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Traditional Chinese medicine composition for external use and application thereof

A composition and traditional Chinese medicine technology, applied in the directions of drug combinations, pharmaceutical formulations, plant raw materials, etc., can solve the problems of difficult healing or recurrence of wounds, slow formation of granulation tissue, and difficult control of ulcers, and achieve the promotion of skin penetration and efficacy. The effect of reducing the production of sediment and the change of color, and promoting the exertion of the medicinal effect

Inactive Publication Date: 2014-08-27
福州硕博生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, antibiotics, glucocorticoids and other drugs are often used clinically, but if these drugs are used for a long time, they will easily lead to problems such as bacterial resistance and recurrence of the disease, which will make the ulcer difficult to control, or the slow formation of granulation tissue. The wound is difficult to heal or recurs

Method used

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  • Traditional Chinese medicine composition for external use and application thereof
  • Traditional Chinese medicine composition for external use and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Example 1 Traditional Chinese medicine composition and processing method

[0032] Take 40g of Maoyanberry, 30g of Sophorae japonica, and 30g of Scutellaria baicalensis, and concentrate them to 100ml after water extraction and alcohol precipitation, mix with citrate buffer solution with pH=6.6, dilute to 1000ml, add 4g of meglumine, stir to dissolve, spare.

Embodiment 2

[0033] Example 2 Traditional Chinese medicine composition and processing method

[0034] Take 80g of Maoyanberry, 10g of Sophorae japonica, and 10g of Scutellaria baicalensis, after alcohol extraction and water sedimentation, concentrate to 100ml, mix with citrate buffer solution with pH=6.6, dilute to 1000ml, add 8g of meglumine, stir to dissolve, spare.

Embodiment 3

[0035] Example 3 Traditional Chinese medicine composition and processing method

[0036] Take 60g of Maoyanberry, 20g of Sophorae japonica, and 20g of Scutellaria baicalensis, extract with water and ethanol, concentrate to 100ml, mix with citrate buffer solution with pH=6.6, dilute to 1000ml, add 5g of meglumine, stir to dissolve, spare.

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Abstract

The invention discloses a traditional Chinese medicine composition for external use and application thereof. The composition is prepared by processing the following traditional Chinese medicinal raw materials by weight: 40 to 80 parts of Maoyanmei, 10 to 30 parts of sophora flower and 10 to 30 parts of large-flowered skullcap root. The extracts of Maoyanmei, sophora flower and large-flowered skullcap root are added into a buffer solution with a pH value of 5 to 7, then a proper amount of organic alkaline substances are added, and vibration dissolving is carried out so as to obtain the composition. The traditional Chinese medicine composition provided by the invention has higher bacteriostatic, anti-inflammation, pain-relieving and antioxidative effects, can be applied to transdermal drug delivery preparations and cosmetics and exerts treatment effects on acne and angular cheilitis. According to the invention, the application dosage of the composition can be reduced, the composition has small side-effects, generation of precipitates and color changes of the composition can be reduced, and skin permeation of the composition and performance of drug effects are effectively promoted.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine composition for treating acne and angular cheilitis and a preparation method thereof. Background technique [0002] Acne is a common skin disease, and its pathogenesis is mainly related to factors such as abnormal epidermal keratinization, abnormal androgen levels, hyperfunction of sebaceous glands, and overgrowth of Propionibacterium acnes. The incidence of acne is very high. Western epidemiological surveys found that 85% of adolescents suffer from acne, and some patients may leave pigmentation, atrophy or hypertrophic scars, which affect the physical and mental health and quality of life of patients. [0003] Angular cheilitis, commonly known as "rotten corners of the mouth", manifests as flushing, blistering, chapping, erosion, crusting, and desquamation at the corners of the mouth. The patient's mouth is prone to bleedin...

Claims

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Application Information

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IPC IPC(8): A61K36/87A61K8/97A61P17/10A61P17/02A61P1/02
Inventor 黄仁杰王宇平许嵘杨望平
Owner 福州硕博生物技术有限公司
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