Application of class of butenolide compounds in preparation of marine biofouling prevention coating material

A marine biofouling, butenolactone technology, applied in antifouling/underwater coatings, biocide-containing paints, coatings, etc., can solve problems such as low release rate, affecting embryo growth, and destroying ecological balance. , to achieve good lipophilic effect

Active Publication Date: 2015-02-18
SOUTH CHINA SEA INST OF OCEANOLOGY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Subsequent antifouling coatings that dominate the market are copper-containing antifouling coatings with low release rates. However, heavy metal elements will accumulate in the ocean, especially in harbors, resulting in a large number of algae deaths, affecting carp, shrimp, crabs, etc. And the embryonic growth of various molluscs and backpack animals, destroying their blood cells, thereby destroying their ecological balance, so it will eventually be banned

Method used

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  • Application of class of butenolide compounds in preparation of marine biofouling prevention coating material
  • Application of class of butenolide compounds in preparation of marine biofouling prevention coating material
  • Application of class of butenolide compounds in preparation of marine biofouling prevention coating material

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Embodiment 1: the anti-marine macrofouling biological barnacle larva attachment test of the butenolide compound represented by formula (1)-formula (8)

[0017] The activity test model is the attachment inhibition test of barnacles larvae (Barnacles larvae), one of the most commonly used marine fouling biological models in laboratories. Adult barnacles feed on Chaetoceros gracilis Schutt, and culture barnacle nauplii to Venus larva stage in 0.22 μm filtered seawater, with 2 larvae per ml at 28°C. Activity tests were carried out with the resulting Venus stage larvae. Anti-larval settling activity of compounds was determined using 24-well polystyrene plates. The compound butyrolactone V (Formula 1) was dissolved in DMSO and diluted with sterile filtered seawater to obtain solutions of different concentrations (60–140 μg / mL) as test solutions. Add 1mL test solution and 20±2 mature barnacle larvae to each well, set 5 replicate samples for each concentration, and sterile fi...

Embodiment 2

[0020] Embodiment 2: the wild sea siding activity test of the butenolide compound shown in formula (8)

[0021] The field sea hanging board test adopts the traditional anti-fouling biological field sea hanging board test method. 0.2g and 0.4g of the butenolide compound shown in formula (8) were completely dissolved with 1mL of methanol, then fully mixed with 10mL of resin containing 45% polyurethane and spread on dry PVC (10× 10×0.3cm) board, air-dried and hung in the scallop breeding sea area of ​​Daya Bay, Shenzhen (114°32'59 east longitude, 22°40'37 north latitude). The PVC containing 0.2 g of the butenolide compound represented by the formula (8) was regarded as treatment group 1, and the PVC containing 0.4 g of the butenolide compound represented by the formula (8) was regarded as the treatment group 2. Three parallels were set up for each treatment. Take 1mL of methanol and 10mL of resin containing 45%polyurethane and mix them well, then coat the plate as a control. T...

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Abstract

The invention discloses an application of a class of a butenolide compounds in the preparation of a marine biofouling prevention coating material. The butyrol actone V, the aspernolide A, the butyrolactone IV, the aspernolide B, the butyrolactone II, the 4-(4-Hydroxyphenyl)-5-(4-hydroxypheneylmethyl)-2-hydroxyfurane-2-one, the 5,6-dihydropenicillic acid and the 5,6-dihydro-6-hydroxy-penicillic acid, which are provided by the invention, have marine biofouling prevention activity and can be used for preparing the marine biofouling prevention coating material; if the compounds permeate or diffuse into film forming natural resin, polyethylene ethyl acetate copolymer and other polymers such as hydrolyzable, soluble or insoluble resin in an independent or combined way to prepare the marine biofouling prevention coating material, the marine biofouling prevention coating material can release sufficient effective components to a surface to achieve an antifouling function; as the compounds are natural active ingredients, are hard to dissolve in water but easy to dissolve organic solvents such as chloroform, ethyl acetate and methyl alcohol, and have favorable oleophilic properties, the components can be applied to preparing the marine antifouling agents in an independent or combined way and have a favorable application prospect.

Description

Technical field: [0001] The invention belongs to the field of biology, and in particular relates to the application of a class of butenolide compounds in the preparation of anti-marine biofouling coatings. Background technique: [0002] In the historical process of developing and utilizing the ocean, human beings have always been faced with the problem of preventing and eradicating marine organisms. Marine fouling organisms are a general term for various animals, plants and microorganisms that inhabit or attach to ships and various underwater artificial facilities and adversely affect human economic activities. There are more than 4,000 species of marine fouling organisms in the world, and 614 species have been recorded in my country's coastal areas, among which the most important groups are barnacles, algae, hydra, eucalyptus (lime worm), bivalves and sea squirts. Marine fouling organisms attach, grow and even form communities on the surface of various objects such as hull...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C09D5/16
CPCC08K5/1535C08K5/1545C09D5/14C09D5/1625
Inventor 漆淑华农旭华张晓勇徐新亚
Owner SOUTH CHINA SEA INST OF OCEANOLOGY - CHINESE ACAD OF SCI
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