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Wheat bran extract healthcare food with blood sugar reduction function and preparation method thereof

The technology of health food and extract is applied in the field of health food of wheat bran extract, which can solve the problems of unclear efficacy and components of hypoglycemic effect, and achieve the effects of reducing toxic and side effects, treatment cost, low price and abundant raw material sources.

Inactive Publication Date: 2013-04-03
JIANGSU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006]However, the functional components in wheat bran that have hypoglycemic effect are still unclear. After a lot of research, the inventor found for the first time that the alkyl group in wheat Resorcinol, Apigenin, Glyceryl Phosphate, Sterols have α-glucosidase inhibitory activity, Thus, the material basis of the hypoglycemic effect of wheat bran was expounded, and an effective extraction method was obtained through research

Method used

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  • Wheat bran extract healthcare food with blood sugar reduction function and preparation method thereof
  • Wheat bran extract healthcare food with blood sugar reduction function and preparation method thereof
  • Wheat bran extract healthcare food with blood sugar reduction function and preparation method thereof

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Effect test

Embodiment 1

[0026] Step 1: Preparation of Wheat Bran Extract

[0027] 100 g of wheat bran was extracted with 10 times of 95% ethanol for 48 h, filtered and concentrated under reduced pressure to obtain the alcohol extract extract. The alcohol extraction extract was dissolved with a small amount of double distilled water, extracted with petroleum ether, the petroleum ether phase was concentrated under reduced pressure, and dried by nitrogen blowing to obtain dry powder of wheat bran extract.

[0028] Step 2: Method for separating and extracting various hypoglycemic active ingredients from wheat bran

[0029] Take 10 g of the wheat bran extract obtained in step 1, separate and purify it through a silica gel column (200-300 mesh, 2.5×60 cm), and elute with petroleum ether-ethyl acetate (100:0-80:20) at a flow rate of 2 drops / second, collect the eluent of different components of petroleum ether-ethyl acetate (90:10-80:20), concentrate and dry to obtain dry powder.

[0030] Step 3: Purificat...

Embodiment 2

[0040] Step 1: Preparation of Wheat Bran Extract

[0041] 100 g of wheat bran was extracted with 10 times of 95% ethanol for 48 h, filtered and concentrated under reduced pressure to obtain the alcohol extract extract. The alcohol extraction extract is dissolved in a small amount of double-distilled water, extracted with petroleum ether, the petroleum ether phase components are concentrated under reduced pressure, and dried by nitrogen blowing to obtain dry powder of wheat bran extract.

[0042] Step 2: Method for separating and extracting various hypoglycemic active ingredients from wheat bran

[0043] Take 10 g of the wheat bran extract obtained in step 1, separate and purify it through a silica gel column (200-300 mesh, 2.5×60 cm), and elute with petroleum ether-ethyl acetate (100:0-80:20) at a flow rate of 2 drops / second, collect the eluent of different components of petroleum ether-ethyl acetate (90:10-80:20), concentrate and dry to obtain dry powder.

[0044] Step 3: P...

Embodiment 3

[0053] Step 1: Preparation of Wheat Bran Extract

[0054] 100 g of wheat bran was extracted with 10 times of 95% ethanol for 48 h, filtered and concentrated under reduced pressure to obtain the alcohol extract extract. The alcohol extraction extract is dissolved in a small amount of double-distilled water, extracted with petroleum ether, the petroleum ether phase components are concentrated under reduced pressure, and dried by nitrogen blowing to obtain dry powder of wheat bran extract.

[0055] Step 2: Method for separating and extracting various hypoglycemic active ingredients from wheat bran

[0056] Take 10 g of the wheat bran extract obtained in step 1, separate and purify it through a silica gel column (200-300 mesh, 2.5×60 cm), and elute with petroleum ether-ethyl acetate (100:0-80:20) at a flow rate of 2 drops / second, collect the eluent of different components of petroleum ether-ethyl acetate (90:10-80:20), concentrate and dry to obtain dry powder.

[0057] Step 3: P...

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Abstract

The invention provides a wheat bran extract healthcare food with a blood sugar reduction function and a preparation method thereof, and belongs to the technical field of healthcare foods. The healthcare food comprises 10-90% of an active wheat bran extract and 90-10% of edible auxiliary materials according to weight percentage. The invention also provides the preparation method of the wheat bran extract healthcare food with the blood sugar reduction function. The wheat bran extract healthcare food provided by the invention has a good function of reducing the blood sugar and has the following advantages: the raw materials are derived from foods and are safe and nontoxic; the raw material resources are wide and the raw materials are cheap in price; toxics and side effects and the treatment cost in the drug therapy process of a diabetic patient are effectively reduced; and the wheat bran extract healthcare food is widely applied in both the medical clinic and the daily life of people.

Description

technical field [0001] The invention belongs to the technical field of health food. It specifically relates to a health food of wheat bran extract, which can inhibit the activity of α-glucosidase, has good preventive and therapeutic effects on type 2 diabetes, and can be used in the preparation of health food and medicine related to the prevention and treatment of type 2 diabetes. develop. Background technique [0002] Diabetes Mellitus (DM) is a chronic, hereditary disease accompanied by the inability of body tissues to metabolize carbohydrates, lipids and proteins normally due to absolute or relative insufficient secretion of insulin, resulting in metabolic disorders of the body. Its main characteristics are Hyperglycemia and diabetes, its complications include hypertension, cardiovascular and cerebrovascular diseases, retinopathy, diabetic nephropathy, etc. At present, due to its high incidence in the world, diabetes is considered to be one of the most serious diseases ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/10A23L1/308A23L7/10
Inventor 屠洁陈钧
Owner JIANGSU UNIV
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