Polyether-ether-ketone biomimetic artificial bone 3D printing manufacturing method

Abstract

The invention discloses a polyether-ether-ketone biomimetic artificial bone 3D printing manufacturing method, wherein the artificial bone can replace metal and has an excellent biocompatibility. The method comprises the following steps: first, collecting the bone tissue image data of the part, which is about to be implanted with an artificial bone, of a patient by using a medical instrument; secondly, establishing a three-dimensional digital model of the artificial bone on the basis of the collected data; thirdly, carrying out a format conversion on the three-dimensional digital model of artificial bone, inputting the converted file into a 3D printing system to manufacture the artificial bone; and finally carrying out cell toxicity tests, animal tests, and clinical tests. The invention utilizes a self-made polyether-ether-ketone 3D printing system to manufacture artificial bones, thus the time and cost for manufacturing moulds are saved, the manufacture period is shortened; at the same time, the shape of parts can be adjusted at any time according to the setting of the forming software; so that an crystalline polymer polyether-ether-ketone artificial bone, which has excellent biocompatibility, can be implanted into the human body, and has the advantages of high melting point, large viscosity, and bad fluidity, can be manufactured through the 3D printing method.

Description

technical field [0001] The invention belongs to the technical field of 3D printing, and in particular relates to a 3D printing manufacturing method of polyetheretherketone bionic artificial bone. Background technique [0002] Polyether ether ketone is a new type of engineering plastic developed by the British ICI company in 1977. It has the high temperature resistance of thermosetting plastics, excellent mechanical strength (high strength, high elastic modulus, high fracture toughness), Chemical stability, radiation resistance and electrical properties, combined with the ease of processing of thermoplastic materials. In the field of biomedicine, polyether ether ketone has excellent biocompatibility. Compared with metal material implants, its elastic modulus is closer to the elastic modulus of human bone, which greatly reduces the elastic modulus due to metal materials and human bone. If the gap is too large, problems such as stress shielding, bone resorption, bone inflammat...

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Problems solved by technology

[0005] The purpose of the present invention is to provide a 3D printing manufacturing method of polyether ether ketone bionic artificial bone, aiming to solve the problem that the current polyether ether ketone material is basically formed by traditional processing techniques such as injection molding and molding, and its manufacturing cost is high, the shape of the part is single, Problems such as long production cycle and inability to carry out 3D printing and manufacturing of polyetheretherketone

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