Pharmaceutical composition for treating liver cirrhosis and preparation method of pharmaceutical composition

A technology of composition and medicine, applied in the field of pharmaceutical composition for treating liver cirrhosis and its preparation, capable of solving problems such as decompensation period

Inactive Publication Date: 2015-02-25
张恩荣
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] 2. Decompensation period (generally belongs to Child-Pugh B, C grade)
[0016] (4) Treatment of complications: Because there is no effective and complete treatment for liver cirrhosis, early detection and isolation of patients should be given to active treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] Take 30g black tiger, 30g erythrina, 30g plum, 30g cork, 30g jiubing, 30g longan parasite, 30g sand pear tree parasite, 30g water banyan tree parasite, 20g white back maple, 20g Niu Dali, 20g Wuzhi mountain ginseng, 20g yellow-footed chicken, 20g palmflower, 20g grass buckle, 20g small intestine wind, 20g sea wind rattan, 20g tangerine peel, 20g salvia miltiorrhiza, 20g wrinkled wrinkle, 5g Cyperus cyperi, 5g gynostemma, 5g cypress, add water to extract 2 times, twice The amount of water added is 10 times and 8 times the total weight of the medicinal materials, and the two extraction times are 2 hours and 1 hour respectively. The extracts are combined and filtered. When the filtrate is concentrated to an extract with a relative density of 1.10 at 80 ° C, purified water is added. Until the total weight is 3 times of the total weight of the medical materials, fill it to obtain the mixture of the present invention.

Embodiment 2

[0075] Take 25g of black tiger, 25g of erythrina, 25g of plum, 25g of cork, 25g of jiubing, 25g of longan parasite, 25g of sand pear tree parasite, 25g of water banyan tree parasite, 15g of white back maple, 15g of Niu Dali, 15g of Wuzhi mountain ginseng, Yellow-footed chicken 15g, Pukui 15g, Caokou 15g, Xiaochangfeng 15g, Caulis 15g, Tangerine peel 15g, Salvia miltiorrhiza 15g, Huoxiang 15g, Cyperus cyperi 3g, Gynostemma 3g, Cypress cypress 3g, reflux extraction with 40% ethanol 3 Each time, the amount of ethanol each time is 10 times, 8 times, and 4 times the total amount of medicinal materials, and the extraction time is 3 hours, 2 hours, and 1 hour respectively. The extracts are combined and filtered. When the filtrate is concentrated to 60 ° C, the relative density is 1.25 The extract is added with auxiliary materials such as starch, ethanol and talcum powder to prepare tablets.

Embodiment 3

[0077]Take 35g black tiger, 35g erythrina, 35g plum, 35g cork, 35g jiubing, 35g longan parasite, 35g sand pear tree parasite, 35g water banyan tree parasite, 25g white back maple, 25g Niu Dali, 25g Wuzhi mountain ginseng, 25g yellow-footed chicken, 25g palmflower, 25g grass buckle, 25g small intestine wind, 25g sea wind rattan, 25g tangerine peel, 25g salvia miltiorrhiza, 25g wrinkled wrinkle, 10g Cyperus cyperi, 10g gynostemma, 10g cypress, add water to extract 3 times, add water three times The amount of water is equivalent to 12 times, 8 times, and 6 times of the total weight of the medicinal materials, and the extraction time is 3 hours, 2 hours, and 1 hour respectively. The extracts are combined and filtered. Add ethanol to make the alcohol content 40%, let it stand for 24 hours, filter, the filtrate is concentrated to an extract with a relative density of 1.10 at 70°C, add purified water until the total weight is 3 times the total weight of the medicinal materials, pour ...

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PUM

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Abstract

The invention relates to a pharmaceutical composition for treating liver cirrhosis and a preparation method of the pharmaceutical composition. The pharmaceutical composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: kadsura coccinea, erythrina variegate, radix ilicis asprellae, golden cypress, ovate leaf holly bark, arillus longan parasite, pyrus pyrifolia parasite, water banyan parasite, buddleja asiatica, radix millettiae speciosae, root of arrowleaf abelmoschus, rhizome of perny false fairybells, livistona chinensis, alpinia speciosa, Xiaochangfeng (a medicine for treating hernia), kadsura pepper stem, pericarpium citri reticulatae, salvia miltiorrhiza, cablin potchouli herb, rhizoma cyperi, gynostemma pentaphyllum and herba selaginellae doederleinii. With application of the pharmaceutical composition, various symptoms of patients with the liver cirrhosis can be effectively relieved.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine for treatment, in particular to a pharmaceutical composition for treating liver cirrhosis and a preparation method thereof. Background technique [0002] Liver cirrhosis is a common clinical chronic progressive liver disease, which is diffuse liver damage caused by long-term or repeated effects of one or more causes. In my country, most of them are post-hepatitis cirrhosis, and a small part are alcoholic cirrhosis and schistosome cirrhosis. Histopathologically, extensive liver cell necrosis, nodular regeneration of residual liver cells, connective tissue hyperplasia, and fibrous septum formation lead to structural destruction of hepatic lobules and formation of pseudolobules. The liver gradually deforms and hardens and develops into cirrhosis. In the early stage, there are no obvious symptoms due to the strong compensatory function of the liver. In the later stage, liver function damag...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61P1/16
CPCA61K9/1652A61K9/2059A61K9/4866A61K36/11A61K36/185A61K36/48A61K36/486A61K36/532A61K36/537A61K36/57A61K36/67A61K36/752A61K36/756A61K36/80A61K36/87A61K36/889A61K36/8905A61K36/896A61K36/9062A61K2300/00
Inventor 张恩荣
Owner 张恩荣
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