Anti-coagulant polyester hemodialysis membrane and preparation method thereof
A technology of hemodialysis and anticoagulation, applied in semipermeable membrane separation, chemical instruments and methods, membrane technology, etc., can solve the problems of non-dialysis membrane materials, poor retention rate of middle molecules and bovine albumin, etc., and achieve anticoagulation Good blood effect, improve anticoagulant phenomenon, high biocompatibility effect
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Embodiment 1
[0021] A polyester anticoagulant hemodialysis membrane, the dialysis membrane is a hollow fiber membrane prepared by using phospholipidized polyester polymer as the main membrane material, and adding a small amount of chitosan nanoparticles, including the following components in parts by mass : 25 parts of polyethylene terephthalate, 12 parts of glyceryl phosphate, 10 parts of tetrahydrofuran, 3 parts of trimethylamine, 2 parts of chitosan nanoparticles and 22 parts of dimethylacetamide.
[0022] According to the preparation method provided by the present invention, the polyester anticoagulant hemodialysis membrane is prepared, and the dry-wet method is adopted. The preparation steps are as follows:
[0023] (1) Put polyester and phospholipid into THF and stir evenly, add catalyst, react in water bath for 15 hours, part of polyester and phospholipid react to obtain phospholipidized polyester polymer;
[0024] (2) Prepare the spinning solution, put the above mixture into the sp...
Embodiment 2
[0030] A polyester anticoagulant hemodialysis membrane, the dialysis membrane is a hollow fiber membrane prepared by using phospholipidized polyester polymer as the main membrane material, and adding a small amount of chitosan nanoparticles, including the following components in parts by mass : 33 parts of polybutylene terephthalate, 15 parts of glyceryl phosphate, 15 parts of tetrahydrofuran, 4 parts of trimethylamine, 4 parts of chitosan nanoparticles and 30 parts of dimethylacetamide.
[0031] According to the preparation method provided by the present invention, the polyester anticoagulant hemodialysis membrane is prepared, and the dry-wet method is adopted. The preparation steps are as follows:
[0032] (1) Put polyester and phospholipid into THF and stir evenly, add catalyst, react in water bath for 15 hours, part of polyester and phospholipid react to obtain phospholipidized polyester polymer;
[0033] (2) Prepare the spinning solution, put the above mixture into the sp...
Embodiment 3
[0039] A polyester anticoagulant hemodialysis membrane, the dialysis membrane is a hollow fiber membrane prepared by using phospholipidized polyester polymer as the main membrane material, and adding a small amount of chitosan nanoparticles, including the following components in parts by mass : 39 parts of polyarylate, 16 parts of glycerol phosphate, 22 parts of tetrahydrofuran, 5 parts of trimethylamine, 6 parts of chitosan nanoparticles and 36 parts of dimethylacetamide.
[0040] According to the preparation method provided by the present invention, the polyester anticoagulant hemodialysis membrane is prepared, and the dry-wet method is adopted. The preparation steps are as follows:
[0041] (1) Put the polyester and phospholipid into tetrahydrofuran and stir evenly, add a catalyst, and react in a water bath for 18 hours. Part of the polyester and phospholipid react to obtain a phospholipidized polyester polymer;
[0042](2) Prepare the spinning solution, put the above mixtu...
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