Composite enteral nutrition applicable to AIDS patients

Abstract

The invention discloses a composite enteral nutrition applicable to AIDS patients. The composite enteral nutrition comprises nutrients such as proteins, fat, carbohydrates, vitamins, minerals and dietary fibers required by human bodies. The nutrition has a good clinical nutritional supporting effect on the AIDS patients, is beneficial to absorption of the AIDS patients and improvement of poor nutrient conditions of the patients compared with a common whole protein type nutrition, and can obviously improve the living quality of the patients; compared with a common nutrient group, the nutrition has the advantages of remarkably improving the nutrient conditions of the patients and lightening the decline of various physical measurement indexes such as weight caused by AIDS; various biochemical indexes of blood of the patients can be remarkably improved, the blood sugar and the blood fat of the patients are adjusted, and the insulin resistance and the lipid metabolism disorder of the patients are lightened; and the intestinal floras of the patients are adjusted, the intestinal barrier function of the patients is protected, diarrhea caused by the flora disorder of the patients is reduced, the immunity of the patients is enhanced, and the opportunistic infections caused by intestinal flora translocation are reduced.

Description

technical field [0001] The invention relates to a compound enteral nutrition preparation suitable for AIDS patients. Background technique [0002] AIDS (Acquired Immunodeficiency Syndrome, AIDS) is a chronic wasting infectious disease caused by human immunodeficiency virus (Human Immunodeficiency Virus, HIV). Since it was first discovered in the United States in 1981, the epidemic has developed rapidly. Its clinical symptoms are complex, complications are numerous, and the fatality rate is extremely high. At present, it has become one of the most destructive epidemic diseases in history. China first reported the discovery of AIDS patients in 1985. By the end of 2011, a total of 434,000 HIV-infected and AIDS patients had been reported, including 88,000 deaths. It is estimated that there are about 780,000 living HIV-infected and AIDS patients (about 15.4 million people). In recent years, the prevalence of AIDS in my country has continued to rise; in the process of AIDS preve...

AI Technical Summary

Problems solved by technology

[0006] 1. Increased basal consumption: The average resting energy expenditure (REE) of lean body tissue (fat-free mass, FFM) in HIV-infected patients was significantly higher in HIV-positive patients than in healthy controls. The amplitude is about 9%, and the REE increase degree of symptomatic infection is more obvious than that of asymptomatic infection, combined with opportunistic infection or tumor, resulting in increased energy and protein requirements, as well as nutrient loss and utilization barriers;

[0007] 2. Intestinal barrier function damage and bacterial flora imbalance lead to digestive and absorption dysfunction and long-term hypoalbuminemia: HIV-infected patients and AIDS patients have mucosal inflammation in the gastrointestinal tract, which is related to the patient's cell cycle, lipid metabolism, intestinal Down-regulation of genes related to mucosal barrier and digestive function, decreased ability of mucosal repair and regeneration, bacterial flora imbalance and other pathological changes lead to loss of appetite, abdominal distension, diarrhea, weight loss, intestinal inflammatory edema, and increased intestinal permeability in AIDS patients , bile acid and vitamin B12 malabsorption, etc. AIDS patients have significant intestinal microecological imbalance, digestive dysfunction, and lack of nutrients related to intestinal microecology, such as vitamin B and K vitamins; patients with long-term chronic diarrhea, increased intestinal Translocation of intestinal flora leads to systemic immune activation and accelerates the occurrence of AIDS and opportunistic infections;

[0010] Malnutrition has become the main challenge faced by HIV-infected and AIDS patients. Nutritional support therapy is of great significance to AIDS wasting syndrome and is one of the effective adjuvant treatments. Because HIV infection affects all organ systems , Metabolic changes of infected persons and toxic side effects caused by HAART treatment. AIDS patients need a special nutritional preparation that is configured according to the characteristics of AIDS patients and suitable for their pathophysiological changes for nutritional support. In addition, Yunnan Province is a high-incidence area of ​​AIDS. No enteral nutrition preparations for AIDS patients

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