Pharmaceutical composition for relieving malaise after chemoradiotherapy and preparation method thereof

A technology of general malaise and composition, applied in the field of pharmacy, can solve the problems of lowering the quality of life of patients, failing to achieve clinical efficacy, psychological burden of patients, etc., achieving protection of myocardial function, safety, no toxic side effects, and reduction of gastrointestinal reactions. Effect

Inactive Publication Date: 2014-09-03
刘洁
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] There is no specific solution for the prevention and treatment of body fatigue caused by radiotherapy and chemotherapy in Western medicine. The main method is to supplement selenium with a reasonable diet. It is advisable to choose nutritious and easy-to-digest foods, such as soft rice, porrid

Method used

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Examples

Experimental program
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Effect test

preparation example Construction

[0075] When the dosage form of the pharmaceutical composition is a capsule, the preparation method includes the following steps:

[0076] Step a: Put the raw medicinal materials into a pulverizer and pass through a 120-mesh fine sieve to make the amount of fine powder that can pass through the 120-mesh sieve reach 30%-40%, and collect the raw material fine powder that passes through the 120-mesh sieve for use;

[0077] Step b. Put the remaining particles after sieving in step a into 5-7 times the amount of ethanol by weight, and heat and reflux for extraction twice, each time for 1 to 2 hours, and then combine the two extracts and let stand still ;

[0078] Step c. Heat and reflux the medicinal residue extracted with ethanol in step b at a ratio of 5 to 7 times the amount of water by weight for 2 times, each time for 1 to 2 hours, and combine the two extracts and let stand;

[0079] Step d. Combine the above two extracts, concentrate the filtrate with a relative density of 50°C to 60°...

Embodiment 1

[0094] Example 1 Capsules

[0095] The embodiment of the present invention provides a pharmaceutical composition for relieving general fatigue after radiotherapy and chemotherapy. The dosage form is a capsule. The weight parts of each raw material are: Codonopsis pilosula 23 parts by weight, Astragalus 22 parts by weight, and 15 parts by weight of Chinese yam. Parts by weight, 15 parts by weight of licorice, 21 parts by weight of jujube, 20 parts by weight of Acanthopanax senticosus, 15 parts by weight of sea buckthorn, 7 parts by weight of Ziheche, 15 parts by weight of sheep red mutton, 8 parts by weight of longan meat, 21 parts by weight of lily, 17 parts by weight of Ophiopogon japonicus, 15 parts by weight of mulberry, 15 parts by weight of floating wheat, 17 parts by weight of schisandra, 15 parts by weight of lotus seeds, 15 parts by weight of Fushen, 15 parts by weight of valerian, 15 parts by weight of Shouwu vine, 15 parts by weight of Gynostemma pentaphyllum , 23 parts...

Embodiment 2

[0102] Example 2 Oral Liquid

[0103] The embodiment of the present invention provides a pharmaceutical composition for relieving general fatigue after radiotherapy and chemotherapy. The dosage form is an oral liquid. The weight parts of the raw materials are: 21 parts by weight of Codonopsis pilosula, 19 parts by weight of Astragalus, 19 parts by weight of Chinese yam Parts by weight, 14 parts by weight of licorice, 21 parts by weight of jujube, 20 parts by weight of Acanthopanax senticosus, 14 parts by weight of sea buckthorn, 12 parts by weight of Ziheche, 15 parts by weight of sheep red mutton, 7 parts by weight of longan meat, 20 parts by weight of lily, 17 parts by weight of Ophiopogon japonicus, 16 parts by weight of mulberry, 16 parts by weight of floating wheat, 17 parts by weight of schisandra, 15 parts by weight of lotus seeds, 15 parts by weight of Fushen, 14 parts by weight of valerian, 14 parts by weight of Shouwu vine, and 14 parts by weight of Gynostemma , 25 part...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for relieving malaise after chemoradiotherapy and a preparation method thereof. The traditional Chinese medicine composition comprises the following medicinal materials: codonopsis pilosula, astragalus membranaceus, Chinese yam, liquorice, Chinese-dates, acanthopanax, sea-buckthorn, human placenta, thellung pimpinella herb, arillus longan, lily, radix ophiopogonis, mulberry, light wheat, schisandra chinensis, lotus seed, poria with hostood, valerian, vine of multiflower knotweed, gynostemma pentaphylla, lucid ganoderma, vicia sativa and cortex albiziae. The pharmaceutical composition disclosed by the invention has the beneficial effects that the pharmaceutical composition is used for benefiting vital energy and nourishing the heart as primary functions, and tonifying the stomach and spleen and sterilizing and detoxifying as auxiliary functions by using the theory of the traditional Chinese medicine in China, the immune system of the organism can be improved, the myocardial function is protected, the gastrointestinal reaction is reduced, the renal toxicity is reduced, the liver is protected, the pathogenic factor resisting abilities, of disinfecting, sterilizing and the like, of the body are improved, and the pharmaceutical composition has the effects of being good in effect, quick to take effect, high in safety and free of toxic and side effects in the aspect of relieving malaise after chemoradiotherapy.

Description

[0001] Technical field [0002] The invention relates to the technical field of pharmacy, in particular to a pharmaceutical composition for relieving general fatigue after radiotherapy and chemotherapy and a preparation method. [0003] Background technique [0004] Radiotherapy and chemotherapy are chemical birth treatments, which are drug promotion treatments for diseases caused by pathogenic microorganisms, parasites, and malignant tumors. Chemotherapy also refers to the application of drugs to treat cancer. These special drugs can kill tumor cells and are sometimes called cytotoxic drugs. [0005] Chemotherapy refers to the drug treatment of diseases caused by pathogenic microorganisms, parasites, and malignant tumors. Chemotherapy is the use of chemicals to treat diseases. Chemotherapy is a treatment that uses chemical drugs to kill tumor cells, inhibit the growth and reproduction of tumor cells, and promote the differentiation of tumor cells. It is a systemic treatment for pr...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P35/00A61P39/00A61P9/00A61P1/16A61P37/04A61K35/50
Inventor 刘洁张淑玲张佩娟
Owner 刘洁
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