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Tea fungus synthesized bacterial cellulose pressure sore dressing as well as preparation method and application thereof

A technology of bacterial cellulose and bacterial cellulose film is applied to bacterial cellulose pressure ulcer dressings synthesized by kombucha and the fields of preparation and use thereof to achieve good water holding capacity, promote wound healing, and increase secondary water absorption and air permeability. Effect

Inactive Publication Date: 2013-12-04
NANTONG UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

There is no relevant report on the use of bacterial cellulose synthesized by kombucha fungus in medical pressure ulcer dressings

Method used

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  • Tea fungus synthesized bacterial cellulose pressure sore dressing as well as preparation method and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Preparation of KBC: It is prepared by tea fermentation method.

[0022] (1) In terms of weight percentage, assuming that in a medium system with a total volume of 1L, add 0.5~2% black tea and 10~20% sucrose into a beaker containing 500mL double distilled water, and boil for 5~15 minutes After cooling to room temperature;

[0023] (2) After fully filtering the solution in the above step (1) to remove tea residue, add 0.5~1% and 0.5~1% (v / v), 0.5~1% and 0.5~1% yeast, ethanol, carboxymethyl chitosan and peptone, fully stirred to dissolve;

[0024] (3) Adjust the total volume and pH value of the solution in the above step (2) to 1L and 4.5~5.5 respectively through double distilled water and 1~5% acetic acid solution, and pasteurize it for 20~30 minutes ;

[0025] (4) Pour the freshly prepared basal medium in the above step (3) into a clean shallow dish covered with 3~5 layers of clean gauze and ventilated (or other suitable containers such as flasks, etc.), add the moth...

Embodiment 2

[0033] In step (1), 0.5-2% black tea and 10-20% sucrose are respectively replaced with 0.5-2% green tea and 10-20% glucose, and the rest are the same as in Example 1.

Embodiment 3

[0035] In step (1), 0.5-2% of black tea and 10-20% of sucrose are respectively replaced with black tea and green tea mixed additives with a total content of 0.5-2% and sucrose and glucose mixed additives with a total content of 10-20%. All the other are with embodiment 1.

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Abstract

The invention discloses a tea fungus synthesized bacterial cellulose pressure sore dressing as well as a preparation method and the application thereof. The tea fungus synthesized bacterial cellulose pressure sore dressing is a tea fungus synthesized bacterial cellulose membrane, and the cellulose component is mainly formed by secretion and synthesis of tea fungus strains in the fermentation culturing process in a sugar tea culture medium containing carboxymethyl chitosan; the water absorption rate of the dressing is 89-94.3%, the porosity is 85-91.2%, and the water vapor transmission rate is between 1,383.5 g.m<-2>.d<-1> and 1,486.5 g.m<-2>.d<-1>. According to the invention, since the nano bacterial cellulose pressure sore dressing is prepared with a sugar tea fermentation method by adopting the tea fungus, the method for synthesis of bacterial cellulose has the advantages of low cost, low environment requirement for synthesis sites and simple technical requirements; the nano bacterial cellulose material has favorable biosecurity and histocompatibility, which cannot cause stimulation and sensitization to a wound surface, and is conducive to the promotion of wound healing.

Description

technical field [0001] The invention relates to a bacterial cellulose pressure sore dressing synthesized by kombucha fungus, a preparation method and application thereof. Background technique [0002] Pressure sores are localized injuries to the skin, muscles, and subcutaneous tissue caused by pressure, shear, or friction, often over bony prominences. The incidence of pressure sores is high and the recovery is slow. If the treatment and care are not appropriate, it can lead to muscle and bone necrosis and even systemic infection, which can threaten the lives of patients in severe cases. Clinically, various dressings are mainly used to cover and protect the wound and provide a microenvironment conducive to wound healing and recovery as soon as possible. Although there are many types of pressure ulcer dressings currently available, they have their corresponding limitations. Such as ordinary gauze dressing, although it has the characteristics of absorbing exudate, protecting ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/42C12P19/04
Inventor 陈宏林朱昌来贺小琴沈王琴李峰刘鹏
Owner NANTONG UNIVERSITY
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