74 results about "Hydrocholeretics" patented technology

The invention discloses a health-care beverage containing purslane. The beverage components are: 10-20% purslane plant extract, 0-0.025% sucrose, 0-0.03% acesulfame potassium, and maltose in weight percent Alcohol 0-10%, erythritol 0-10%, the balance is water. Wherein, the purslane plant extract is prepared by extracting the raw material of purslane with water, and the amount of water used is 5-10 times of the weight of the raw material of purslane. This health drink has broad-spectrum antibacterial, heat-clearing and detoxifying, liver-clearing and gallbladder-clearing, cooling blood and anti-inflammation, can prevent and treat summer heat, and has the effects of lowering fat, blood sugar, and blood pressure, and can prevent fatty liver, diabetes, high blood pressure, and coronary heart disease. It can be taken as a health product for a long time, and it can also prevent and fight cancer and prolong life.

The invention belongs to the technical field of medicine and food homologous formula and new resource food and particularly provides a medical formula food or specific medical formula food or non-specific medical formula food eaten by patients suffering from hepatic encephalopathy. According to the formula, according to the requirements of the General Rule for Special medical Purpose Formula Food and in combination of the constitutive characters of patients suffering from hepatic encephalopathy, various medicine and food homologous Chinese herbs are in reasonable compatibility according to the traditional Chinese medicine essence theory, medicine and food homologous traditional Chinese medicine extract essence extracted with a semi-bionic extracting method, various microencapsulated probiotics, oligopeptide extracted through biological enzymolysis, prebiotics, amino acid, carbohydrate, grease with the health-care function, various vitamins and mineral substances are mixed together and subjected to other processes, and the medical formula food is prepared. The medical formula food can serve as a single nutrition source to meet the nutrition needs of patients suffering from hepatic encephalopathy, and further performs the effects of strengthening the spleen and tonifying the lung, benefiting the bile and protecting the liver, nourishing yin and the liver, nourishing the liver and relieving pain, and boosting immunity.

The invention provides an artificial bear bile. The formula of the artificial bear bile comprises the following ingredients by mass percent: 35-48 of tauroursodeoxycholic acid, 50-63 of mixed choline, 1-3 of amino acid and 0.5-1 of trace element, wherein the mixed choline is an avian bile or a mixture of a plurality of avian biles and one or a mixture of a plurality of ox bile, sheep bile, rabbit bile and dog bile. The whole pharmacological tests prove that the artificial bear bile powder has the pharmacological functions which are similar to natural bear bile in the aspects of analgesia, sedation, convulsion prevention, inflammatory prevention, liver and gallbladder protection and the like, and can be used for completely substituting for the natural bear bile, the industrial production can be realized; and moreover, the price of the artificial bear bile is lower than that of the natural (drainage) bear bile, so the artificial bear bile is easily accepted. In addition, the molecular pharmacology also proves that the artificial bear bile has the functions of inhibiting MGc80-3 cancer cell growth and proliferation.

The invention discloses a traditional Chinese medicine preparation for treating cholelithiasis, comprising the following components in parts by weight: 10-20 parts of bittet orange, 10-20 parts of salvia miltiorrhiza bunge, 10-20 parts of lysima chiachristinae hance, 10-20 parts of radix curcumae, 10-20 parts of radix bupleuri, 10-20 parts of angelica, 10-20 parts of radix paeoniae alba, 10-20 parts of medcinal evodia fruit, 10-20 parts of glauber salt, 10-20 parts of glechoma longituba, 10-20 parts of chicken's gizzard-membrane, 10-20 parts of selfheal, 10-20 parts of scutellaria baicalensis, 10-20 parts of oriental wormwood, 10-20 parts of szechwan chinaberry fruit, 10-20 parts of radix clematidis, 10-20 parts of hawthorn, 10-20 parts of sculellaria barbata, 10-20 parts of spora lygodii, 10-20 parts of rhizoma curcumae longae and 10-20 parts of Tuckahoe. The invention has functions of soothing the liver and benefiting gall bladder, dissolving stasis, activating blood and removing meridian obstruction and resolving and removing calculus. A method for preparing the traditional Chinese medicine preparation is convenient with low production cost.

The invention discloses a traditional Chinese medicine soft capsule for soothing the liver, regulating qi and promoting bile flow, a preparation method of the soft capsule, and a GC (gas chromatography) method for detecting the soft capsule. The pharmaceutical composition disclosed by the invention is prepared from peppermint oil and refined corn oil according to the ratio of 1:(1-3), and a capsule shell is prepared from gelatin, glycerol, water and polyethylene glycol according to the ratio of (0.8-1.2):(0.2-0.6):(0.8-1.2):(0.02-1). The invention also provides a preparation method of the soft capsule and a GC method for measuring the content of menthol in the soft capsule. The clinical test of the traditional Chinese medicine soft capsule disclosed by the invention shows that the total efficiency reaches 98.7%, the capsule shell is nearly not hardened in the storage period, the disintegration time does not exceed 16 minutes, the pill pressing process is reasonable, the production controllability is high, the production cycle is short, and the quality of the used peppermint oil is controllable.

A process for extracting the lognic acid and gentiopicroside from Chinese gentian and their application in preparing medicines for treating liver injury, cholecystitis and bile duct obstruction are disclosed.

The invention relates to a drug for treating chronic cholecystitis, which is a capsule product prepared by the steps of evenly mixing stir-baked rhizoma corydalis with vinegar, stir-baked nutgrass galingale rhizome with vinegar and stir-baked Chinese thorowax root with vinegar after being processed with turmeric root-tuber, costustoot, radix salviae miltiorrhizae, white paeony root, baical skullcap root, Indigowoad root, heartleaf houttuynia herb, green tangerine peel, tangerine peel, honeysuckle flower, weeping forsythiae capsule, officinal magnolia bark, swordlike atractylodes rhizome, common yam rhizome, chicken's gizzard-membrane, bitter orange and liquoric root, adding water for decoction, then concentrating into a thick paste, drying, smashing, packaging in capsules and carrying outsterilization and disinfection. The drug has the effects of soothing the liver, benefiting gallbladder, regulating qi, regulating stomach, clear heating, eliminating dampness, activating blood circulation and relieving pain, is used for treating the chronic cholecystitis and is characterized by actual efficacy, rapidness, convenience and safe administration, and the clinical observation shows thatthe total effective rate is 100%.

The invention discloses a high-fat crucian curing compound feed and a processing technology. Fermented astragalus has high scientific compounding prebiotic property and is capable of obviously improving the body immunity and liver functions; platycodon grandiflorum is capable of effectively reducing the incidence of hyperlipidemia and hyperglycemia symptoms and is effectively improving excessive deposition of fat in liver, spleen and muscle tissues, so that the adaptability of crucian on a high-fat feed is improved, and healthy growth of the crucian is promoted; fish meal is replaced with terrestrial animal protein raw materials, composite grease is compounded scientifically, and by matching different fat raw materials, the crucian growth speed is improved, the feed coefficient is reduced, the body form of the fish is improved, and health of the liver and gall is protected; and a carnitine and cholate degradation inhibitor can achieve the effects of increasing emulsification, digestion and absorption of the fat, promoting biliary secretion and protecting the liver and increasing choleresis and contributes to protecting the health of the liver and gall. Feed tests show that under the conditions that the crude protein content of daily ration is reduced by 2-3% and the crude fat content is increased by 2.1-4.3%, the weight gain rate of the crucian can be increased by 10.99% or more, the feed coefficient is reduced by 12.4% or more, the liver and gall are healthy and normal.

The invention relates to a traditional Chinese medicine composition for treating hypochondriac pain caused by liver and gallbladder damp-heat. The traditional Chinese medicine composition is composed of the following traditional Chinese medicine raw materials in parts by weight: 10-20 parts of angelica, 10-30 parts of radix rehmanniae root of rehmannia, 9-15 parts of cornel, 10-20 parts of fiveleaf akebia fruit, 6-12 parts of chinaberry fruit, 9-15 parts of radix paeoniae alba, 5-15 parts of tuckahoe, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of rhizoma cyperi, 5-15 parts of radix bupleuri, 10-20 parts of jasmine, 9-15 parts of cortex phellodendri, 9-15 parts of radix scutellariae, 10-20 parts of radix curcumae, 10-20 parts of radix clematidis, 9-15 parts of pericarpium citri reticulatae viride, 10-20 parts of zedoary, 5-15 parts of ligusticum wallichii, 20-30 parts of salviae miltiorrhizae, 1-5 parts of rhizoma zingiberis, 10-20 parts of rhizoma corydalis and 3-9 parts of pseudo-ginseng. The traditional Chinese medicine composition provided by the invention has the effects of clearing liver and gallbladder, tonifying spleen and stomach, clearing away heat, drying dampness and warming lung to reduce watery phlegm, and the traditional Chinese medicine composition is significant in curative effect on hypochondriac pain caused by liver and gallbladder damp-heat, reliable in function, wide in component medicine source, simple and convenient to prepare and free of toxic and side effect.

The present invention discloses bear bile-Shuanghuang capsule prepared with bear bile powder, Chinese goldthread and skullcap root in certain weight proportion. The bear bile-Shuanghuang capsule has the pharmacological actions of bacteriostasis, spasmolysis, arresting cough, etc. and functions of clearing away heat and toxic material, benefiting gallbladder, improving eyesight, etc. It may be used widely in treating acute and chronic hepatitis, cholecystitis, gall stone, hypertension, hyperlipemia and other diseases in high curative effect.

The invention relates to a peroral anethol trithione preparation and a preparation method thereof, belonging to the field of pharmaceutical preparations, The preparation method comprises the following steps: dissolving anethol trithione and phospholipid in a compound mode to one or a plurality of fatty acid triglycerides to prepare soft capsules and / or palletizing the phospholipid compound and suitable pharmaceutical excipient to further prepare enteric-coated capsules. Compared with preparations sold in markets, animal experiment results show that the prepared new preparation of the phospholipid compound obviously improves the peroral bioavailability of the anethol trithione and the pharmaceutical concentration in the target tissue liver and predicts favorable liver protection efficacy and cholagogic efficacy.

The invention discloses a lipid-lowering and gallbladder-dredging capsule and belongs to the technical field of traditional Chinese medicine prescriptions. The capsule is prepared from nine types of traditional Chinese medicinal materials, namely radix bupleuri, oriental wormwood, longhairy antenoron herbs, radix et rhizome rhei, rhizoma corydalis, curcuma aromatic, etc. Compatibility of all the medicinal materials is achieved, and the effects of soothing the liver, strengthening the spleen, promoting the circulation of blood and qi, dredging the gallbladder and relieving pain are achieved; the capsule is applicable to costalgia and gallbladeer swelling caused by heat toxin accumulation and lung-qi obstruction, and the symptoms are assistant rib swelling pain, fever, yellow urine and constipation. Through biochemical detection, it is found that triglyceride is raised, and cholesterol is raised. Ultrasonic detection shows that liver light spots are thickened and increased; the capsule is used for treating cholecystitis, gallstones, fatty liver, coronary disease, cerebral thrombosis, hypertension and hyperlipermia. The capsule is clinically applied for more than ten years and well received by patients due to the remarkable treatment effect. The capsule is a pure traditional Chinese medicine capsule preparation obtained through experimental research and development conducted on powder, the capsule is high in content of medicinal compositions, accurate in dosage, reliable in effect and fast in in-vivo disintegration, dispersion, absorption and effect achieving. Production equipment is simple, and the capsule is suitable for mass production to meet the market demand.

The invention discloses a pharmaceutical composition and a preparation method thereof. The pharmaceutical composition comprises quercetin, gallic acid, quercetin-3-0-alpha-L-rhamnopyranoside, pinocembrin-7-0-beta-D-glucopyranose and 2,6-dihydroxyacetophenone-4-0-D-glucopyranose. Compared with the existing drug, the pharmaceutical composition can protect liver and reduce transaminase and relieve the jaundice symptoms, has definite therapeutic effects and has good safety.

The invention discloses a rhizoma curcumae longae and corn peptide tablet and a preparation method thereof. The rhizoma curcumae longae and corn peptide tablet is prepared from the following raw materials in parts by mass: 2-20 parts of rhizoma curcumae longae, 5-30 parts of corn peptide, 20-50 parts of a thickener, 2-20 parts of a sweetening agent, 2-5 parts of pepper, 0.5-3 parts of a preservative and 0.5-3 parts of flow aid auxiliary materials. All the raw materials are mixed uniformly, dry tableting is performed, and coating with a food-grade coating agent, detection and packaging are carried out to obtain the rhizoma curcumae longae and corn peptide tablet. According to the rhizoma curcumae longae and corn peptide tablet prepared with a formula, effective components of the rhizoma curcumae longae are dissolved out quickly and have high bioavailability, and the effects of effective components of the rhizoma curcumae longae can be better played. The rhizoma curcumae longae and cornpeptide tablet has the functions of dispelling alcohol effects, protecting the liver, benefiting choleresis, reducing blood lipid, preventing hypertension, improving organism immunity and the like, and particularly has the best functions of protecting the liver, benefiting choleresis, reducing blood lipid and improving organism immunity.

The invention mainly relates to a preparation process of granules for protecting liver and promoting bile flow. The preparation process comprises the following steps of: 1, distilling raw sytingamicrophylla through water vapor; drying; circularly performing sealing and soaking and ultrasonic-assisted extraction twice; performing alcohol precipitation to the obtained sytingamicrophylla extracting solution at low temperature; carrying out pressure-reduced concentration to obtain a sytingamicrophylla extractive concrete to stand by service for later use; and 2, adding starch and dextrin to the sytingamicrophylla extractive concrete obtained in step 1 based on the weight ratio of (1-1.2): (1.5-2.0): (0.5-1.0); preparing a soft material; granulating; and straightening to accomplish the preparation of the granules. The preparation process provided by the invention is mild; the bioavailability is high; the granules for protecting liver and promoting bile flow, prepared by the process, are high in content of pharmaceutical ingredients, show have remarkable, stable and long-term effect, and have no toxic and side effects.

The invention relates to a Chinese herbal medicine composition for treating calculus. The composition is prepared through compatibility of the following raw materials according to a weight ratio: 0.5-1.5g of bear gall powder, 5-20g of radix curcumae, 10-50g of virgate wormwood herb, 10-30g of Japanese climbing fern spore, 5-15g of shearer's pyrrosia leaf and 3-10g of rhubarb root and rhizome. All the materials are ground into 100-mesh fine powder by utilizing a grinder, and the fine powder is mixed and then filled into capsules to prepare capsules. The Chinese herbal medicine composition has the functions of clearing heat and resolving depression, inducing diuresis and treating stranguria, dispersing stagnated liver qi to promote bile flow and dissolving and removing urinary calculus, is suitable for treating renal calculus, vesical calculus, biliary calculus, calculus of intrahepatic duct and cholecystitis, especially has better curative effects on patients with renal calculus, is safe and efficient, has short courses of treatment, takes an effect quickly and avoids relapse.

The invention provides a total nutrient formula food, a special total nutrient formula food or a non-total-nutrient formula food for cholecystitis and gall-stone patients to eat. According to the requirements of General Rule of Food for Special Medical Purposes, the formula combines the physical characteristics of the cholecystitis and gall-stone patients; the total nutrient formula food is prepared by grinding and mixing various medicinal and edible traditional Chinese medicine extract essences extracted by a prehydrolysis SBE (Starch Branching Enzyme) technology, various microencapsulated probiotics and oligopeptides extracted by biological enzymolysis, prebiotics, amino acid, carbohydrate, various vitamins and mineral substances, and not only can be used as a single nutrient source for meeting the nutrition requirements of the cholecystitis and gall-stone patients, but also takes effects of promoting choleresis, removing urinary calculus, clearing away heat, diminishing inflammation, reducing cholic fire, dispersing stagnated liver qi for promoting bile flow, harmonizing stomach, activating meridians to stop pain, adjusting motion in vital energy, and preventing and treating bile deposition.

The invention discloses a Chinese medicinal composition with mind tranquilizing, antitumour, antibiotic, antiviral, liver protecting, and gallbladder smoothing effects, specially relates to an oral preparation prepared from dahurian patrinia as raw material. The invention is to supply the insufficiency of the present technology in preparing dripping pill, to provide a dripping pill of dahurian patrinia with short dissolvation, high bioavailability, and rapid absorption. The inventive dripping pill of dahurian patrinia is added with chitin in the substrate.

The invention discloses a medicinal preparation used for clearing heat, transforming dampness and soothing liver and gallbladder and used for acute / chronic cholecystitis, biliary tract infection, biliary calculus and the like and a preparation method thereof. The preparation method is characterized in that synthetic bovine bezoar, silymarin, berberine hydrochloride, corydalis root, rhubarb, dandelion, loosestrife and mint oil are used as raw materials, and the raw materials and pharmaceutically acceptable matrix or additive are prepared into dripping pills or soft capsules. The medicinal preparation improves the leaching performance of the medicament, increases the medicament stability, reduces adverse reaction of the medicament, is convenient to carry and take, and is suitable for industrialized production.

The invention discloses traditional Chinese medicinal powder for treating hepatic calculus and a preparation method of the powder. The traditional Chinese medicinal powder is prepared from the following medicinal materials in parts by weight: 31-49 parts of lysimachia christinae hance, 25-40 parts of oriental wormwood, 20-36 parts of typhonium giganteum, 16-30 parts of honeysuckle, 11-26 parts of rhizoma curcumae longae, 9-18 parts of rhizoma cyperi, 3-10 parts of pericarpium citri reticulatae viride, 8-14 parts of rheum officinale, 2-8 parts of amomum cardamomum, 3-7 parts of fructus amomi and 1-6 parts of mangnolia officinalis. The traditional Chinese medicinal powder disclosed by the invention is reasonable in formula, safe and convenient to take, and free from toxic and side effects; and upon clinical verification, the traditional Chinese medicinal powder is concrete and significant in curative effect. On the basis of clinical observation for several years, the medicine has functions of nourishing yin to calm liver, nourishing yin and lowering fire, diminishing inflammation, benefiting bile and removing urinary calculus; and effective rate on treating gallstone and hepatolithiasis caused by liver-yin deficiency and interior dampness-heat reaches more than 90%.

The invention discloses a cholagogic and lithagogue agent for treating a gallstone. The cholagogic and lithagogue agent is prepared from the following raw materials in parts by weight: 13-18 parts of cynanchum paniculatum, 11-16 parts of silybum marianum, 8-15 parts of cattail pollen, 6-9 parts of trogopterus dung, 10-16 parts of semen cuscutae, 12-17 parts of corn stigma, 9-16 parts of immature bitter orange, 11-16 parts of honeysuckle stem, 9-15 parts of amaranthus viridis, 12-18 parts of pericarpium citri reticulatae, 13-20 parts of glechoma longituba and 10-14 parts of szechwan Chinaberry fruit. The cholagogic and lithagogue agent has the excellent effects that the traditional medicine property is organically combined with the modern pharmacology of the traditional Chinese medicine; and by use of the synergistic effects of the medicinal materials, the cholagogic and lithagogue agent plays roles in clearing away heat and toxic materials, protecting the liver, benefiting the gallbladder, resisting inflammation and dissolving the stone, and has a significant curative effect on the gallstone. The cholagogic and lithagogue agent is capable of obviously improving the clinical symptoms of patients and relieving the pain, and has the efficacies of being short in treatment course, fast in action effect, and free of relapse of healed gallstone.

The invention relates to a traditional Chinese medicine composition for treating gall stones and a preparation method thereof. The traditional Chinese medicine composition is a medicament being prepared from christina loosestrife, radix scutellariae, coptidis rhizoma, rhubarb, radix aucklandiae, fructus aurantii, curcuma, melia toosendan, polygonum cuspidatum, endothelium corneum gigeriae galli, gardenia, rhizoma phragmitis and the like. The medicament is unique in formula, is definite in curative effects, is safe and economical, is free of significant toxic and side effects, has effects of dispersing liver and soothing depression, moving qi to relieve pain, draining gallbladder and discharging stone, and fortifying spleen and draining dampness, and is suitable for patients suffered from gall stones and cholecystitis.

The invention discloses medicine for treating cholecystitis and a preparation method thereof. The medicine is prepared by 45-55 parts of loofah sponge and 45-55 parts of dandelion. The preparation method includes: soaking the medicinal materials into 450-550 parts of Baijiu for 13-18 days to obtain the medicine. The medicine has the effects of soothing the liver and gallbladder, regulating qi flow and removing dampness, activating blood and diminishing inflammation and eliminating evil and relieving pain, and is good in curative effect on the cholecystitis, safe and free of toxic and side effects, and evident in curative effect.

The invention discloses a traditional Chinese medicine composition for treating cholecystitis and cholelithiasis. The traditional Chinese medicine composition comprises fructus aurantii, flos Lonicerae, radix bupleuri, fructus forsythiae, fructus arctii, radix aucklandiae, radix glycyrrhizae, and Tetrapanax papyriferus. The invention also discloses a preparation method of the traditional Chinese medicine composition. The formula of the invention has reasonable compatibility, can effectively improve the synergistic effect between the drugs, has effects of soothing liver and gallbladder, clearing heat and diuresis, promoting qi circulation and analgesia, increasing choleresis and removing urinary calculus, has no obvious liver and kidney toxicity, can be widely applied to the treatment of cholecystitis and cholelithiasis, and has the advantage of treating both symptoms and root causes.

The invention discloses a traditional Chinese medicine for treating nephritis. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 50g of Hypericum monogynum L. fruits, 15g of spora lygodii, 15g of Polygonum aviculare L. herba, 30g of herba plantaginis, 15g of folium pyrrosiae, 10g of rhizoma alismatis, 10g of rhizoma acori tatarinowii, 20g of Rosa roxburghii Tratt. roots, 10g of coicis semen, 15g of herba taraxaci, 15g of herba houttuyniae, 10g of cortex eucommiae, 15g of radix dipsaci, 30g of Chrysopogon aciculatus (Retz.) Trin. herba, 30g of herba lysimachiae, 20g of Oxalis corniculata L. herba, 15g of Maclura cochinchinensis (Loureiro) Corner roots and 15g of herba artemisiae scopariae. The traditional Chinese medicine disclosed by the invention has the efficacy of tonifying spleen, supplementing stomach, promoting blood circulation to remove blood stasis, inducing diuresis, reducing edema, dispersing stagnated liver qi for promoting bile flow, dredging collaterals and removing stones, and can effectively treat the nephritis, nephrotic syndromes and various stones of kidney, gallbladder and the like.

The invention relates to a medicine for treatment of cholecystitis. A pharmacodynamic test proves that the compound has significant choleretic effect and after drug delivery, can significant bile secretion quantity. The medicine has long lasting time and is better in effect of promoting excretion effect of bilirubin in the bile, so that the compound is suitable for treatment of the cholecystitis.

The invention provides a total nutrient formula food, a specific total nutrient formula food or a non-total nutrient formula food for people with damp and hot habitus to eat. The formula is researched by combining the features of people with damp and hot habitus and integrating research achievements of the advanced physiology, medicine, nutriology, clinical application and the like of the Harvard University at present according to the requirement on The general principles of the special medical use formula in accordance with the essence theory (homology of the liver, the spleen, the kidneys acts as the main principle) of traditional Chinese medicine such as'combination of elimination and nourishment' and'equilibrium maintenance'. The food is prepared by mixing the main raw materials such as multiple traditional Chinese medicine extract essence, multiple probiotics and oligopeptide with the medical-edible purpose and auxiliary materials such as probiotics, carbohydrate, amino acid, multiple vitamins and minerals, not only can act as a single nutrient to meet the nutritional requirements on people with damp and hot habitus, but also can play roles of soothing liver-gallbladder, dispelling dampness and heat, clearing away the lung-heat, clearing away heat and toxic materials, tonifying spleen, excreting dampness and strengthening the immunity.

The invention belongs to the technical field of biological medicines and particularly relates to novel application of Apiosylskimmin in preparation of a medicine for treating cholestasis. Firstly, the invention discovers that the Apiosylskimmin can be used for exciting FXR and CAR in a targeted manner and can be used for preparing FXR and CAR agonists; secondly, it is found that the Apiosylskimmin can be used for remarkably inhibiting the content of total bilirubin (TBIL) and total bile acid (TBA) of cholestasis model mice and inhibiting the activity of alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP) and glutamyl transferase (GGT), the Apiosylskimmin has the remarkable double effects of benefiting gallbladder and removing jaundice, and the effect of the Apiosylskimmin is equivalent to or better than that of existing clinical medicine obeticholic acid; and in addition, the Apiosylskimmin is basically non-toxic and good in safety, and can be used for preparing the medicine for treating the cholestasis and related complications thereof.

The invention relates to a traditional Chinese medicine preparation for treating gallstone. The preparation is prepared from the following components in parts by weight: 15-25 parts of lysimachia christinae hance, 15-25 parts of fish otolith, 10-15 parts of endothelium corneum gigeriae galli, 10-20 parts of curcuma sichuaensis, 10-20 parts of lygodium japonicum, 8-15 parts of pericarpium citri reticulatae viride, 8-15 parts of artemisia capillaris, 8-12 parts of polygonum cuspidatum, 5-10 parts of hance brandisia herb, 5-10 parts of codonopsis pilosula, 5-10 parts of rheum officinale and 5-10 parts of pyrrosia lingua. The traditional Chinese medicine has a unique curative effect for intractable gallstone, and is prepared from multiple traditional Chinese medicinal herbs which are synergetic and are used for treating diseases comprehensively, so that effective ingredients of the medicinal materials can be quickly infiltrated to the focus, blood circulation of a diseased region is improved, and the effects of eliminating stone, promoting bile flow and dispersing stagnated liver qi can be achieved.