Expanding continuous-flow balloon catheter and preparation method thereof

A balloon and flow ball technology, which is applied in the direction of balloon catheter, dilator, surgery, etc., can solve the problems of pressure difference safety, affect the performance of the balloon, and be difficult to achieve, so as to achieve good pressure resistance and anti-corrosion. Improved extrusion performance and low production cost

Active Publication Date: 2014-07-30
LIAONING YINYI BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the balloon is perforated on the balloon body to form a hollow channel. On the one hand, it will affect the performance of the balloon, and there are problems in the safety of the pressure difference. On the other hand, the technical level is relatively high, and it is generally difficult to achieve.

Method used

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  • Expanding continuous-flow balloon catheter and preparation method thereof
  • Expanding continuous-flow balloon catheter and preparation method thereof
  • Expanding continuous-flow balloon catheter and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] use as figure 1 , 2 The shape of the balloon shown in the mold is formed by pressurized heating and blow molding with a hollow tube, the forming pressure is 28bar, and the forming temperature is 50°C. The balloon 3 with two lobes on the edge is made. After the balloon 3 is filled, it is formed A hollow passage 2 . The cross-section of the hollow channel is round hole, oval hole or other irregular polygons. The balloon 3 is welded together with the outer catheter 4 and the inner catheter 1 equipped with the developing ring 5, and the inner catheter is arranged on one side of the balloon; the outer surface of the outer catheter is coated with a lubricating coating, and the surface of the balloon is coated with drugs . The hollow pipe used in this embodiment is a polyamide (nylon 12) pipe. The lubricious coating on the outer catheter is polyvinylpyrrolidone. The drug coated on the outer surface of the balloon is paclitaxel.

Embodiment 2

[0027] In this embodiment, as figure 1 , 2 The mold of the shape of the balloon shown is formed by pressurized heating blow molding with a hollow tube, the forming pressure is 38bar, and the forming temperature is 140°C. The hollow tube used is block polyetheramide. The lubricious coating on the outer catheter is polyethylene glycol. The drug coated on the outer surface of the balloon is rapamycin and its derivatives, and the rest are the same as in Example 1.

Embodiment 3

[0029] In this embodiment, as figure 1 , 2 The shape of the balloon shown in the mold is formed, and the hollow tube is pressurized and heated by blow molding. The forming pressure is 16bar, and the forming temperature is 200°C. The outer surface of the outer catheter is coated with a lubricating coating, and the surface of the balloon is coated with drugs. . The hollow pipe is polyethylene terephthalate (PET). The lubricating coating is polypropylene glycol. The drug coated on the outer surface of the balloon is resveratrol. All the other are with embodiment 1.

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Abstract

The invention relates to an expanding continuous-flow balloon catheter. The expanding continuous-flow balloon catheter comprises an inner catheter, an outer catheter, a balloon and a developing ring, wherein the balloon is connected with the outer catheter and the inner catheter which is provided with the developing ring; the edge of the balloon comprises two flaps or three flaps; after the balloon is filled, one or three hollow channels are formed. The expanding continuous-flow balloon catheter has dredging and expanding functions and a medicament bracket function of a general common balloon catheter; the edge of the balloon comprises two flaps or three flaps, and after the balloon is filled, one or three hollow channels are formed, so that the section of a blood vessel cannot be completely blocked by the expanded balloon, and the blood in the blood vessel is still in a circulation maintaining state. Particularly, when the edge of the balloon comprises three flaps, the three hollow channels are uniformly distributed, and the anti-extrusion performance is high, so that the blood is distributed more uniformly. According to the expanding continuous-flow balloon catheter, the passage outside diameter is small, and the material is soft, so that the expanding continuous-flow balloon catheter is easy to pass a diseased region. The expanding continuous-flow balloon catheter is simple in technical process, and low in production cost.

Description

technical field [0001] The invention relates to an interventional medical device, in particular to an inflatable non-stop flow balloon catheter and a preparation method thereof. Background technique [0002] Since the epoch-making Percutaneous Transluminal Coronary Angioplasty (PTCA) was launched in 1977, cardiac interventional technology has experienced more than 30 years of development and has become one of the important means of coronary heart disease treatment. In the initial stage, the use of PTCA balloons for coronary vasodilator surgery can unblock narrowed or blocked coronary arteries, which is one of the effective methods for clinical treatment of coronary heart disease. However, severe complications such as vascular intimal tear and even acute occlusion are easy to occur during the operation, and the restenosis rate after operation is high due to the elastic retraction and chronic contraction of blood vessels. The stenosis rate was nearly 33%. Therefore, PTCA bal...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M25/10A61M29/02
Inventor 董何彦卢春兰马德鑫杜旭东杨刚
Owner LIAONING YINYI BIOTECH CO LTD
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