Photoacoustic endoscope

An endoscope and laser technology, used in catheters, operations, etc., can solve the problems of low imaging resolution, low soft tissue contrast, and can not fully meet clinical needs, and achieve the effect of high image resolution and good optical resolution.

Active Publication Date: 2013-12-25
SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The optical endoscope can only image the surface of the internal biological tissue through the CCD, and cannot observe the tissue below the epidermis, which limits its ability to diagnose diseases to a certain extent
New optical endoscopes, such as OCT endoscopes, can image the section of the digestive tract or coronary arteries through focused beams, and have high resolution, but because they can only be used without tissue scattering or only through a few Subscattered ballistic photon imaging has an imaging depth of only about 1 mm, which cannot fully meet clinica

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0040] Example 1

[0041] Such as image 3 with Figure 4 As shown, the optical fiber 212 is provided in the fiber optic conduit 214. Further, in this embodiment, the optical fiber conduit 214 is provided with a flexible conduit 216. The optical fiber is wrapped in a flexible tube 216.

[0042] The endoscopic probe 220 includes an optical component and a fixing component (not marked in the figure). Among them, the optical assembly includes a self-focusing lens 221 and a reflector 222. The fixing assembly includes a rigid pipe 224 with a photoacoustic window 223 at the free end and a plastic sleeve 225 arranged inside the rigid pipe 224.

[0043] The fiber optic conduit 214 is partially inserted into the rigid conduit 224. The outer wall of the optical fiber catheter 214 inserted into the rigid catheter 224 is sleeved with the inner wall of the rigid catheter 224. The ends of the flexible conduit 216 and the optical fiber 212 are flush, and pass through the optical fiber conduit ...

Example Embodiment

[0047] Example 2

[0048] Such as Figure 5 As shown, the structure of the endoscopic probe and optical fiber of this embodiment is similar to that of Embodiment 1. The difference is that the right-angle prism 422 in this embodiment is different from the reflector 222 of the isosceles right-angle prism used in Embodiment 1. Therefore, in this embodiment, the adjustment member 228 is not provided to ensure that the ultrasonic transducer 426 can receive the excited ultrasonic signal of the target tissue vertically.

Example Embodiment

[0049] Example 3

[0050] Such as Image 6 As shown, the optical fiber 512 is provided in the optical fiber conduit 514. Furthermore, in this embodiment, a flexible conduit 516 is provided in the optical fiber conduit 514. The optical fiber is wrapped in a flexible tube 516.

[0051] The endoscopic probe 520 includes an optical component and a fixing component (not marked in the figure). Among them, the optical assembly includes a self-focusing lens 521 and a reflector 522. The fixing assembly includes a rigid pipe 524 with a photoacoustic window 523 at the free end and a plastic sleeve 525 arranged inside the rigid pipe 524.

[0052] The ends of the flexible conduit 516 and the optical fiber 512 are flush, and pass through the optical fiber conduit 514, partially inserted into the plastic sleeve 525, and are coaxially connected with the self-focusing lens 521 at the end. The self-focusing lens 521 is wrapped in a plastic sleeve 525 and is coaxially connected to the flexible tube...

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Abstract

The invention relates to a photoacoustic endoscope comprising a control system, a laser source, an optical path system, an endoscope probe, a probe scanning system, a data acquisition system, an image reconstruction system and a display system, wherein the photoacoustic endoscope tightly focuses lasers into a target tissue, detects ultrasonic signals generated after the lasers are absorbed by the target tissue, carries out the analysis process and images; the optical absorption characteristic of a biomass tissue is closely related with the change of physiological functions, so that the photoacoustic endoscope can more accurately react the image characteristic of the target tissue, has higher image resolution, contrast ratio and sensitivity, can effectively improve the resolution of the traditional photoacoustic endoscopic imaging by 10-100 times, and has better optical resolution effect.

Description

technical field [0001] The invention relates to the field of biomedical devices, in particular to a photoacoustic endoscope. Background technique [0002] Endoscopic imaging, as a non-invasive imaging method, is widely used in many fields of biomedicine and clinical diagnosis. Endoscopes effectively extend the human line of sight and can accurately observe the surface and / or internal features of biological tissues. [0003] Traditionally commonly used endoscopes mainly include optical and ultrasonic. The optical endoscope can only image the surface of the internal biological tissue through the CCD, and cannot observe the tissue conditions below the epidermis, which limits its ability to diagnose diseases to a certain extent. New optical endoscopes, such as OCT endoscopes, can image the section of the digestive tract or coronary arteries through focused beams, and have high resolution, but because they can only be used without tissue scattering or only through a few Subscat...

Claims

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Application Information

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IPC IPC(8): A61B8/12
Inventor 宋亮白晓淞
Owner SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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