A kind of bisphenol antioxidant and preparation method thereof
An antioxidant and bisphenol technology, applied in the field of bisphenol antioxidant and its preparation, can solve the problems of low molecular weight, high price, no improvement in melting point and extraction resistance, etc., and achieve good antioxidant effect, low cost effect
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[0025] A kind of synthetic method of bisphenol antioxidant, comprises steps:
[0026] 1) Under the catalysis of a catalyst, p-cresol and alkyl acid chloride are acylated to obtain 2-alkylacyl p-cresol;
[0027] 2) Reducing 2-alkylacyl-p-cresol to obtain 2-alkyl-p-cresol;
[0028] 3) Then 2-alkyl acyl p-cresol is prepared by methylation reaction.
[0029] Its synthetic route is shown as follows:
[0030]
[0031] The catalyst is a protonic acid, which cannot ionize H + Lewis acid, strong acid ion exchange resin; preferably, the catalyst is boron trifluoride, aluminum chloride, zinc chloride, benzenesulfonic acid, p-toluenesulfonic acid, concentrated sulfuric acid, strong acid ion exchange resin One; more preferably, the catalyst is one of aluminum chloride, zinc chloride, and strong acid ion exchange resins.
[0032] The structural formula of described 2-alkyl p-cresol is as follows:
[0033] ;
[0034] In the structural formula of 2-alkyl p-cresol, n is 5-20; prefer...
Embodiment 1
[0036] Embodiment 1: the synthesis of intermediate 2-heptanoyl p-cresol
[0037] Quickly weigh 40g catalyst anhydrous AlCl 3 In the round bottom flask, install the tail gas absorbing device, add 32.4g of p-cresol and 44g of heptanoyl chloride dropwise respectively with a constant pressure dropping funnel, after the dropwise addition, raise the temperature to 100°C for 2 hours under stirring, and then cool down to room temperature Dissolve the reactant with 2mol / L hydrochloric acid, separate the organic layer, extract the aqueous layer with 200ml*3 chloroform, wash the combined organic layer with 300ml water and saturated saline, dry over anhydrous magnesium sulfate, filter with suction The solvent was evaporated under pressure to obtain the target product, 63 g (0.29 mol, 97%) of a light yellow liquid. EIMS (70eV) m / z :220(M+).
Embodiment 2
[0038] Embodiment 2: the synthesis of intermediate 2-octanoyl p-cresol
[0039] Quickly weigh 44g of anhydrous AlCl 3 In the round-bottomed flask, install the tail gas absorption device, add 35.6g of p-cresol and 54g of nonanoyl chloride dropwise with a constant pressure dropping funnel, and after the dropwise addition, raise the temperature to 100°C for 3 hours under stirring, and the subsequent treatment is the same as the implementation Example 1, 73 g (0.31 mol, 93%) of light yellow liquid was obtained. EIMS (70eV) m / z :234(M+).
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