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A Chinese medicine composition for the treatment of breast hyperplasia and its preparation method

A breast hyperplasia and composition technology, which is applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems of poor patient compliance, large daily doses, and complicated preparation processes, and achieves short course of treatment and curative effect. Stable, simple preparation method

Active Publication Date: 2013-01-02
XIAN CHIHO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the many components in the above-mentioned Chinese patent medicine, the preparation process is complicated, the cost is high, and the daily dose is large (capsule 0, 5 capsules / time, 3 times / day), the patient not only has poor compliance, but also has to bear a serious economic burden.

Method used

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  • A Chinese medicine composition for the treatment of breast hyperplasia and its preparation method
  • A Chinese medicine composition for the treatment of breast hyperplasia and its preparation method
  • A Chinese medicine composition for the treatment of breast hyperplasia and its preparation method

Examples

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Effect test

Embodiment 1

[0024] Prescription of traditional Chinese medicine composition:

[0025] 40 parts of dandelion; 20 parts of red peony; 30 parts of Bupleurum; 30 parts of Corydalis.

[0026] The preparation method is as follows:

[0027] (1) Take the prescribed amount of dandelion, red peony root, Bupleurum and Corydalis, add water and decoct three times, add 12 times the amount of water for the first time, and decoct for 2 hours; add 10 times the amount of water for the second time, decoct for 1.5 hours; Add 8 times the amount of water three times, decoct for 1 hour, combine the three times of filtrate, and set aside;

[0028] (2) Get above-mentioned filtrate centrifugation 20 minutes (1500 revs / min), carry out ultrafiltration with the cellulose acetate membrane that molecular weight is 50,000 Daltons then, pressure 0.1MPa, ultrafiltrate is standby;

[0029] (3) spray drying the above-mentioned ultrafiltrate to obtain dry powder;

[0030] (4) Add an appropriate amount of magnesium stearat...

Embodiment 2

[0032] Prescription of traditional Chinese medicine composition:

[0033] 50 parts of dandelion; 25 parts of red peony; 25 parts of Bupleurum; 20 parts of Corydalis.

[0034] The preparation method is as follows:

[0035](1) Take the prescribed amount of dandelion, red peony root, Bupleurum and Corydalis, add water and decoct three times, add 12 times the amount of water for the first time, decoct for 3 hours; add 8 times the amount of water for the second time, decoct for 1 hour; Add 6 times the amount of water three times, decoct for 0.5 hours, combine the three filtrates, and set aside;

[0036] (2) Get above-mentioned filtrate and carry out centrifugation (10 minutes, 3000 revs / min), then carry out ultrafiltration with the polyethersulfone membrane that molecular weight is 100,000 Daltons, pressure 0.05MPa, ultrafiltrate is standby;

[0037] (3) Get the above-mentioned ultrafiltrate and carry out spray drying to obtain dry powder;

[0038] (4) Add an appropriate amount ...

Embodiment 3

[0040] Prescription of traditional Chinese medicine composition:

[0041] 60 parts of dandelion; 25 parts of red peony; 20 parts of Bupleurum; 25 parts of Corydalis.

[0042] The preparation method is as follows:

[0043] (1) Take the prescribed amount of dandelion, red peony root, Bupleurum and Corydalis and decoct twice, add 12 times the amount of water for the first time, decoct for 2 hours; add 10 times the amount of water for the second time, decoct for 1.5 hours, Merge the two filtrates for subsequent use;

[0044] (2) Get above-mentioned filtrate and carry out centrifugation pretreatment (10 minutes, 5000 revs / min), then carry out ultrafiltration with the polyamide membrane that molecular weight is 10,000 Daltons, pressure 0.2MPa, ultrafiltrate is standby;

[0045] (3) spray drying the ultrafiltrate to obtain dry powder;

[0046] (4) Add an appropriate amount of starch to the fine powder obtained in step (3), mix evenly, add an appropriate amount of 80% ethanol to gr...

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Abstract

The invention provides a Chinese medicine composition for the treatment of breast hyperplasia and its preparation method. The Chinese medicine composition is prepared from the following crude drugs according to part by weight: dandelion 40-60, paeony 20-30, Chinese thorowax root 20-30, and corydalis tuber 20-30. The dandelion, paeony, Chinese thorowax root and corydalis tuber are subjected to decoction and extraction with water and then purification with ultrafiltration technology. The Chinese medicinal composition is specifically for the treatment of breast hyperplasia, achieves the effects of dispersing stagnated liver qi, resolving stagnation, softening and resolving hard mass, and promoting circulation of qi and to relieve pain with only four kinds of crude drugs, can be used for treating breast hyperplasia or mastitis induced by liver qi stagnation, and stagnation of toxin and stasis, and has advantages of no adverse side effect, simple preparation, convenient use, short course of treatment, and stable treatment effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating mammary gland hyperplasia and a preparation method thereof. Background technique [0002] In recent years, mammary gland hyperplasia has become the main killer of urban women. According to the survey, about 70% to 80% of women have hyperplasia of mammary glands in various degrees, and it is more common in women aged 25 to 45. Modern medicine believes that mammary gland hyperplasia refers to the hyperplasia of mammary gland epithelium and fibrous tissue, the structural degeneration of breast tissue ducts and lobules, and the growth of progressive connective tissue. The cause of the disease is mainly due to endocrine hormone imbalance. Once suffering from hyperplasia of mammary glands, in addition to pain and lumps, the patient must have emotional irritability, irritability, fear, etc., and physiologically functional decline, such as apathy, menstrual disorders, physical de...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61P15/14
Inventor 胡小虎李文强
Owner XIAN CHIHO PHARMA
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