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Preparation method of weikang capsule

A technology of Weikang capsules and process steps, which is applied in the field of preparation of Weikang capsules, can solve the problems of longer production cycle, longer time for active ingredient absorption, higher production costs, etc., to achieve easy crushing, avoid heat softening and stickiness, Effect of reducing volatile loss

Inactive Publication Date: 2014-08-06
沈阳神龙药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Although the traditional pharmaceutical process can extract most of the active ingredients of raw medicinal materials, there are also certain disadvantages: frankincense and myrrh are resinous traditional Chinese medicines, and the main components are resin, gum and volatile oil. The heat generated by the traditional crushing method is easy to use. Frankincense and myrrh soften and become sticky and difficult to form powder, which also makes the equipment difficult to clean. If the temperature is too high, the active ingredients will be lost more easily; the prescription consists of Baiji, sea octopus, gallinaceous gold, egg shell (fried) and fine powder of Baicao cream When used as medicine, the active ingredients take a long time to absorb, which is not conducive to exerting the drug effect; because Panax notoginseng contains more starch, it swells after absorbing water, which may seriously affect the percolation speed, resulting in longer production cycle and higher production cost

Method used

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  • Preparation method of weikang capsule

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] 1. Take 64g of Baiji, 63g of squid octopus, 38g of gallinaceous gold, 1g of egg shell (scrambled) and 13g of Baicao cream, and carry out ultrafine grinding, pass through a 200-300 mesh sieve, and make ultrafine powder for later use;

[0020] 2. Take 63g of frankincense and 15g of myrrh to pulverize with an ultra-low temperature pulverizer, pass through a 180-300 mesh sieve, and make superfine powder for later use;

[0021] 3. Take 64g of Panax notoginseng and 64g of Rhizoma Cyperi, crush them into fine powder, add 65% ethanol, conduct ultrasonic continuous countercurrent extraction for 45min, filter the extract for later use, and repeat the extraction twice. The filtrates were combined and concentrated to a thick paste for subsequent use;

[0022] 4. Put 63g of Radix Astragali and 64g of Radix Paeoniae Alba into an extraction tank, add 8 times the amount of water, decoct and extract for 2 hours, filter the extract for later use, and repeat the extraction three times. T...

Embodiment 2

[0025] 1. Take 64g of Baiji, 63g of squid octopus, 38g of gallinaceous gold, 1g of egg shell (scrambled) and 13g of Baicao cream, and carry out ultrafine grinding, pass through a 200-300 mesh sieve, and make ultrafine powder for later use;

[0026] 2. Take 63g of frankincense and 15g of myrrh to pulverize with an ultra-low temperature pulverizer, pass through a 180-300 mesh sieve, and make superfine powder for later use;

[0027] 3. Take 64g of Panax notoginseng and 64g of Cyperus cyperi, crush them into fine powder, add 75% ethanol, conduct ultrasonic continuous countercurrent extraction for 60min, filter the extract for later use, and repeat the extraction twice. The filtrates were combined and concentrated to a thick paste for subsequent use;

[0028] 4. Put 63g of Radix Astragali and 64g of Radix Paeoniae Alba into an extraction tank, add 8 times the amount of water, decoct and extract for 2 hours, filter the extract for later use, and repeat the extraction three times. T...

Embodiment 3

[0031] 1. Take 64g of Baiji, 63g of squid octopus, 38g of gallinaceous gold, 1g of egg shell (scrambled) and 13g of Baicao cream, and carry out ultrafine grinding, pass through a 200-300 mesh sieve, and make ultrafine powder for later use;

[0032] 2. Take 63g of frankincense and 15g of myrrh to pulverize with an ultra-low temperature pulverizer, pass through a 180-300 mesh sieve, and make superfine powder for later use;

[0033] 3. Take 64g of Panax notoginseng and 64g of Cyperus cyperi, crush them into fine powder, add 85% ethanol, conduct ultrasonic continuous countercurrent extraction for 30min, filter the extract for later use, and repeat the extraction twice. The filtrates were combined and concentrated to a thick paste for subsequent use;

[0034] 4. Put 63g of Radix Astragali and 64g of Radix Paeoniae Alba into an extraction tank, add 8 times the amount of water, decoct and extract for 2 hours, filter the extract for later use, and repeat the extraction three times. T...

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Abstract

A preparation method of a weikang capsule comprises processing steps as follows: (1), 64 g of rhizoma bletillae, 63 g of cuttlebone, 38 g of endothelium corneum gigeriae galli, 1 g of stir-fried egg shells and 13 g of plant soot are taken and subjected to ultrafine grinding for standby; (2), 63 g of frankincense and 15 g of myrrh are taken and ground by an ultralow-temperature grinder for standby; (3) 64 g of pseudo-ginseng and 64 g of rhizoma cyperi are taken and ground into fine powder, ethyl alcohol which accounts for 3-4 times of the quantity of the and has the mass concentration of 65%-85% are added into the fine powder, the fine powder is soaked for 3-4 hours and subjected to ultrasonic continuous countercurrent extraction for 30-60 min, and an extraction liquid is filtered for standby; (4), 63 g of radix astragali and 64 g of radix paeoniae alba are taken and put into an extraction tank, water accounting for 8 times of the quantity of the mixture is added for decoction extraction for two hours, and the extraction liquid is filtered for standby; and (5), the step (3) and the step (4) are combined, thick paste is obtained, the ultrafine powder of the step (1) and the step (2) is added and uniformly mixed, and particles are prepared. According to the method, bioavailability of a human body can be improved, and the production cycle can be shortened while effective ingredients are extracted to the greatest extent.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and in particular relates to a preparation method of Weikang capsules. Background technique [0002] Weikang Capsule is a variety recorded in the Pharmacopoeia of Traditional Chinese Medicine. It has the effects of promoting qi and invigorating the stomach, removing blood stasis and stopping bleeding, regulating acid and relieving pain. For epigastric pain caused by qi stagnation and blood stasis, fixed pain, noisy acid regurgitation, or hematemesis, melena; gastric and duodenal ulcer, chronic gastritis, upper gastrointestinal bleeding, see the above syndromes. Among them, Panax notoginseng promotes blood circulation and removes blood stasis, removes blood stasis and promotes regeneration, reduces swelling and relieves pain; Rhizoma Cyperi volatile oil has central inhibition and antibacterial effects, and its alcohol extract has antipyretic, analgesic, anti-inflammat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K9/48A61J3/07A61P1/00A61K35/56A61K35/54A61K35/37
Inventor 王威刘雪寒张午曲
Owner 沈阳神龙药业有限公司
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