Method for detecting hypophosphite in flour and flour improvers
A technology of flour improver and hypophosphite, which is applied in the field of analysis and detection, and achieves the effects of simple pretreatment, high accuracy, and good economic and social benefits
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[0041] (2) preparation of need testing solution
[0042] Take flour or flour improver samples and add ethanol water solution with a volume concentration of 70-80% (preferably 75%), ultrasonically extract (extract 20-30min at normal temperature), centrifuge (800-1200r / min centrifuge 3-5min) and take Supernatant, obtain need testing solution after filtering with microporous membrane (filter element size is 0.22 μm);
[0043] (3) Determination
[0044] Precisely absorb the standard solution and inject it into the ultra-high performance liquid chromatography tandem mass spectrometer for determination, and draw a standard curve according to the test results;
[0045] Precisely absorb the test solution and inject it into an ultra-high performance liquid chromatography tandem mass spectrometer for determination, to obtain final product;
[0046] Wherein the chromatographic conditions are: the chromatographic column is SynergiMAX-RP; the column temperature is room temperature; the m...
Embodiment 1
[0051] The mensuration of embodiment 1 hypophosphite standard substance
[0052] 1. Preparation of hypophosphite standard solution: Accurately weigh 100mg of sodium hypophosphite standard product in a 10mL volumetric flask, dilute to the mark with water, shake well, and prepare a concentration of 10.0mg / mL hypophosphite standard product solution, 4 ℃ and protected from light.
[0053] 2. Chromatography and mass spectrometry conditions
[0054] 1) Chromatographic conditions
[0055] Chromatographic column: SynergiMAX-RP4u250×4.6mm, or equivalent;
[0056] Column temperature: room temperature;
[0057] Mobile phase: acetonitrile: 10mmoL / L ammonium acetate solution = 15: 85 (V / V);
[0058] Flow rate: 0.5mL / min, for isocratic elution;
[0059] 2) Mass spectrometry conditions
[0060] Ion source: electrospray ion source (ESI);
[0061] Scanning method: negative ion scanning;
[0062] Capillary voltage: 0.5kV;
[0063] Cone voltage: 30V;
[0064] Ion source temperature: 15...
Embodiment 2
[0075] Determination of hypophosphite content in negative wheat flour of embodiment 2
[0076] 1. Preparation of test solution
[0077] Take 1g of wheat flour sample, add 20mL of 75% (V / V) ethanol aqueous solution (ethanol: water = 3:1), ultrasonically extract at 20°C for 20min, centrifuge at 1000r / min for 3min, take 1mL of supernatant and filter it with microporous Membrane filtration, the filtrate was tested by ultra-high performance liquid chromatography tandem mass spectrometer.
[0078] 2. Chromatographic conditions
[0079] With embodiment 1.
[0080] 3. Draw a standard curve
[0081] The standard curve of Example 1 was used.
[0082] Four. Determination
[0083] Precisely draw 10 μL of the test solution and inject it into the liquid chromatograph, measure it according to the ultra-high performance liquid chromatography tandem mass spectrometry method, and obtain the ultra high performance liquid chromatography tandem mass spectrogram, as shown in the attached ima...
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