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Organosilicon quaternary ammonium salt antibacterial agent for synergism of skin and application of antibacterial agent

A technology of organosilicon quaternary ammonium salt and antibacterial agent, applied in the directions of skin care preparations, topical antibacterial agents, skin diseases, etc., can solve the problems of high cost, increased cost, high equipment requirements, etc., and achieves low cost and strong stability. , the effect of improving the antibacterial effect

Inactive Publication Date: 2014-07-30
NANXIONG DING CHENG NEW MATERIAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Such as U.S. Patent US6613755, it is proposed to use ultra-pure water as the medium, and the purity resistivity of water is required to reach more than 18 megohm centimeters, so that a stable silane quaternary ammonium salt solution can be obtained, and various stable disinfectant hand sanitizers and facial cleansers can be made. etc., but the preparation of ultrapure water requires high equipment, and it is difficult for domestically produced pure water for the electronics industry to reach a resistivity of 18 megohm cm, and ultrapure water has high requirements for packaging containers and the surrounding environment, which is difficult practical
US6087319 adopts adding a large amount of propylene glycol ethers, alkyl quaternary ammonium salts and acrylic surfactants in water to obtain a stable aqueous solution, but the cost is relatively increased, and there is no guarantee for antibacterial effect and washability
Another example is that US662172 adopts propylene carbonate and ethylene glycol butyl ether as a solvent, and then adds water to obtain a stable aqueous solution, but how long it can be stored is not specified, and propylene carbonate and ethylene glycol butyl ether are used in a large amount, and the cost is high

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0015] Below in conjunction with embodiment the present invention is further described.

[0016] A synergistic organosilicon quaternary ammonium salt antibacterial agent for skin, its components include organosilicon quaternary ammonium salt, and cooperate with citric acid, acetic acid, boric acid synergist, and use deionized water as a dispersion medium to prepare organosilicon Aqueous solution of quaternary ammonium antibacterial agent.

[0017] The organosilicon quaternary ammonium salt includes 3-(trimethoxysilyl)propyl octadecyl dimethyl ammonium chloride, 3-(triethoxysilyl)propyl octadecane, dimethyl chloride ammonium chloride, 3-(trimethoxysilyl)propyloctadecyldimethylammonium chloride and 3-(triethoxysilyl)propyloctadecyldimethylammonium chloride ammonium chloride, the solvent used when the organosilicon quaternary ammonium salt is synthesized can use isopropanol, ethylene glycol methyl ether, propylene glycol methyl ether, ethylene glycol butyl ether, ethanol, methan...

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PUM

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Abstract

The invention relates to an organosilicon quaternary ammonium salt antibacterial agent for synergism of skin, and the organosilicon quaternary ammonium salt antibacterial agent comprises organosilicon quaternary ammonium salt. The organosilicon quaternary ammonium salt is matched with citric acid, acetic acid and boric acid synergists and deionized water is used as a dispersion medium so that organosilicon quaternary ammonium salt antibacterial agent water solution is prepared. The organosilicon quaternary ammonium salt antibacterial agent for synergism of skin has the characteristics of strong stability and low cost, and has safety to human body and tenderness to skin at the same time.

Description

technical field [0001] The invention relates to a synergistic organosilicon quaternary ammonium salt antibacterial agent specially used for skin and application thereof. Background technique [0002] Organosilicon quaternary ammonium salt, 3-(trialkoxysilyl)-propyl octadecyl dimethyl ammonium chloride, is a durable and washable fabric finishing agent invented by Dow Corning in the 1970s. . Because it has a quaternary ammonium salt cationic gene, it has a broad-spectrum antibacterial and bactericidal effect on various bacteria such as Gram-positive bacteria, Gram-negative bacteria and fungi, and because its molecule contains three methoxyl Group (or ethoxy group), easily hydrolyzed into three silanol groups in water, and easily polycondensed into water-insoluble network polysiloxane. Therefore, it cannot be stored in water as a solvent, but can only be stored in alcohol solvents or other non-aqueous solvents. [0003] Companies and individuals who have been engaged in rese...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/22A61K8/86A61K8/58A61K8/362A61K8/19A61P31/04A61P31/02A61P17/04A61P17/00A61Q19/10A61Q5/02A61K31/194A61K31/695
Inventor 周涛周宇鹏
Owner NANXIONG DING CHENG NEW MATERIAL TECH CO LTD