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A plant extract compound with antibacterial, anti-inflammation, hemostasis and pain relief and its application

A plant extract and compound technology, applied in the field of oral health care products, can solve the problems of lack of oral products of traditional Chinese medicine extracts, achieve good market development prospects, definite effect, and the effect of inhibiting dental caries

Active Publication Date: 2016-11-30
弘海融合发展深圳有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] To sum up, there is still a shortage of traditional Chinese medicine extract oral products with clear ingredients, clear functions, and outstanding effects, and there is a lot of room for development

Method used

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  • A plant extract compound with antibacterial, anti-inflammation, hemostasis and pain relief and its application
  • A plant extract compound with antibacterial, anti-inflammation, hemostasis and pain relief and its application
  • A plant extract compound with antibacterial, anti-inflammation, hemostasis and pain relief and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Embodiment 1: the preparation method of nude flower purple pearl extract

[0018] Decoct the whole plant of Zizhu nudiflora with water three times (mass ratio of material to water: 1:10), 2 hours each for the first and second times, and 1 hour for the third time, combine the decoctions, filter, concentrate the filtrate and heat at 70-80 degrees Celsius When the relative density is 1.20 extract, after cooling, slowly add ethanol so that the mass percentage of ethanol is 60%, fully stir, let stand for 12 hours, filter the supernatant, adjust the pH value to 6.0-7.0 with sodium hydroxide solution, Add an appropriate amount of 75% ethanol water solution to the residue, stir evenly, let it stand for 12 hours, filter, combine the ethanol solution, recover the ethanol to obtain the Nadiflora extract, freeze-dry to obtain the Nadiflora extract.

Embodiment 2

[0019] Embodiment 2: the preparation method of tea flavonoids

[0020] Green tea is pulverized, soaked in 80% ethanol aqueous solution for 2 hours, filtered to remove tea dregs, concentrated ethanol to obtain extract, 10% sodium chloride solution is added to the extract, allowed to stand for 12 hours, and the precipitate is removed to obtain filtrate. Adjust the pH value of the filtrate to 4-5, and catalyze the reaction at a temperature of 60 degrees Celsius for 2 hours. The reaction solution after the catalytic reaction is extracted with ethyl acetate at a volume ratio of 1:1, extracted three times, the extracts are combined, concentrated and freeze-dried to obtain the total catechins, ie theaflavones.

Embodiment 3

[0021] Embodiment 3: the preparation of plant extract compound

[0022] The plant extract compound of the present invention is composed of the Auranthus nudica extract and the tea flavonoids of Example 2, and the Auranthus nudica extract and the tea flavonoids are composed according to a mass ratio of 1-5:5-1, According to the above mass ratio, after uniformly mixing the extract of Auranthus nudiflora and tea flavonoids, the plant extract compound of the present invention with the functions of antibacterial, anti-inflammatory, hemostasis, pain relief, deodorization and refreshing oral cavity can be obtained.

[0023] According to the mass ratio of the Auranthus nudica extract of Example 1 and the tea flavonoids of Example 2 in a mass ratio of 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1 :4 and 1:5 are evenly mixed to obtain the plant extract compound of the present invention with antibacterial, anti-inflammatory, hemostasis, pain relief, deodorization and refreshing oral cavity in dif...

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Abstract

The invention discloses a plant extract compound capable of inhibiting bacteria, resisting inflammation, stopping bleeding and relieving pain and an application of the plant extract compound. The plant extract compound is prepared from callicarpa nudiflora extract and flavonoids according to a mass ratio of (1-5) to (5-1). The callicarpa nudiflora extract has the functions of resisting inflammation, inhibiting bacteria, resisting viruses, stopping blood, relieving pain, adjusting immunity, removing free radicals and resisting oxidation; the callicarpa nudiflora extract has an effect of resisting most of pathogenic bacteria to different extents. The flavonoids have the effects of inhibiting dental caries, effectively degrading bacterial endotoxin, and preventing and treating periodontitis. The antibacterial, anti-inflammatory, analgesia and hemostasis experiments prove that the plant extract compound is exact in therapeutic effect, natural, healthy and easy to produce; the use effect of the plant extract compound is obviously superior to that of the components of oral cavity cleaning products. Therefore, the plant extract compound has a good market development prospect.

Description

Technical field: [0001] The invention belongs to the field of oral health products, and in particular relates to a plant extract compound with antibacterial, anti-inflammatory, hemostatic and pain-relieving properties and an application thereof. Background technique: [0002] The material life of the current society has been very rich. While people's consumption level has improved, their health concept has become increasingly strong, especially oral problems, which have attracted much attention. The so-called disease enters through the mouth. In other words, the oral cavity is the gateway to human health. A good oral environment can not only protect the body from the invasion of germs, but also create a relaxed and pleasant conversation atmosphere in interpersonal communication, leaving a good impression on the other party. At present, people's demands for oral hygiene are mainly manifested in three aspects: first, suitable toothpaste, especially natural plant toothpaste, ca...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/85A61P7/04A61P1/02A61K9/12A61K8/97A61K8/02A61Q11/00A61P31/02A61P31/04A61K31/353
CPCA61K31/353A61K36/82A61K36/85A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/55A61K2300/00
Inventor 文佳颖易博杨涛陶琳
Owner 弘海融合发展深圳有限公司
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