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Selenium-enriched colla corii asini inulin chewable tablet and preparation method thereof

The technology of chewing tablet and gelatin chrysanthemum is applied in the field of chewing gelatin gelatin powder and its preparation field, which can solve the problems of limiting the use range of gelatin gelatin, inability to take it, blood in the stool, etc., and achieves the effects of lowering blood sugar, being convenient to carry, and improving blood sugar.

Inactive Publication Date: 2015-03-25
YANTAI INST OF COASTAL ZONE RES CHINESE ACAD OF SCI +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the limitations of the existing production process, the newly made donkey-hide gelatin always contains some fire poison, so taking fresh donkey-hide gelatin will cause people to have excessive anger and various poisoning symptoms, causing dry throat and constipation or stool belt Blood and other symptoms
In addition, in order to reconcile the taste of donkey-hide gelatin, it is generally necessary to add a large amount of sucrose or other sugars that can cause blood sugar to rise in the human body, making it impossible for diabetics or people who are sensitive to sugar to take it, which limits the use of donkey-hide gelatin.
At present, donkey-hide gelatin has already appeared in the ranks of health products in various dosage forms such as oral liquid and granules, but there is no donkey-hide gelatin chewable tablet.

Method used

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  • Selenium-enriched colla corii asini inulin chewable tablet and preparation method thereof
  • Selenium-enriched colla corii asini inulin chewable tablet and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0022] The raw materials required for production were dried in a constant temperature drying oven at 40°C for 24 hours, and then placed in a dry environment and sealed for storage for later use. Mix the raw materials evenly according to the ratio of 5 grams of donkey-hide gelatin, 40 grams of inulin, 0.1 grams of organic selenium (the selenium content of the organic selenium: 0.8%), 10 grams of apple powder, 5 grams of xylitol, and 20 grams of pregelatinized starch , spraying ethanol with a volume fraction of 95% into the mixture, the amount of alcohol added is 20% of the total mass of raw materials, and stirred until the particles are formed. Dry the granular product in a drying oven at 25°C for 2 hours. The dried mixture is first passed through a 20-mesh sieve to remove larger agglomerates, and then passed through an 80-mesh sieve to remove ungranulated powder. Add the magnesium stearate of 0.5g in the granule after drying, carry out tabletting after mixing, the selenium-en...

Embodiment 2

[0024] The raw materials required for production were dried in a constant temperature drying oven at 45°C for 24 hours, and then placed in a dry environment and sealed for future use. According to the ratio of 10 grams of donkey-hide gelatin, 35 grams of inulin, 0.2 grams of organic selenium (the selenium content of the organic selenium is 1.2%), 25 grams of lemon powder, 10 grams of mannitol, and 5 grams of lactose, the raw materials are mixed evenly, and added to the mixture. Spraying ethanol with a volume fraction of 95%, the amount of alcohol added is 30% of the total mass of raw materials, and stirred until the particles are formed. The granular product was dried in a drying oven at 30°C for 3 hours. The dried mixture is first passed through a 20-mesh sieve to remove larger agglomerates, and then passed through an 80-mesh sieve to remove ungranulated powder. Add 1g of talcum powder to the dried granules, mix evenly and then press into tablets. The selenium-enriched donke...

Embodiment 3

[0026] The raw materials required for production were dried in a constant temperature drying oven at 50°C for 24 hours, and then placed in a dry environment and sealed for storage for later use. According to the ratio of 15 grams of donkey-hide gelatin, 25 grams of inulin, 0.5 grams of organic selenium, 35 grams of strawberry powder, 20 grams of xylitol, and 15 grams of pregelatinized starch, mix the raw materials evenly, and spray ethanol with a volume fraction of 95% into the mixture , the amount of alcohol added is 25% of the total mass of raw materials, and stirred until the particles are formed. Dry the granular product in a drying oven at 45°C for 4 hours. The dried mixture is first passed through a 20-mesh sieve to remove larger agglomerates, and then passed through an 80-mesh sieve to remove ungranulated powder. Add the magnesium stearate of 2g in the granule after drying, carry out tabletting after mixing, the selenium-enriched donkey-hide gelatin chewable tablet tha...

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Abstract

The invention discloses a selenium-enriched colla corii asini inulin chewable tablet and a preparation method thereof. The selenium-enriched colla corii asini inulin chewable tablet is prepared by the following steps: sequentially pre-treating raw materials; uniformly mixing; granulating; drying; straightening and tabletting by taking organic selenium, colla corii asini and inulin as main effective components which are assisted by a condiment, a filler, a lubricant and the like. The selenium-enriched colla corii asini inulin chewable tablet specifically comprises the following components in percentage by mass: 5-15% of colla corii asini, 25-40% of inulin, 0.1-0.5% of organic selenium (the content of selenium in the organic selenium is 1%), 10-35% of a corrigent, 5-20% of the filler, 5-20% of a sweetening agent and 0.3-2% of a lubricant. The preparation method comprises the following steps: pre-treating the raw materials; granulating; straightening; and tabletting. The selenium-enriched colla corii asini inulin chewable tablet disclosed by the invention has the beneficial effects that (1) the chewable tablet which serves as a common preparation has the advantages of being accurate to meter, good in stability, convenient to carry and eat and the like; (2) not only are the functions of original components retained, but also the deficiency that the raw materials are independently eaten is overcome; and (3) as the raw materials contain se-polysaccharide and inulin, the product disclosed by the invention not only can exert the function of colla corii asini, but also can achieve a better effect of reducing the blood glucose, thereby being beneficial for the diabetes to take.

Description

technical field [0001] The invention relates to a chewable tablet, in particular to a donkey-hide gelatin inulin chewable tablet and a preparation method thereof. Background technique [0002] Donkey-hide gelatin is a solid gelatin made from dried or fresh donkey skin by decocting and concentrating. It is also called "three nourishing treasures" together with ginseng and velvet antler. Donkey-hide gelatin is sweet in taste and flat in nature, and it belongs to the lung, liver and kidney meridians. Donkey-hide gelatin contains 18 kinds of amino acids, 8 of which are essential for the human body. Modern studies have confirmed that donkey-hide gelatin has a good blood-enriching effect on animals with blood deficiency, and its curative effect on the growth rate of hemoglobin and red blood cells is better than that of iron. It has the effect of promoting human immune function and strengthening the body. In addition, donkey-hide gelatin can regulate menstruation and prevent misc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/09A61K35/36A61K9/20A61P7/06A61P37/04A61P15/06A61P25/20A61P3/10A61K31/715A23L29/30A23L33/10A23L33/125A23L33/16
CPCA23V2002/00A23V2200/30A23V2200/32A23V2200/328A23V2250/1626A23V2250/5062
Inventor 衣悦涛刘胜一徐兰兰任世斌任堃
Owner YANTAI INST OF COASTAL ZONE RES CHINESE ACAD OF SCI