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Preparation process of granules for protecting liver and promoting bile flow

A preparation process, liver-protecting and gallbladder-protecting technology, applied in the field of preparation of liver-protecting and gallbladder granules, to achieve the effects of ensuring full absorption, improving concentration efficiency, and preventing oxidation

Inactive Publication Date: 2013-12-18
HENAN UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For thousands of years, the small-leaved lilac has been used to make tea and drink among the people in western Henan. It can be used to treat hepatitis, cirrhosis, and liver cancer for a long time. Therefore, this plant has not been developed as a folk raw material medicine.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0017] A preparation process of liver-protecting and choleretic granules, comprising the following steps:

[0018] Step 1, preparation of lilac flower extract extractum

[0019] Get lilac lobular raw material, remove impurities, and keep the leaves with a length of no more than 2 cm to obtain lilac lobular raw material medicine, and set aside;

[0020] Put the obtained lilac flower raw material medicine in a distiller for steam distillation, after distillation for 3-4 hours, take it out, put the distilled lilac flower raw material medicine in an oven, and bake it under the condition of 60-70°C Bake for 2-4 hours, take it out after the end of baking, and obtain the raw material medicine powder residue, then place the raw material medicine powder residue in a sealed container, and add edible alcohol with a mass concentration of 70% in the sealed container, and the addition of edible alcohol is higher than 3-5cm of raw material drug powder residue, then sealed and soaked for 2d,...

Embodiment 1

[0028] A preparation process of liver-protecting and gallbladder granules, comprising the following steps:

[0029] Step 1, preparation of lilac flower extract extractum

[0030] Get lilac lobular raw material, remove impurities, and keep the leaves with a length of no more than 2 cm to obtain lilac lobular raw material medicine, and set aside;

[0031] Put the obtained lilac flower raw material medicine in a distiller for steam distillation, after distillation for 3 hours, take it out, place the distilled lilac flower raw material medicine in an oven, bake it at 60°C for 2 hours, and bake it for 2 hours. Take it out after baking to obtain the raw material drug powder residue, then place the raw material drug powder residue in a sealed container, and add edible alcohol with a mass concentration of 70% in the sealed container, the amount of edible alcohol is 3-5cm higher than the raw material drug powder residue place, then first seal and soak for 2 days, then perform ultrason...

Embodiment 2

[0038] A preparation process of Baoganlidan granules, comprising the following steps:

[0039] Step 1, the preparation of clove flower extract extract

[0040] Get the raw material of lilac lobularis, remove impurities, and keep the leaves with a length of no more than 2 cm to obtain the raw material medicine of lilac lilac, for use;

[0041] First, place the obtained lilac raw material in a distiller for steam distillation, and after distillation for 4 hours, take it out, place the distilled lilac raw material in an oven, bake it at 70°C for 4 hours, and bake it for 4 hours. After baking, take it out to obtain the raw material powder residue, then place the API powder residue in a sealed container, and add edible alcohol with a mass concentration of 70% to the sealed container, and the amount of edible alcohol added is 3-5cm higher than the API powder residue place, then sealed and soaked for 2d, then ultrasonic-assisted extraction was performed for 12h, and after the extrac...

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Abstract

The invention mainly relates to a preparation process of granules for protecting liver and promoting bile flow. The preparation process comprises the following steps of: 1, distilling raw sytingamicrophylla through water vapor; drying; circularly performing sealing and soaking and ultrasonic-assisted extraction twice; performing alcohol precipitation to the obtained sytingamicrophylla extracting solution at low temperature; carrying out pressure-reduced concentration to obtain a sytingamicrophylla extractive concrete to stand by service for later use; and 2, adding starch and dextrin to the sytingamicrophylla extractive concrete obtained in step 1 based on the weight ratio of (1-1.2): (1.5-2.0): (0.5-1.0); preparing a soft material; granulating; and straightening to accomplish the preparation of the granules. The preparation process provided by the invention is mild; the bioavailability is high; the granules for protecting liver and promoting bile flow, prepared by the process, are high in content of pharmaceutical ingredients, show have remarkable, stable and long-term effect, and have no toxic and side effects.

Description

technical field [0001] The invention relates to the field of preparation of traditional Chinese medicines, in particular to a preparation process of liver-protecting and gallbladder-reducing granules. Background technique [0002] Small-leaved cloves ( Syringa pubescens , Turca), also Oleaceae (oleaceac) syringa (syringa) plants, shrubs, also known as hair (leaf) cloves, sparrow flowers, Qiaoling flowers, produced in Henan, Hebei, Shaanxi and other provinces, mainly distributed in our province In the Funiu Mountains and Taihang Mountains. After searching Chinese traditional medicine literature and consulting a large number of literature, the medicinal use of this plant has not been found to be documented, and the systematic research on chemical components has been the report of our research results for many years. Our research has shown that the main medicinal components of Lilac oleifera are secoiridoid glycosides; this type of compound is the main effective ingredient ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/63A61K9/16A61P1/16
Inventor 尹卫平李月华刘普付改玲张延萍张宏丽曹冉冉李海迪
Owner HENAN UNIV OF SCI & TECH
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