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Manyprickle Acathopanax Root extrat, and preparation method and application thereof

An acanthopanax senticosus extract and extract technology are applied in the directions of drug combination, plant raw materials, medical preparations containing active ingredients, etc., which can solve the problems of low polysaccharide content and many impurities, and achieve simple process, less environmental pollution, The effect of easy quality control

Active Publication Date: 2014-06-18
LUOYANG HUIZHONG ANIMAL MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The traditional water extraction and alcohol precipitation method to prepare Acanthopanax polysaccharides, although the operation process is simple, but there are many impurities in the product and the content of polysaccharides is low

Method used

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  • Manyprickle Acathopanax Root extrat, and preparation method and application thereof
  • Manyprickle Acathopanax Root extrat, and preparation method and application thereof
  • Manyprickle Acathopanax Root extrat, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Extraction of flavonoids and polysaccharides from different parts of Acanthopanax senticosus: Weigh respectively 100 g of Acanthopanax senticosus leaves, roots / bark, and stem / bark treated according to the method in Example 2, and extract respectively according to the method in Example 3. The specific results are shown in the table below .

[0032] Sample site

[0033] stem bark

Embodiment 2

[0035] Acanthopanax stem bark pre-treatment: weigh the bark of Acanthopanax senticosus, crush it, pass through a 5-10 mesh sieve, put it in an ultrasonic cleaner or an extractor, and extract it with petroleum ether (30-60°C) to It is colorless, the petroleum ether is poured off, the medicinal material is taken out and dried, and the treated Acanthopanax senticosus sample is obtained. Dried at 60° C. for 3 hours to obtain the treated Acanthopanax (namely Acanthopanax coarse acnes) for future use.

Embodiment 3

[0037] Extraction and preparation of the active ingredient total polysaccharides of Acanthopanax senticosus: Get 200 g of the coarse Acanthopanax five-five-skin medicinal material (5-10 mesh) prepared in Example 2, and 4% (accounting for total material dry weight) auxiliary agent (Na 2 CO 3 / Na 2 B 4 o 7 , 1:1, W / W) mixed into the extraction tank, added 50 times 10000mL of 15wt% ethanol aqueous solution, stirred at 50-60°C for 1.5h, and filtered with suction to obtain the extract, and the dregs were extracted twice, combined The extract is adjusted to a pH of 4.0 with dilute hydrochloric acid, left to stand, centrifuged and precipitated to obtain flavonoids, one of the active ingredients of Acanthopanax. Concentrate the supernatant obtained by centrifugation to 1.0g crude drug / mL, add 3 times the amount of 95wt% ethanol to precipitate, let it stand overnight at 4°C, and centrifuge at high speed and low temperature (8000 rpm, 30min, 4°C) to obtain a precipitate , after vacu...

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Abstract

The invention relates to a Manyprickle Acathopanax Root extract. The polysaccharide content of the Manyprickle Acathopanax Root extract is 50-80wt%. The invention also provides a method for extracting effective components from Manyprickle Acathopanax Root, a Manyprickle Acathopanax Root polysaccharide having a good immunological enhancing effect and screened from the effective components, and a preparation method of a Manyprickle Acathopanax Root polysaccharide granule. The Manyprickle Acathopanax Root disclosed in the invention can be used to prevent and treat infectious bursal disease viruses of animals and infectious bronchitis viruses and improve the growth performance of the animals. The Manyprickle Acathopanax Root extract has a protruding immune effect in the pharmacological evaluate field, can be used to prepare medicines widely used in veterinary clinically, and has a broad market prospect and a high value.

Description

technical field [0001] The invention belongs to the technical field of extraction and application of traditional Chinese medicines, and in particular relates to the extraction of effective component polysaccharides from Acanthopanax acanthopanax and its application in the field of related medicines. Background technique [0002] In view of the urgent need to solve the problems of drug residues, drug resistance and toxic side effects in meat, eggs and dairy products caused by the abuse of antibiotics, chemical drugs and hormone drugs at home and abroad, in the current modern livestock and poultry farming, worldwide There has been an upsurge of returning to nature. People respect nature and attach importance to ecological safety and food safety. A consumption trend has formed at home and abroad that requires "high quality, low drug residues, green and pollution-free" for edible products. [0003] The immune enhancer of traditional Chinese medicine is a very important class of ...

Claims

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Application Information

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IPC IPC(8): A61K36/254A61P15/08A61P31/14A61P37/04A61P43/00
Inventor 张许科刘兴金张晓会
Owner LUOYANG HUIZHONG ANIMAL MEDICINE
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