Method for preparation of o-nitrobenzoic acid by catalytic oxidation of o-nitrotoluene
A technology of o-nitrobenzoic acid and o-nitrotoluene, applied in the field of catalytic oxidation to prepare o-nitrobenzoic acid, can solve the problems of methanol and benzene solvent toxicity, high solvent toxicity, and equipment corrosion
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Embodiment 1
[0018] In a 1000ml autoclave, add 200ml methanol, 200g o-nitrotoluene, 1.5g catalyst MnO 2 / RuO 4 (MnO 2 with RuO 4 The mass ratio is 1:1), under full stirring, oxygen is introduced. The reaction temperature was maintained at 100°C and the pressure at 0.1 MPa. After 12 hours, the reaction was stopped. Cool to room temperature, release the pressure, filter the catalyst, distill off the solvent methanol under reduced pressure, extract with ether-water, separate phases, wash the organic phase with water, and recover the solvent by distillation to obtain o-nitrobenzoic acid with a yield of 89.1% and a purity of More than 96%. The catalyst after filtering by o-nitro group can be recycled.
Embodiment 2
[0020] In the autoclave of 1000ml, add 200ml ethanol, 200g o-nitrotoluene, 2.0g catalyst MnO 2 / RuO 4 (MnO 2 with RuO 4 The mass ratio is 1.5:1), under full stirring, oxygen is introduced. The reaction temperature was maintained at 140° C. and the pressure at 0.5 MPa. After 10 hours, the reaction was stopped. Cool to room temperature, release the pressure, filter the catalyst, distill off the solvent methanol under reduced pressure, extract with ether-water, separate phases, wash the organic phase with water, and recover the solvent by distillation to obtain o-nitrobenzoic acid with a yield of 92.3% and a purity of More than 96%. The catalyst after filtering by o-nitro group can be recycled.
Embodiment 3
[0022] In a 1000ml autoclave, add 200ml methanol, 30g o-nitrotoluene, 0.5g catalyst MnO 2 / RuO 4 (MnO 2 , RuO 4 The mass ratio is 1:1), under full stirring, oxygen is introduced. The reaction temperature was maintained at 120° C. and the pressure at 1.5 MPa. After 6 hours, the reaction was stopped. Cool to room temperature, release the pressure, filter the catalyst, distill off the solvent methanol under reduced pressure, extract with ether-water, separate phases, wash the organic phase with water, and recover the solvent by distillation to obtain o-nitrobenzoic acid with a yield of 91.7% and a purity of More than 96%. The catalyst after filtering by o-nitro group can be recycled.
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com