40 results about "K vitamins" patented technology

Various benefits to intestinal health are made by delivery of an active agent to the colon of an animal, including a human. Active ingredients include of riboflavin, vitamin A, vitamin C, vitamin D, vitamin E, vitamin K, folic acid, β-carotene, vitamin B1, niacin, vitamin B5, vitamin B6, biotin, vitamin B12, omega-3 fatty acids and combinations thereof. Benefits include increased concentration of at least one short-chain fatty acid its salt thereof in the intestine, increased microbiome diversity in the intestine, increased beneficial bacteria in the intestine, increased the butyrate synthesis pathway in the intestine, improved barrier function of the intestine, reduced redox potential of the gut, reduced amount of gas produced in the intestine; and stimulation of intestinal immune responses.

Various benefits to intestinal health are made by delivery of an active agent to the colon of an animal, including a human. Active ingredients include of riboflavin, vitamin A, vitamin C, vitamin D, vitamin E, vitamin K, folic acid, β-carotene, vitamin B1, niacin, vitamin B5, vitamin B6, biotin, vitamin B12, omega-3 fatty acids and combinations thereof. Benefits include increased concentration of at least one short-chain fatty acid its salt thereof in the intestine, increased microbiome diversity in the intestine, increased beneficial bacteria in the intestine, increased the butyrate synthesis pathway in the intestine, improved barrier function of the intestine, reduced redox potential of the gut, reduced amount of gas produced in the intestine; and stimulation of intestinal immune responses.

The invention relates to the technical field of biological medicine preparations, and discloses a calcium, vitamin D and vitamin K. A content composition of the soft capsule comprises a microgel skeleton composed of amphiphilic polypeptide calcium ions and vitamin oil drops, the hydrophobic end of amphiphilic polypeptide adsorbs the oil drops, and the hydrophobic end of the amphiphilic polypeptide adsorbs the vitamin oil drops. A hydrophilic end of the composition is bridged by calcium ions to form a network, the composition also comprises a histidine-enriched polypeptide which can form a protective shielding layer on the surface of a skeleton under acidic pH, the calcium ions are converted from a chemical destroyer to a structural stabilizer, and a static synergistic system is constructed, so that the contact degradation of calcium and vitamins is eliminated, and the stability of the composition is improved. The performance contradiction between the high calcium content and the vitamin stability is avoided, and the endophytic environmental adaptability of the composition is improved.

The invention belongs to the technical field of medicinal preparation processing, and particularly relates to oral liquid for supplementing calcium, vitamin D and vitamin K and a preparation method of the oral liquid. The fruit and vegetable powder is prepared from the following raw materials in parts by weight: 100 to 500 parts of calcium citrate, 0.2 to 2.5 parts of vitamin D3 emulsion, 0.4 to 5.5 parts of vitamin K2, 0 to 100 parts of casein phosphopeptides, 0.1 to 200 parts of fruit and vegetable powder, 0 to 5 parts of citric acid, 0 to 5 parts of malic acid, 0.1 to 400 parts of a sweetening agent, 0.01 to 10 parts of a thickening agent, 0.1 to 5 parts of an emulsifying agent, 0 to 2 parts of stevioside and 665 to 1395 parts of water. According to the invention, the vitamin D3 emulsion process is improved, the proper antioxidant is added, and the proper consistency is adjusted, so that the stability of the vitamin D3 in the oral liquid product is ensured, and the dosage form application range of the calcium supplement is enlarged.

The invention provides a composition. The composition is prepared from vitamin A, vitamin D, vitamin E, vitamin K and health-care food or food-acceptable auxiliary materials according to specific proportions and doses. The anti-osteoporosis health-care food has the advantages that the vitamin components have a synergistic effect in the aspect of anti-osteoporosis, and the anti-osteoporosis health-care food can increase bone mineral density and maintain bone mass. In addition, the composition disclosed by the invention can also be used for precise nutritional supplement of specific crowds.

The invention discloses color-improving high-fat compound feed for fancy carps and a preparation method of the color-improving high-fat compound feed, and belongs to the technical field of feed. The method is used for solving the technical problem that in the prior art, crude protein and pigment compositions in the color-increasing high-fat compound feed for the fancy carp are easily influenced by factors such as light, heat and pH. The color-improving high-fat compound feed for the fancy carp comprises a crude protein powder mixture, a grease expanding agent, a pigment compound, monocalcium phosphate, an antioxidant, choline, vitamin A and vitamin K. Mixing the spirulina, the astacin, the green algae and the xanthophyll to obtain a mixture; coating the mixture with an organic monomer butyl cyanoacrylate to prepare a pigment compound; the peony seed oil and the olive oil are used as wall materials to coat mixed core material powder composed of the fish meal, the soybean meal, the shrimp meal and the peanut meal, and the grease expanding agent is prepared. The prepared color-enhancing high-fat compound feed for the fancy carp has the effects of enhancing color enhancement, avoiding fat deposition of the fancy carp and balancing and enriching various nutrient elements.

The utility model relates to the field of feeding devices, in particular to a feeding device of a vitamin K drop colloid mill, which comprises an ingress pipe, a connecting pipe is arranged above the guide-in pipe, and a hopper is arranged above the connecting pipe. After the device is used for a period of time, the ingress pipe, the connecting pipe and the hopper are sequentially disassembled, the inner walls of the ingress pipe, the connecting pipe and the hopper are cleaned, then the ingress pipe, the connecting pipe and the hopper are sequentially assembled, and then the lower end of the ingress pipe is mounted on equipment, so that the device can be continuously used; through the method, material residues on the inner surfaces of all parts of the feeding device can be thoroughly removed, the residual materials are prevented from being mixed into new products in the next production process, so that the purity and the ingredient accuracy of the vitamin K drops are guaranteed, the products are prevented from being polluted or the quality is prevented from fluctuating, the breeding environment of bacteria and microorganisms can be reduced through the clean feeding device, and the production efficiency is improved. And the safety and the stability of the product can be ensured.

The invention relates to the technical field of fermentation, in particular to a protein composition for promoting calcium absorption and muscle synthesis and preparation and application thereof. The protein composition comprises the following components in parts by weight: 0.5-99 parts of yeast protein and 0.5-20 parts of a calcium source, the protein content in the yeast protein is more than or equal to 70%, and the zinc content in the yeast protein is more than or equal to 200mg / kg; in terms of the weight of the yeast protein, the content of serine in the yeast protein is larger than or equal to 50 mg / g, and / or the content of glutamic acid is larger than or equal to 110 mg / g, and / or the content of leucine is larger than or equal to 90 mg / g, and / or the content of isoleucine is larger than or equal to 55 mg / g, and / or the content of valine is larger than or equal to 50 mg / g, and / or the content of lysine is larger than or equal to 94 mg / g. The protein composition prepared by combining the yeast protein as a main raw material with the calcium source and nutritional ingredients such as the vitamin D, the vitamin K, the collagen or the casein phosphopeptides not only can promote absorption and utilization of calcium, but also can promote muscle synthesis and improve muscle quality, so that the requirement of collaborative health of muscles and bones is met.

The invention discloses a feed additive for rapidly improving metabolic syndrome of carnivorous aquatic animals. Every 1000g of the feed additive comprises the following components: 20 to 40g of tea polyphenol, 0.5 to 2g of nuciferine, 8 to 25g of ginkgetin, 3 to 8g of glycyrrhetinic acid, 0.5 to 1.5 g of sennoside, 5 to 10g of glutathione, 0.1 to 5g of ginsenoside, 0.1 to 0.5 g of bile acid, 1 to 5g of vitamin C, 0.1 to 0.5 g of vitamin E, 0.01 to 0.05 g of vitamin K and the balance of a carrier. The feed additive is prepared according to the principle of monarch, minister, assistant and guide, and can quickly improve the metabolic syndrome symptom of carnivorous aquatic animals. Experiments show that the additive can recover healthy appearance of the liver, regulate blood sugar and blood fat, enhance oxidation resistance and relieve inflammatory response within a short period of 3-4 days. The feed additive is safe, efficient, free of toxic and side effects, low in cost and suitable for various carnivorous aquatic animals such as micropterus salmoides, Chinese softshell turtles and sturgeons, an efficient and safe solution is provided for prevention and control of the metabolic syndrome of the aquatic animals, and the feed additive has good popularization value.

A method comprising the steps of: (a) assessing an expression level of at least one protein, selected from Table 1, 2 or 3 in a sample from a subject, where in the at least one protein may be selected from the list comprising: Beta-Ala-His dipeptidase, Apolipoprotein L1, Methanethiol oxidase, Vitamin K-dependent protein S, von Willebrand factor, Plasminogen, Selenoprotein P, Protein disulfide-isomerase A6 and Inter-alpha-trypsin inhibitor heavy chain H3, and (b) using the expression level to determine whether the subject has endometriosis.

The invention discloses a pharmaceutical composition for delaying senescence and resisting oxidation, and belongs to the technical field of biological medicine and health food. The composition comprises vitamin A, beta-carotene, vitamin complex B, vitamin C, vitamin D, vitamin E, vitamin k, macroelements including calcium, phosphorus, potassium and magnesium, microelements including zinc, selenium, iron, chromium, copper, molybdenum, iodine, fluorine and manganese, traditional Chinese medicines including ginseng, astragalus membranaceus, fructus lycii and radix polygoni multiflori preparata, and condition essential nutrient nucleic acid. The bioactive components comprise lycopene, tea polyphenol, taurine, lutein, lutein fat, zeaxanthin, chlorophyll and the like; is mainly suitable for middle-aged and elderly people; the composition eliminates multiple factors causing aging from multiple systems, multiple links and multiple targets, can significantly delay aging, has health-care and tonifying effects such as oxidation resistance, and can improve the life quality of middle-aged and elderly people while delaying aging; the composition has no incompatibility, and does not generate any toxic or side effect after being taken for a long time.

The invention relates to the technical field of lamb feeding, and particularly discloses a feed for feeding lambs in an alpine pasturing area and a feeding method of the lambs. Comprising the following raw materials in parts by weight: 30-50 parts of oat grass, 20-30 parts of alfalfa, 10-15 parts of highland barley powder, 5-10 parts of soybean meal, 3-8 parts of flaxseed cakes, 1-3 parts of calcium hydrophosphate, 0.5-2 parts of mountain flour, 0.3-0.8 part of table salt, 0.1-0.3 part of compound vitamins, 0.1-0.3 part of a trace element premix and 1-3 parts of a digestion promoting additive, the weight ratio of the vitamin A to the vitamin D to the vitamin E to the vitamin K is 5: 2: 3: 1. According to the feed for raising the lambs in the high and cold pasturing area and the raising method thereof, nutritional ingredients such as protein, energy, vitamins and minerals are comprehensively covered, the growth requirements of the lambs in the high and cold environment are met, dyspepsia can be reduced, and the preparation method of the feed is scientific.

The present embodiments are directed to compositions of quinones and / or quinols, such as, but not limited to, ubiquinone and / or ubiquinol, vitamin E quinone and / or vitamin E quinol, vitamin K quinone and / or vitamin K quinol, menaquinones and / or menaquinols, and pyrroloquinoline quinone and / or pyrroloquinoline quinol, and methods for preparations and use thereof. The present embodiments are also directed to compositions of reduced forms of curcuminoid and methods for preparations and use thereof.

The invention provides a micro-fat calcium supplement carrier, which is prepared from the following raw materials in parts by weight: 30 to 35 parts of standard index calcium, 1 to 5 parts of chondroitin, 1 to 5 parts of glucosamine, 8 to 12 parts of pure camel milk, 0.7 part of vitamin D, 2 to 70.3 parts of vitamin K, 1 to 3 parts of phospholipid complex and 8 to 10 parts of excipient. According to the invention, standard calcium, chondroitin, glucosamine, pure camel milk, vitamin D, vitamin K2-7, a phospholipid complex and an excipient are organically mixed by adopting a liposome carrier technology, so that the digestion and absorption of calcium in a body and the distribution of calcium in a specific region are effectively improved, and further the effects of rapid bone growth, increase of bone length (promotion of height increase) and increase of bone density are achieved; the health-care food has the health-care functions of reducing the fracture probability, preventing tooth decay, reducing the death rate of cardiovascular diseases and the like, so that the calcium absorption rate is remarkably improved and reaches up to 95%.

1. Name of the product in this design: Packaging box and bottle kit (Nortrand brand calcium, vitamin D and vitamin K tablets). 2. Application of this design: Kit 1 is for packaging boxes, and Kit 2 is for packaging bottles. 3. The key design features of this product are the combination of shape and pattern. 4. The picture or photo that best illustrates the design points: the main view of Suite 1.

The invention discloses a pharmaceutical composition for preventing birth defects and improving memory, and belongs to the technical field of biological medicine and health food. The composition comprises vitamin A, beta-carotene, vitamin complex B, vitamin C, vitamin D, vitamin E, vitamin k, macroelements including calcium, phosphorus, potassium and magnesium and microelements including zinc, selenium, iron, chromium, copper, molybdenum, iodine, fluorine and manganese, traditional Chinese medicines including glossy privet fruit, astragalus membranaceus, fructus lycii, semen cuscutae and nucleic acid, and bioactive components including lutein, lutein fat, zeaxanthin, grape seed extract, chlorophyll and taurine. The device is mainly used for pre-pregnancy preparation of pregnant women, dosages thereof, pregnant women and wet nurses. The composition eliminates various factors causing birth defects from multiple systems, multiple links and multiple targets, can significantly reduce the total occurrence rate of birth defects, has the effect of improving memory, is beneficial to the health of parents and children, has no incompatibility, and does not generate any toxic or side effect after being taken for a long time.

The invention provides a postbiotic composition for promoting secretion of endogenous growth hormone, and relates to the technical field of biology. The metagen composition comprises metagen, vitamin D, vitamin K, calcium and colostrum basic protein, wherein the metagen is obtained by fermenting a culture medium containing a traditional Chinese medicine additive through a probiotic agent. Through fermentation of the probiotic agent, macromolecular substances in the traditional Chinese medicine additive can be converted into micromolecular substances, the bioavailability is improved, and the micromolecular substances are converted into components for promoting secretion of endogenous growth hormones, so that the growth promoting effect is achieved. A test result shows that the postbiotic composition can remarkably promote secretion of endogenous growth hormone and improve the level of the endogenous growth hormone.

To provide compositions for protecting retina which can protect retinal pigment epithelial cells from the damage of active oxygen more effectively and inhibit retinopathy.SOLUTION: A composition for protecting retina contains as active ingredients astaxanthin and at least one ingredient selected from the group consisting of Ipomoea batatas young-leaf processed materials, Pueraria montana flower processed materials, Vaccinium myrtillus processed materials, gallic acid, glutamic acid, histidine, methionine, serine, tyrosine, valine, vitamin B6, vitamin B12, vitamin C, vitamin D3, vitamin K, a calcium compound, a zinc compound, an iron compound, a molybdenum compound, a chromium compound, and shellac.SELECTED DRAWING: Figure 1

The invention discloses application of dihydromyricetin as a regulator for reducing the content of vitamin K, and belongs to the field of biological medicine. The invention discloses dihydromyricetin which can be used for preparing a product for reducing the content of vitamin K in blood. The dihydromyricetin disclosed by the invention can up-regulate expression of an NQO1 gene and protein and promote conversion of vitamin K into a vitamin K precursor substance, so that the content of vitamin K in blood is reduced.

The application provides a child formula milk for promoting bone development and a preparation method thereof, and relates to the technical field of dairy products.The child formula milk for promoting bone development comprises the following raw materials in mass parts: raw cow milk 970-999 parts, a composite vitamin 0.05-1 part, a mineral 0.1-1.5 parts, colostrum basic protein 0.1-1 part and 2'-fucosyllactose 0.1-2 parts; the composite vitamin contains vitamin K, and the mass ratio of 2'-fucosyllactose to the composite vitamin is 0.5:1-20:1; the mass ratio of colostrum basic protein:2'-fucosyllactose: vitamin K: mineral is 1:(1-10):(0.1-0.5):(0.5-10). The child formula milk for promoting bone development can effectively promote bone development and improve product stability through specific content matching of each raw material component.

The present invention relates to a composition having the effects of nourishing blood and replenishing qi and reducing weight. The raw materials for preparation include the following components: hawthorn, cassia seed, kudzu root, cinnamon bark, grape, salvia miltiorrhiza, psoralea corylifolia, wolfberry, eucommia bark, ginseng, vitamin A, vitamin B1, vitamin K, vitamin U, and folic acid. The rational combination of hawthorn, cassia seed, and kudzu root reduces the body's absorption and utilization of lipids. The composition of the present invention achieves a good weight loss effect, while also strengthening the body's foundation and nourishing the vital energy, consolidating and conditioning the body. On this basis, multiple vitamins are added to provide the body with vitamin intake in daily life and maintain the body's nutritional balance. The composition of the present invention can be directly ground into powder to obtain a finished product, or it can be extracted by a suitable method to obtain a better therapeutic effect.

The invention provides a composition. The composition is prepared from vitamin D, vitamin B6, folic acid substances, vitamin K and acceptable auxiliary materials. The composition has the advantages that the composition has a synergistic effect, can regulate fat metabolism and maintain the healthy level of blood fat, is free of toxic and side effects, is good in safety, can be eaten for a long time, and is easily accepted by people. In addition, the multi-component compound form of the product can obviously improve the taking compliance of users, and the total use cost is saved.

The application discloses a composition containing fat-soluble vitamins, and is characterized in that the composition comprises the following components: a poorly soluble calcium salt, fat-soluble vitamins, vegetable oil, an emulsifier and water; the mass percentage of the poorly soluble calcium salt in the composition is 12-35%; the solubility of the poorly soluble calcium salt is less than 1 g / 100 mL, and the particle size is 800-2000 mesh; the fat-soluble vitamins comprise at least one of vitamin D, vitamin K, vitamin A and vitamin E, and the mass percentage of the fat-soluble vitamins in the composition is 0.00002-1.5%. The oil-in-water structure formed by the fat-soluble vitamins in the composition is more stable, the fat-soluble vitamins are more stable in the liquid preparation and are not easy to degrade, and the fat-soluble vitamins have a better effect. Meanwhile, the composition can promote the cell uptake rate of calcium, promote the absorption of calcium and improve the nutritional value of the composition.

This invention provides a probiotic, a probiotic composition, and their applications, all possessing the functions of calcium ion enrichment and vitamin K synthesis. This invention belongs to the field of microbial technology. The probiotic provided by this invention is *Lactobacillus bulgaricus* subsp. Lactobacillus delbrueckii subsp. bulgaricus NWP-101 or Pyrococcus lactis ( Pediococcus acidilactici NWP-299 has the advantages of efficient calcium enrichment, high vitamin K production and excellent probiotic properties. It can be used to prepare probiotic preparations, functional foods, health foods or dietary supplements to prevent or improve osteoporosis and increase bone density.

The invention discloses a pharmaceutical composition for delaying senescence and resisting oxidation, and belongs to the technical field of biological medicine and health food. The composition comprises vitamin A, beta-carotene, vitamin complex B, vitamin C, vitamin D, vitamin E, vitamin k, macroelements including calcium, phosphorus, potassium and magnesium, microelements including zinc, selenium, iron, chromium, copper, molybdenum, iodine, fluorine and manganese, traditional Chinese medicines including ginseng, astragalus membranaceus, schisandra chinensis and radix polygoni multiflori preparata, and condition essential nutrient nucleic acid. The bioactive components comprise lycopene, tea polyphenol, taurine, lutein, lutein fat, zeaxanthin, chlorophyll and the like; is mainly suitable for middle-aged and elderly people; the composition eliminates multiple factors causing aging from multiple systems, multiple links and multiple targets, can significantly delay aging, has health-care and tonifying effects such as oxidation resistance, and can improve the life quality of middle-aged and elderly people while delaying aging; the composition has no incompatibility, and does not generate any toxic or side effect after being taken for a long time.

The invention belongs to the technical field of biological medicine, and discloses application of an active substance in preparation of a VKOR inhibitor and / or a vitamin K antagonist and an anticoagulant drug. The invention provides application of an active substance shown in a formula (1) or pharmaceutically acceptable salt thereof in preparation of a vitamin K epoxide reductase inhibitor. The active substance has VKOR inhibitory activity, can prevent liver from synthesizing blood coagulation factors and activating anticoagulant factors by blocking reduction of oxidized vitamin K and inhibiting circulation of vitamin K, has potential anticoagulant activity, and has the advantages of mild anticoagulant effect, low probability of occurrence of adverse hemorrhage events, good anticoagulant effect, high safety and the like. The compound has a good application prospect in preparation of anticoagulants and / or medicines for treating thromboembolic diseases.

The invention discloses a detection method and a detection kit for five fat-soluble vitamins in dried blood spots, and the detection method comprises the following steps: step 1, taking a dried blood spot sample, adding an extracting solution and an internal standard mixed solution, carrying out vortex treatment, ultrasonic treatment and centrifugation, and taking a supernatant; wherein the internal standard mixed solution comprises a deuterated vitamin A, a deuterated 25-hydroxy vitamin D2, a deuterated 25-hydroxy vitamin D3, a deuterated vitamin K and a deuterated vitamin E; and 2, carrying out liquid chromatography-tandem mass spectrometry sample injection detection on the supernatant. The method can effectively solve the problem of cross interference of 25 (OH) D3 and 3-epi-25 (OH) D3, improves the accuracy of 25 (OH) D3, and is of great significance to infant sample detection, clinical disease confirmation, body endocrine state monitoring and the like. The method uses short gradient, and has the advantages of short detection time, high detection efficiency, high accuracy, strong sensitivity and the like compared with a single sample of many products of the same type.

1. Name of the product of this design: Packaging box (Calcium Vitamin D Vitamin K Chewable Tablets). 2. Purpose of this design product: This design is a product packaging box. 3. The key design point of this design product lies in the combination of shape and pattern. 4. The picture or photo that best illustrates the design points: three-dimensional picture.

The present invention refers to food compositions comprising selenium, preferably in an amount of at least 4 μg / g, and a set of different ingredients selected from retinyl palmitate, calcitriol (1,25(OH)2 Vitamin D3), phylloquinone (phytomenadione, Vitamin K1), tocopherol (preferably a-tocopherol), or ubiquinol. The invention particularly refers to chocolate bars comprising selenium and the set of different ingredients. Consumption of the food compositions of the invention can reverse, reduce or slow signs of aging in a subject. The invention also relates to methods of producing cacao fruits, cacao beans, cacao mass, and cacao powder with an increased selenium content.

This invention relates to a selenium-containing compound vitamin chewable tablet and its preparation method, comprising the following raw materials in parts by weight: 10-16 parts selenium-enriched yeast, 25-35 parts L-ascorbic acid, 0.5-1 part vitamin K, 10-20 parts sorbitol, 1-3 parts DL-α-tocopherol acetate, 3-8 parts sodium octenyl succinate starch, 1-5 parts acetylated distarch adipate, 0.7-1.2 parts magnesium stearate, 0.3-0.5 parts potassium citrate, 0.04-0.07 parts steviol glycosides, and 5-10 parts modified silica. This invention improves the crispness and palatability of the chewable tablet by adding acetylated distarch adipate and sodium octenyl succinate starch; the addition of modified silica effectively reduces vitamin attenuation and improves the stability of the components.