Medicine for treating chronic gastritis, gastric ulcer and/or duodenal ulcer and preparation method thereof

A technology of drugs and medicinal materials, applied in the field of drugs and preparations for the treatment of chronic gastritis, gastric ulcer and/or duodenal ulcer, capable of solving problems such as liver and kidney function damage

Active Publication Date: 2013-10-23
吉林一正药业集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

And long-term use of antibiotics can cause nausea, vomiting and even liver and kidney damage

Method used

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  • Medicine for treating chronic gastritis, gastric ulcer and/or duodenal ulcer and preparation method thereof
  • Medicine for treating chronic gastritis, gastric ulcer and/or duodenal ulcer and preparation method thereof
  • Medicine for treating chronic gastritis, gastric ulcer and/or duodenal ulcer and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1, prepare the capsule of Chinese medicine composition

[0029] Take 80g tangerine peel (tangerine peel), 80g Angelica dahurica, 80g rhubarb, 80g kudzu root, 80g gardenia, 32g amomum and 32g licorice Qiwei purified medicinal materials, decoct and extract the above medicinal materials twice, and the amount of water added is the total mass of medicinal materials 8 times and 6 times of that, the extraction time is 3 hours and 2 hours respectively, after each extraction, filter, and the combined filtrate is concentrated to a clear paste with a relative density of 1.10 (measured at 70°C), let it cool, and add 80% ( volume percentage content) of ethanol to make the alcohol content reach 50% (volume percentage content), stir evenly, let stand for 48 hours, take the supernatant and reclaim the ethanol to the utmost, and the medicinal solution is concentrated to a relative density of 1.20 (measured at 70°C ) thick paste, dried, pulverized, crossed 80-120 mesh sieve, a...

Embodiment 2

[0030] Embodiment 2, prepare the capsule of Chinese medicine composition

[0031]Take 60g tangerine peel (tangerine peel), 80g Angelica dahurica, 60g rhubarb, 50g kudzu root, 70g gardenia, 25g amomum and 30g licorice Qiwei. hour, after the extraction is complete, filter, and the filtrate is concentrated to a clear paste with a relative density of 1.15 (measured at 70° C.), let it cool, and add 90% (volume percent) ethanol to make the alcohol content reach 60% (volume percent) content), stir evenly, let stand for 24 hours, take the supernatant to recover ethanol to the utmost, concentrate the liquid medicine to a thick paste with a relative density of 1.25 (measured at 70°C), dry, pulverize, pass through a 80-120 mesh sieve, and add the obtained 0.08 times of starch and 0.01 times of talcum powder by weight of the powder, mixed evenly, granulated with ethanol, dried, and packed into capsules to obtain 72 capsules.

Embodiment 3

[0032] Embodiment 3, prepare the capsule of Chinese medicine composition

[0033] Take 20g tangerine peel (tangerine peel), 50g Angelica dahurica, 20g rhubarb, 80g kudzu root, 40g gardenia, 4g amomum and 20g licorice Qiwei. 8 times and 6 times, the extraction time is 3 hours and 2 hours respectively, after each extraction is completed, filter, and the combined filtrate is concentrated to a clear paste with a relative density of 1.15 (measured at 70°C), let it cool, and add 70% (volume percentage content) of ethanol to make the alcohol content reach 40% (volume percentage content), stir evenly, leave standstill for 12 hours, take the supernatant and reclaim the ethanol to the utmost, and the medicinal solution is concentrated to a relative density of 1.35 (measured at 70°C) The thick ointment is dried, pulverized, and passed through a 80-120 mesh sieve to obtain a traditional Chinese medicine composition powder. Add starch with the same quality as the obtained medicinal powder...

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Abstract

The invention discloses a pharmaceutical composition for treating chronic gastritis, gastric ulcer and/or duodenal ulcer and a preparation method thereof. The pharmaceutical composition comprises the following raw materials in parts by weight: 20-80 parts of pericarpium citri reticulatae (orange peel), 20-80 parts of radix angelicae, 20-80 parts of rheum officinale, 20-80 parts of the root of kudzu vine, 20-80 parts of jasmine, 4-36 parts of jasmine and 5-35 parts of liquorice. The method for preparing the pharmaceutical composition comprises the following steps of: adding water to the raw materials, decocting, extracting, collecting the filtrate; concentrating the filtrate to clear cream; cooling; then, adding 60-95% ethanol to the clear cream so that the content of ethanol reaches 30-70%; uniformly stirring; standing still; taking supernate; recovering all ethanol to obtain thick paste; drying and smashing to obtain medicine powder which is prepared into capsules or troches and the like. Clinical experiments show that the pharmaceutical composition has the effects of clearing away heat-fire, tonifying spleen and qi, relieving swelling and pain and stopping bleeding and is used for treating chronic gastritis, gastric ulcer and duodenal ulcer.

Description

technical field [0001] The invention relates to a medicine for treating chronic gastritis, gastric ulcer and / or duodenal ulcer and a preparation method thereof. Background technique [0002] Gastritis refers to inflammation of the gastric mucosa caused by various etiologies. Acute and chronic are divided into two categories according to the acute onset and the length of the course of the disease. According to the severity of mucosal damage, gastritis can be divided into erosive gastritis and non-erosive gastritis, and can also be classified according to the location of the stomach (such as cardia, gastric body, gastric antrum). [0003] Acute gastritis refers to an acute inflammatory reaction of the gastric mucosa caused by various reasons. There are many reasons for acute gastritis, including chemical reasons, physical reasons, and toxin reasons / stress states. Patients with acute gastritis often have epigastric pain, nausea, belching, vomiting, and loss of appetite. The...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61P1/04
Inventor 于春江
Owner 吉林一正药业集团有限公司
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