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Nutrition composition beneficial to depression patient health

A technology of composition and nutritional supplement, applied in the field of health food or pharmaceutical composition, nutritional supplement

Active Publication Date: 2017-06-20
SHENZHEN AUSA PHARM CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many multivitamin products on the market, but there is no vitamin supplement product for people with depression or depression tendency. This invention is based on precision nutrition and will solve this problem

Method used

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  • Nutrition composition beneficial to depression patient health
  • Nutrition composition beneficial to depression patient health
  • Nutrition composition beneficial to depression patient health

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1: tablet preparation (1000 pieces amount) of nutritional supplement of the present invention

[0036] formula:

[0037]

[0038] Preparation method: take povidone K30 and prepare an adhesive with 50% ethanol solution, then add vitamin K into the adhesive and stir evenly, and set aside. Extra Vitamin B 12 , folic acid, sucralose and pregelatinized starch are mixed and sieved, then milk essence, carboxymethyl starch sodium and dextrin are added to mix, and the prepared soft material containing vitamin K binder is added, granulated with a 24-mesh sieve, Dry at 55°C for 2 hours, sieve through a 24-mesh sieve, add magnesium stearate, mix, and tablet. The coating premix is ​​formulated into a solution, and the plain tablet is coated to obtain the tablet of the nutritional supplement of the present invention.

Embodiment 2

[0039] Embodiment 2: the soft capsule preparation (1000 amount) of health food of the present invention

[0040] formula:

[0041]

[0042] Preparation method: add beeswax to soybean oil, heat at 50°C to dissolve the beeswax, place it at room temperature, take vitamin K, 5-methyltetrahydrofolate, and vitamin B 12 Add soybean oil to make a suspension and set aside. In addition, gelatin, purified water, caramel color, and parabens are prepared into a glue solution, and the prepared suspension is pressed into pills by a pill press to make soft capsules. After shaping, pill washing and drying, it is prepared Obtain the soft capsule of health food of the present invention.

Embodiment 3

[0043] Embodiment 3: preparation of pharmaceutical composition hard capsules of the present invention (1000 grains amount)

[0044] formula:

[0045]

[0046] Preparation method: mix folic acid with 20% microcrystalline cellulose, sieve, then add vitamin K and vitamin B 12 Mix the obtained raw material mixture with the remaining amount of microcrystalline cellulose in equal increments, then add lactose and magnesium stearate to mix, then use a full-automatic capsule filling machine to fill, and after polishing, obtain the capsules of the present invention. The hard capsule of above-mentioned pharmaceutical composition.

[0047] The pharmaceutical composition prepared in Example 3 was taken for safety toxicology evaluation and pharmacodynamic test.

[0048] Acute Toxicity: Get the contents of the capsules prepared in Example 3, give 20 rats (half male and half female) at a dose of 5g / kg, give them by intragastric administration at a volume of 40mL / kg, administer once, and ...

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Abstract

The invention provides nutritious supplementary, health-care food or pharmaceutical composition and disclosed nutrition composition which has an accurate nutritional supplement implementing, health-care or supportive therapeutic effect on depression people or people with depression trend. The composition is prepared from 100mu g to 2mg of folic acid, 0.5 to 200mu g of vitamin B12, 20mu g to 100mg of vitamin K and the defined amount of food or medicine acceptable auxiliary materials.

Description

technical field [0001] The present invention relates to a nutritional supplement, a health food or a pharmaceutical composition, more precisely, the present invention relates to a nutritional supplement, a health food or a pharmaceutical composition that provides precise nutritional supplementation and sedation for depression and depression-prone patients . Background technique [0002] The pressure of work and life in modern society is increasing. Many times people are on the verge of anxiety and depression. In severe cases, depression, anxiety neurosis, mania, schizophrenia and other mental diseases occur. Depression is a mental and emotional disorder with abnormal behavior and low mood as the main symptoms. Depression can affect or even cause damage to people's digestion, immunity, nervous system and other skills, and the disease has high Morbidity, refractory and high recurrence rate and other characteristics. It seriously plagues people's normal work, study and life, ...

Claims

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Application Information

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IPC IPC(8): A23L33/15A61K31/519A61K31/714A61K31/05A61P25/24A61P25/22A61P25/18A61P25/00A61P25/08
CPCA23V2002/00A61K31/05A61K31/519A61K31/714A61K2300/00A23V2250/7056A23V2250/706A23V2250/714A23V2250/7142A23V2250/7144A23V2250/7146A23V2200/322
Inventor 白洁张磊王滨燕陈平徐希平
Owner SHENZHEN AUSA PHARM CO LTD
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