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A kind of intestinal mucosa protection and repair type enteral nutrition product and preparation method thereof

A technology of nutrition and products, which is applied in the field of functional nutrition for intestinal mucosal protection and repair and its preparation, can solve the problems that the efficacy and nutrition cannot be taken into account at the same time, the function of chemical drugs is single, and the ingredients of traditional Chinese medicine are complex, so as to enhance and promote Intestinal mucosal repair effect, reduce endotoxin translocation, and promote intestinal peristalsis

Active Publication Date: 2016-09-07
SOUTH CHINA SEA INST OF OCEANOLOGY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The chemical drugs or traditional Chinese medicine prescriptions used in the above measures all have certain deficiencies: the functions of chemical drugs are relatively single, and the efficacy and nutrition cannot be taken into account at the same time.
For patients who have experienced major trauma, major surgical operations, and tumor patients undergoing radiotherapy and chemotherapy, the patent aims at strengthening and repairing the intestinal mucosa, and its components and functions are relatively simple
The composition of traditional Chinese medicine preparations is complex, the treatment process is longer, and the onset of effect is slower

Method used

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  • A kind of intestinal mucosa protection and repair type enteral nutrition product and preparation method thereof
  • A kind of intestinal mucosa protection and repair type enteral nutrition product and preparation method thereof
  • A kind of intestinal mucosa protection and repair type enteral nutrition product and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0072] Raw materials that meet the relevant national edible standards are fresh oysters cultured in sea water. The materials are obtained by washing, shelling and viscera removal, adding 1:3 pure water according to the weight to volume ratio, and mixing until homogeneous. According to the weight of the material, add 1% trypsin, adjust the pH, keep the temperature at 40°C, and perform enzymatic hydrolysis for 7 hours. Centrifuge to remove the precipitate, and the supernatant is passed through an ultrafiltration membrane to obtain a peptide solution below 5000 Da, and then concentrated in a vacuum to obtain a small molecule peptide solution separated by enzymatic hydrolysis of oysters.

[0073] Take 2.0 parts of marine animal enzymatic hydrolysis and separation of small molecule peptide liquid (dry weight basis), 15.0 parts of soybean peptide, 4.0 parts of medium and long-chain fatty acid edible oil, 76 parts of maltodextrin, 2.0 parts of polydextrose, 0.5 part of stachyose, Ala ...

Embodiment 2

[0077] Raw materials that meet the relevant national edible standards are fresh octopus cultured in sea water, cleaned and removed from the viscera to obtain materials, added 1:3 purified water according to the weight-to-volume ratio, and crushed to homogenize. According to the weight of the material, add 3% pepsin, adjust the pH, keep the temperature at 40°C, and perform enzymatic hydrolysis for 6 hours. Centrifuge to remove the precipitate, and the supernatant is passed through an ultrafiltration membrane to obtain a peptide solution below 5000 Da, and then concentrated in a vacuum to obtain a small molecule peptide solution separated by enzymatic hydrolysis of octopus.

[0078] Take 10.0 parts of octopus enzymatic hydrolysis and separation of small molecule peptide liquid (dry weight basis), 15.0 parts of soybean peptide, 10.0 parts of medium and long-chain fatty acid edible oil, 43 parts of maltodextrin, 10.0 parts of soybean dietary fiber, 3.0 parts of raffinose, Arg- 9.0...

Embodiment 3

[0082] Raw materials that meet the relevant national edible standards are fresh cobia cultured in sea water, cleaned, scaled and viscerated to obtain materials, and purified water of 1:3 is added according to the weight-to-volume ratio, and crushed and homogenized. According to the weight of the material, add 2% papain, adjust the pH, keep the temperature at 50°C, and perform enzymatic hydrolysis for 8 hours. Centrifuge to remove the precipitate, and the supernatant is passed through an ultrafiltration membrane to obtain a peptide solution below 5000 Da, and then concentrated in a vacuum to obtain a cobia enzymatic hydrolysis and separation of small molecules.

[0083] Take cobia enzymatic hydrolysis and separation of small molecule peptide liquid 10.0 parts (dry weight basis), soybean peptide 5.0 parts, medium and long-chain fatty acid edible oil 4.0 parts, maltodextrin 78.0 parts, soybean dietary fiber 2.0 parts, fructooligosaccharides 0.5 parts, Gly -0.5 part of Gln, and fa...

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Abstract

The invention belongs to the field of nutritious food production, and specifically relates to a functional nutrient product for intestinal mucosa protection and repair and a preparation process thereof. It provides a kind of food that can protect intestinal mucosa and promote its repair after damage, prevent and relieve constipation of patients, and Products that provide balanced nutritional support, composed of marine animal small molecule peptides, glutamine dipeptides, soybean peptides, maltodextrin, dietary fiber, medium and long-chain fatty acid edible oils, etc., supplemented by multivitamins, prebiotics and probiotics , formulated according to the nitrogen and calorie requirements recommended by moderately stressed patients, it can protect and promote the repair of intestinal mucosa, promote the intestinal colonization of beneficial bacteria to inhibit the proliferation of harmful bacteria, reduce the production of endotoxin and prevent its displacement, and provide a pathological period Nitrogen sources, carbohydrates, fats, and vitamins required by the human body. It is suitable for patients with intestinal mucosal injury caused by various factors such as trauma, major surgery, and tumor chemotherapy. It is safe and has no toxic and side effects. It can be made into powder and functional nutritional suspension.

Description

technical field [0001] The invention belongs to the field of nutritional food production, and in particular relates to a functional nutritional product for intestinal mucosa protection and repair and a preparation process thereof. Background technique [0002] The audience of this nutritional product is patients with major trauma, patients who need nutritional enhancement before surgery and nutritional support after surgery, and cancer patients during radiotherapy and chemotherapy. [0003] After the human body suffers major trauma, shock, and major surgical operations, the body is in a state of stress, and the body functions will preferentially distribute blood to important organs such as the heart and brain. recover. Intestinal blood flow hypoperfusion or hypoxia slows down normal intestinal peristalsis, causes bacterial flora imbalance, causes pathogenic bacteria to proliferate, releases bacterial proteases and lipopolysaccharide (LPS)-based endotoxins, and directly dama...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23L33/00
CPCA23L33/40A23V2002/00A23V2400/123A23V2400/533A23V2200/32A23V2250/55A23V2250/5114A23V2250/5042A23V2250/632A23V2250/70A23V2250/5116A23V2250/622A23V2250/28
Inventor 潘剑宇孙恢礼陈华蔡冰娜
Owner SOUTH CHINA SEA INST OF OCEANOLOGY - CHINESE ACAD OF SCI
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