the total weight of water to extract 3 times, each time for 1.5 hours, combine the extracts, concentrate the extracts to a relative specific gravity of 1.20, and then add ethanol to make the containing The alcohol content is 85%, let it stand for 24 hours, filter, take the filtrate, concentrate it to dryness under reduced pressure until the relative specific gravity is 1.25, and dry to obtain the intermediate;

[0044] (2) Take 1000ml of water for injection, heat it to boiling, then add the above-mentioned intermediate, and stir evenly, adjust its pH value to 6-8, heat it to boiling for about 15 minutes after stirring evenly, then cool to room temperature and then place at 0 Refrigerate at -4°C for 24 hours, filter, take the filtrate and heat it to boiling, ...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating dairy cow mastitis. The traditional Chinese medicine composition is a medicament prepared from the following raw materials expressed in weight parts: 5 to 8 parts of green tangerine peel, 5 to 8 parts of liquorice root and 8 to 15 parts of dandelion. The traditional Chinese medicine composition provided by the invention has the effects of clearing heat, removing toxins, activating blood circulation to expel blood stasis and resolve static blood, removing edema and promoting lactation and can overcome defects like milk pollution and poor quality of dairy products caused by antibiotic treatment. According to results of clinical diagnosis and treatment, the traditional Chinese medicine composition has a remarkable treatment effect, and milk yield of a dairy cow quickly returns to normal after the dairy cow is healed.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating cow mastitis and a preparation method thereof. Background technique [0002] Bovine mastitis refers to a kind of dairy cow mammary gland inflammation caused by microbial infection or physical and chemical stimulation, which can be caused by a variety of bacteria together or alone, and is one of the diseases that cause the most serious losses in the dairy industry. According to literature reports, there are about 220 million dairy cows in the world, and about 1 / 3 of them suffer from various types of mastitis. Dairy cow mastitis, as a common and frequently-occurring disease in the dairy farming industry, causes huge economic losses every year. The occurrence of mastitis in dairy cows also has a great impact on the quality of milk, and the flow of pathogenic milk into the market is likely to cause public health incidents. Therefore, the scientific prevention and treatment o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61P15/14
Inventor 刘涛徐玉玲郭晓恒
Owner CHENGDU UNIV
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