Method for preparing intravascular stent upon 3D (three-dimensional) printing technology

Abstract

The invention discloses a method for preparing an intravascular stent upon the 3D (three-dimensional) printing technology. The method comprises the following steps: firstly establishing a 3D model of the intravascular stent in a computer; inputting data of the established model into corollary equipment of a 3D printer and setting a printing program; bonding a mixed powder material, consisting of stainless steel powder or nickel-titanium powder and stearic acid powder, with a bonder through 3D printing program control to form an intravascular stent blank; performing degreasing, vacuum sintering and cooling treatment on the blank in sequence to obtain the intravascular stent. According to the preparation method, the personalized model can be designed according to the actual requirement of a patient, and the required intravascular stent blank can be rapidly and accurately prepared; the further prepared intravascular stent has a complete surface and has no defects of deformation or cracking and the like; especially, the prepared intravascular stent has no rejection reaction in 24 days in simulated body fluid, is good in biocompatibility and completely meets the medical requirement; the cost for preparing the intravascular stent by a traditional laser cutting method is greatly reduced.

Description

technical field [0001] The invention relates to a method for preparing an intravascular stent based on 3D printing technology, which belongs to the field of medical device preparation. Background technique [0002] Vascular stent technology is a minimally invasive interventional treatment method, which is used to support narrowed and occluded blood vessels in the human body due to disease, and to restore blood circulation. primary means. The processing material of the vascular stent should be corrosion-resistant, have good compatibility with the vessel wall and blood, be fatigue-resistant, and can be clearly visualized under X-rays. At present, the widely used intravascular stent is mainly prepared by tube laser cutting process, but this method is costly, the design of the stent structure is limited, and it is difficult to realize the complex shape of the vascular stent, and the key performance such as accuracy and smoothness cannot be achieved, so it is in clinical practic...

AI Technical Summary

Problems solved by technology

However, the preparation of medical devices generally has relatively high requirements on materials. The materials produced by 3D printing are often due to the selection of different materials, inappropriate binders selected during molding, and poor control of process parameters, which will lead to blanks. Defects such as fuzzy body surface, warping deformation, size deformation, stepped surface, microstructure defects, fragmentation, and mislayering are fatal hazards for the use of 3D printing technology in the manufacture of medical devices

Moreover, due to the shrinkage and deformation of the product during the sintering process, it is difficult to control the dimensional accuracy of the product.

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