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Traditional Chinese medicine composition

A technology of composition and natural medicine, which is applied in the direction of drug combination, antineoplastic drug, pharmaceutical formula, etc., to achieve the effect of good side effects, increased inhibitory effect, and obvious synergistic effects

Inactive Publication Date: 2013-07-31
张宗升
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Traditional Chinese medicine composition
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Comparison scheme
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Embodiment approach

[0030] The first step: preparation of various extracts

[0031] (1) Preparation of decocted concentrated extract of tangerine peel and myrobalan

[0032] Take tangerine peel and myrobalan according to the compatibility ratio of 1:1 or 1-4:1, soak in 10 times the amount of distilled water for 1 hour, heat and decoct on an electric stove with asbestos net for 1 hour, filter with silk cloth, save the filtrate, and recycle the dregs. Add 6 times of distilled water, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate to a small volume, filter with an ultrafiltration membrane, and dry under reduced pressure at 70°C for 36 hours in a vacuum drying oven to obtain a brown-yellow powder.

[0033] (2) Preparation of Nobiletin

[0034] Take the dried tangerine peel medicinal material, coarsely crush, sieve, reflux and extract 20 times the amount of petroleum ether for 5 times, 6 hours each time, combine the petroleum ether extract, recover the petroleum ...

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Abstract

The invention relates to a natural pharmaceutical composition, preparation method thereof and the usage in preparing an attenuated synergistic medicament in cancer chemotherapy, wherein the natural pharmaceutical composition consists of decoction condensed extract product of dried orange peel and terminalia, nobiletin and 70% ethanol extract product of terminalia in a proportion of (2-6):(3-6):(5-8). TheThe composition has good curative effect to cancer chemotherapy related diarrhoea and increases effect to cancer chemotherapy.

Description

technical field [0001] The present invention relates to a kind of natural medicine composition, more specifically relate to a kind of natural medicine composition that is made up of tangerine peel chebula decoction concentrated extract, nobiletin and chebula 70% ethanol extract, the natural medicine composition The preparation method and the application of the natural medicine composition in the preparation of medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs, whether used alone or in combination, can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called chemot...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61P35/00A61P1/12
Inventor 张宗升
Owner 张宗升
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