18 results about "K vitamins" patented technology

Various benefits to intestinal health are made by delivery of an active agent to the colon of an animal, including a human. Active ingredients include of riboflavin, vitamin A, vitamin C, vitamin D, vitamin E, vitamin K, folic acid, β-carotene, vitamin B1, niacin, vitamin B5, vitamin B6, biotin, vitamin B12, omega-3 fatty acids and combinations thereof. Benefits include increased concentration of at least one short-chain fatty acid its salt thereof in the intestine, increased microbiome diversity in the intestine, increased beneficial bacteria in the intestine, increased the butyrate synthesis pathway in the intestine, improved barrier function of the intestine, reduced redox potential of the gut, reduced amount of gas produced in the intestine; and stimulation of intestinal immune responses.

The invention relates to the technical field of biological medicine preparations, and discloses a calcium, vitamin D and vitamin K. A content composition of the soft capsule comprises a microgel skeleton composed of amphiphilic polypeptide calcium ions and vitamin oil drops, the hydrophobic end of amphiphilic polypeptide adsorbs the oil drops, and the hydrophobic end of the amphiphilic polypeptide adsorbs the vitamin oil drops. A hydrophilic end of the composition is bridged by calcium ions to form a network, the composition also comprises a histidine-enriched polypeptide which can form a protective shielding layer on the surface of a skeleton under acidic pH, the calcium ions are converted from a chemical destroyer to a structural stabilizer, and a static synergistic system is constructed, so that the contact degradation of calcium and vitamins is eliminated, and the stability of the composition is improved. The performance contradiction between the high calcium content and the vitamin stability is avoided, and the endophytic environmental adaptability of the composition is improved.

The invention belongs to the technical field of medicinal preparation processing, and particularly relates to oral liquid for supplementing calcium, vitamin D and vitamin K and a preparation method of the oral liquid. The fruit and vegetable powder is prepared from the following raw materials in parts by weight: 100 to 500 parts of calcium citrate, 0.2 to 2.5 parts of vitamin D3 emulsion, 0.4 to 5.5 parts of vitamin K2, 0 to 100 parts of casein phosphopeptides, 0.1 to 200 parts of fruit and vegetable powder, 0 to 5 parts of citric acid, 0 to 5 parts of malic acid, 0.1 to 400 parts of a sweetening agent, 0.01 to 10 parts of a thickening agent, 0.1 to 5 parts of an emulsifying agent, 0 to 2 parts of stevioside and 665 to 1395 parts of water. According to the invention, the vitamin D3 emulsion process is improved, the proper antioxidant is added, and the proper consistency is adjusted, so that the stability of the vitamin D3 in the oral liquid product is ensured, and the dosage form application range of the calcium supplement is enlarged.

The utility model relates to the field of feeding devices, in particular to a feeding device of a vitamin K drop colloid mill, which comprises an ingress pipe, a connecting pipe is arranged above the guide-in pipe, and a hopper is arranged above the connecting pipe. After the device is used for a period of time, the ingress pipe, the connecting pipe and the hopper are sequentially disassembled, the inner walls of the ingress pipe, the connecting pipe and the hopper are cleaned, then the ingress pipe, the connecting pipe and the hopper are sequentially assembled, and then the lower end of the ingress pipe is mounted on equipment, so that the device can be continuously used; through the method, material residues on the inner surfaces of all parts of the feeding device can be thoroughly removed, the residual materials are prevented from being mixed into new products in the next production process, so that the purity and the ingredient accuracy of the vitamin K drops are guaranteed, the products are prevented from being polluted or the quality is prevented from fluctuating, the breeding environment of bacteria and microorganisms can be reduced through the clean feeding device, and the production efficiency is improved. And the safety and the stability of the product can be ensured.

The invention relates to the technical field of fermentation, in particular to a protein composition for promoting calcium absorption and muscle synthesis and preparation and application thereof. The protein composition comprises the following components in parts by weight: 0.5-99 parts of yeast protein and 0.5-20 parts of a calcium source, the protein content in the yeast protein is more than or equal to 70%, and the zinc content in the yeast protein is more than or equal to 200mg / kg; in terms of the weight of the yeast protein, the content of serine in the yeast protein is larger than or equal to 50 mg / g, and / or the content of glutamic acid is larger than or equal to 110 mg / g, and / or the content of leucine is larger than or equal to 90 mg / g, and / or the content of isoleucine is larger than or equal to 55 mg / g, and / or the content of valine is larger than or equal to 50 mg / g, and / or the content of lysine is larger than or equal to 94 mg / g. The protein composition prepared by combining the yeast protein as a main raw material with the calcium source and nutritional ingredients such as the vitamin D, the vitamin K, the collagen or the casein phosphopeptides not only can promote absorption and utilization of calcium, but also can promote muscle synthesis and improve muscle quality, so that the requirement of collaborative health of muscles and bones is met.

A method comprising the steps of: (a) assessing an expression level of at least one protein, selected from Table 1, 2 or 3 in a sample from a subject, where in the at least one protein may be selected from the list comprising: Beta-Ala-His dipeptidase, Apolipoprotein L1, Methanethiol oxidase, Vitamin K-dependent protein S, von Willebrand factor, Plasminogen, Selenoprotein P, Protein disulfide-isomerase A6 and Inter-alpha-trypsin inhibitor heavy chain H3, and (b) using the expression level to determine whether the subject has endometriosis.

The invention discloses a pharmaceutical composition for delaying senescence and resisting oxidation, and belongs to the technical field of biological medicine and health food. The composition comprises vitamin A, beta-carotene, vitamin complex B, vitamin C, vitamin D, vitamin E, vitamin k, macroelements including calcium, phosphorus, potassium and magnesium, microelements including zinc, selenium, iron, chromium, copper, molybdenum, iodine, fluorine and manganese, traditional Chinese medicines including ginseng, astragalus membranaceus, fructus lycii and radix polygoni multiflori preparata, and condition essential nutrient nucleic acid. The bioactive components comprise lycopene, tea polyphenol, taurine, lutein, lutein fat, zeaxanthin, chlorophyll and the like; is mainly suitable for middle-aged and elderly people; the composition eliminates multiple factors causing aging from multiple systems, multiple links and multiple targets, can significantly delay aging, has health-care and tonifying effects such as oxidation resistance, and can improve the life quality of middle-aged and elderly people while delaying aging; the composition has no incompatibility, and does not generate any toxic or side effect after being taken for a long time.

The invention provides a micro-fat calcium supplement carrier, which is prepared from the following raw materials in parts by weight: 30 to 35 parts of standard index calcium, 1 to 5 parts of chondroitin, 1 to 5 parts of glucosamine, 8 to 12 parts of pure camel milk, 0.7 part of vitamin D, 2 to 70.3 parts of vitamin K, 1 to 3 parts of phospholipid complex and 8 to 10 parts of excipient. According to the invention, standard calcium, chondroitin, glucosamine, pure camel milk, vitamin D, vitamin K2-7, a phospholipid complex and an excipient are organically mixed by adopting a liposome carrier technology, so that the digestion and absorption of calcium in a body and the distribution of calcium in a specific region are effectively improved, and further the effects of rapid bone growth, increase of bone length (promotion of height increase) and increase of bone density are achieved; the health-care food has the health-care functions of reducing the fracture probability, preventing tooth decay, reducing the death rate of cardiovascular diseases and the like, so that the calcium absorption rate is remarkably improved and reaches up to 95%.

The invention discloses a pharmaceutical composition for preventing birth defects and improving memory, and belongs to the technical field of biological medicine and health food. The composition comprises vitamin A, beta-carotene, vitamin complex B, vitamin C, vitamin D, vitamin E, vitamin k, macroelements including calcium, phosphorus, potassium and magnesium and microelements including zinc, selenium, iron, chromium, copper, molybdenum, iodine, fluorine and manganese, traditional Chinese medicines including glossy privet fruit, astragalus membranaceus, fructus lycii, semen cuscutae and nucleic acid, and bioactive components including lutein, lutein fat, zeaxanthin, grape seed extract, chlorophyll and taurine. The device is mainly used for pre-pregnancy preparation of pregnant women, dosages thereof, pregnant women and wet nurses. The composition eliminates various factors causing birth defects from multiple systems, multiple links and multiple targets, can significantly reduce the total occurrence rate of birth defects, has the effect of improving memory, is beneficial to the health of parents and children, has no incompatibility, and does not generate any toxic or side effect after being taken for a long time.

The invention discloses application of dihydromyricetin as a regulator for reducing the content of vitamin K, and belongs to the field of biological medicine. The invention discloses dihydromyricetin which can be used for preparing a product for reducing the content of vitamin K in blood. The dihydromyricetin disclosed by the invention can up-regulate expression of an NQO1 gene and protein and promote conversion of vitamin K into a vitamin K precursor substance, so that the content of vitamin K in blood is reduced.

The application provides a child formula milk for promoting bone development and a preparation method thereof, and relates to the technical field of dairy products.The child formula milk for promoting bone development comprises the following raw materials in mass parts: raw cow milk 970-999 parts, a composite vitamin 0.05-1 part, a mineral 0.1-1.5 parts, colostrum basic protein 0.1-1 part and 2'-fucosyllactose 0.1-2 parts; the composite vitamin contains vitamin K, and the mass ratio of 2'-fucosyllactose to the composite vitamin is 0.5:1-20:1; the mass ratio of colostrum basic protein:2'-fucosyllactose: vitamin K: mineral is 1:(1-10):(0.1-0.5):(0.5-10). The child formula milk for promoting bone development can effectively promote bone development and improve product stability through specific content matching of each raw material component.

This invention provides a probiotic, a probiotic composition, and their applications, all possessing the functions of calcium ion enrichment and vitamin K synthesis. This invention belongs to the field of microbial technology. The probiotic provided by this invention is *Lactobacillus bulgaricus* subsp. Lactobacillus delbrueckii subsp. bulgaricus NWP-101 or Pyrococcus lactis ( Pediococcus acidilactici NWP-299 has the advantages of efficient calcium enrichment, high vitamin K production and excellent probiotic properties. It can be used to prepare probiotic preparations, functional foods, health foods or dietary supplements to prevent or improve osteoporosis and increase bone density.

The invention discloses a pharmaceutical composition for delaying senescence and resisting oxidation, and belongs to the technical field of biological medicine and health food. The composition comprises vitamin A, beta-carotene, vitamin complex B, vitamin C, vitamin D, vitamin E, vitamin k, macroelements including calcium, phosphorus, potassium and magnesium, microelements including zinc, selenium, iron, chromium, copper, molybdenum, iodine, fluorine and manganese, traditional Chinese medicines including ginseng, astragalus membranaceus, schisandra chinensis and radix polygoni multiflori preparata, and condition essential nutrient nucleic acid. The bioactive components comprise lycopene, tea polyphenol, taurine, lutein, lutein fat, zeaxanthin, chlorophyll and the like; is mainly suitable for middle-aged and elderly people; the composition eliminates multiple factors causing aging from multiple systems, multiple links and multiple targets, can significantly delay aging, has health-care and tonifying effects such as oxidation resistance, and can improve the life quality of middle-aged and elderly people while delaying aging; the composition has no incompatibility, and does not generate any toxic or side effect after being taken for a long time.

This invention relates to a selenium-containing compound vitamin chewable tablet and its preparation method, comprising the following raw materials in parts by weight: 10-16 parts selenium-enriched yeast, 25-35 parts L-ascorbic acid, 0.5-1 part vitamin K, 10-20 parts sorbitol, 1-3 parts DL-α-tocopherol acetate, 3-8 parts sodium octenyl succinate starch, 1-5 parts acetylated distarch adipate, 0.7-1.2 parts magnesium stearate, 0.3-0.5 parts potassium citrate, 0.04-0.07 parts steviol glycosides, and 5-10 parts modified silica. This invention improves the crispness and palatability of the chewable tablet by adding acetylated distarch adipate and sodium octenyl succinate starch; the addition of modified silica effectively reduces vitamin attenuation and improves the stability of the components.

The invention provides a lactobacillus reuteri high-density fermentation method and application thereof, and belongs to the technical field of microbial fermentation. According to the fermentation method provided by the invention, the heme, the vitamin K compound and the inducer are exogenously added, so that the problem of active oxygen toxicity associated with aerobic respiration is effectively reduced, carbon metabolic repression generated by glucose is avoided, and the utilization efficiency of sucrose in the fermentation process is remarkably improved; and the high-speed proliferation of the thalli is ensured, and meanwhile, the extremely high cell activity is kept. Experimental data show that the viable count of the fermentation liquor can break through 1 * 10 < 11 > CFU / mL only in 8-9 hours, and the viable count of a final product can be larger than or equal to 1 * 10 < 13 > CFU / mL within 10 hours. According to the technology, the seed propagation cost and the time cost are greatly reduced, the obtained thalli are high in mechanical strength and stress resistance, and a creative solution is provided for efficient industrial production of lactobacillus reuteri.

The invention discloses a pharmaceutical composition for preventing birth defects and improving memory, and belongs to the technical field of biological medicine and health food. The composition comprises vitamin A, beta-carotene, vitamin complex B, vitamin C, vitamin D, vitamin E, vitamin k, macroelements (calcium, phosphorus, potassium and magnesium), microelements (zinc, selenium, iron, chromium, copper, molybdenum, iodine, fluorine and manganese), traditional Chinese medicines (astragalus membranaceus, fructus lycii and semen cuscutae), and bioactive components (grape seed extract, chlorophyll and taurine). The device is mainly used for pre-pregnancy preparation of pregnant women, dosages thereof, pregnant women and wet nurses. The composition eliminates various factors causing birth defects from multiple systems, multiple links and multiple targets, can remarkably reduce the total incidence rate of birth defects, has the effects of improving memory, protecting health and tonifying, is beneficial to the health of parents and children, has no incompatibility, and does not generate any toxic or side effect after being taken for a long time.

The application provides a chicken feed additive and application thereof, and belongs to the technical field of feed additives.The chicken feed additive comprises the following raw materials: organic manganese, hydroxyl vitamin D, calcium hydrogen phosphate, stone powder, sodium chloride, methionine, lysine, vitamin A, vitamin D, vitamin K, vitamin E, phytase, choline, baking soda, copper sulfate, ferrous sulfate, zinc sulfate, potassium iodide and sodium selenite.The raw materials of the chicken feed additive are easy to obtain, can be directly added to conventional laying hen feed for use, are convenient to apply and controllable in cost.The additive can effectively relieve oxidative stress in the liver, reduce the level of pro-inflammatory cytokines in the liver, thereby reducing liver inflammation, and can well inhibit fat deposition.

The method for confirming nutrient attenuation in frozen food according to the present invention is characterized by comprising: a step for performing an accelerated test on frozen food at a temperature of 0 DEG C or more and a high pressure of 90 MPa or more; and a step for analyzing the nutrients contained in the frozen food after the accelerated test. The method is also characterized in that the nutrient to be confirmed is at least one of the following: retinol, alpha-carotene, beta-carotene, beta-cryptoxanthin, vitamin D, alpha-tocopherol, vitamin K, vitamin B1, vitamin B2, nicotinic acid, vitamin B6, vitamin B12, folic acid, pantothenic acid, biotin, vitamin C, n-3 polyunsaturated fatty acids and n-6 polyunsaturated fatty acids.