External traditional Chinese medicine composition with efficacies of scavenging free radical and removing redness and swelling as well as preparation and preparation method of external traditional Chinese medicine composition

A technology of free radicals and compositions, applied in the field of external use of traditional Chinese medicine compositions, can solve the problems of little research on damage, and achieve the effects of simple preparation method, easy acceptance, inhibition and reduction of capillary permeability

Active Publication Date: 2015-04-29
NORTHEAST AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are various types of skin care products on the market, most of which are mainly moisturizing and whitenin...

Method used

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  • External traditional Chinese medicine composition with efficacies of scavenging free radical and removing redness and swelling as well as preparation and preparation method of external traditional Chinese medicine composition
  • External traditional Chinese medicine composition with efficacies of scavenging free radical and removing redness and swelling as well as preparation and preparation method of external traditional Chinese medicine composition
  • External traditional Chinese medicine composition with efficacies of scavenging free radical and removing redness and swelling as well as preparation and preparation method of external traditional Chinese medicine composition

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] The preparation of embodiment 1 this Chinese medicine composition

[0056] (1) Pass through a 40-mesh sieve after the following raw materials are pulverized, weigh and mix according to the weight ratio;

[0057] Agarwood 20g, honeysuckle 10g, Chuanqiong 10g, wild chrysanthemum 10g, amber 5g.

[0058] (2) Soak the bulk drug in 70% ethanol at room temperature for 2 hours, the mass volume ratio of the bulk drug to ethanol g / ml is 1:15; ultrasonically extract at 50°C for 50 minutes with frequency 50kHz, power 160W;

[0059] (3) filtering the extract obtained in step (2) through a 100 mesh filter plate to obtain the filtrate;

[0060] (4) Concentrate the filtrate to 20% of the original volume to obtain a concentrate; add 1,3-butanediol to the concentrate, stir and dissolve at 50°C for 1 hour, and the mass ratio of the concentrate to 1,3-butanediol is 1 : 1; sterilized at 90°C for 20 minutes after filtering with a filter plate, to obtain.

Embodiment 2

[0061] The preparation of embodiment 2 this Chinese medicine composition

[0062] (1) Pass through a 40-mesh sieve after the following raw materials are pulverized, weigh and mix according to the weight ratio;

[0063] Agarwood 18g, honeysuckle 8g, Chuanqiong 12g, wild chrysanthemum 12g, amber 3g.

[0064] (2) Soak the crude drug in 60% ethanol at room temperature for 4 hours, the mass volume ratio of the crude drug to ethanol g / ml is 1:18; use ultrasonic wave with a frequency of 40 kHz and a power of 100 W for 40 minutes at 40°C;

[0065] (3) 200 meshes of the extract obtained in step (2) are filtered, and the filter plate is finely filtered to obtain the filtrate;

[0066] (4) Concentrate the filtrate to 30% of the original volume to obtain a concentrated solution; add 1,3-butanediol to the concentrated solution, stir and dissolve at 50°C for 1 hour, and the mass ratio of the concentrated solution to 1,3-butanediol is 1 : 2; sterilized at 85° C. for 30 minutes after filter...

Embodiment 3

[0067] Embodiment 3 The preparation of this Chinese medicine composition

[0068] (1) Pass through a 40-mesh sieve after the following raw materials are pulverized, weigh and mix according to the weight ratio;

[0069] Agarwood 24g, honeysuckle 12g, Chuanqiong 8g, wild chrysanthemum 8g, amber 8g.

[0070] (2) Soak the crude drug in 80% ethanol at room temperature for 3 hours, the mass volume ratio of the crude drug to ethanol g / ml is 1:12; use ultrasonic waves with a frequency of 30 kHz and a power of 120 W for 45 minutes at 60°C;

[0071] (3) 200 meshes of the extract obtained in step (2) are filtered, and the filter plate is finely filtered to obtain the filtrate;

[0072] (4) Concentrate the filtrate to 25% of the original volume to obtain a concentrate; add 1,3-butanediol to the concentrate, stir and dissolve at 50°C for 1 hour, and the mass ratio of the concentrate to 1,3-butanediol is 1 : 1.5; sterilized at 85° C. for 30 minutes after filtering through a filter plate. ...

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Abstract

The invention discloses an external traditional Chinese medicine composition with the efficacies of scavenging free radical and removing redness and swelling. The external traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 18-24 parts of agilawood, 8-12 parts of honeysuckle, 8-12 parts of sichuan lovage rhizome, 8-12 parts of wild chrysanthemum flower and 3-8 parts of amber. An experiment proves that the external traditional Chinese medicine composition is safe to skin and free of thrill, has the efficacies of effectively removing DPPH free radical, superoxide anion free radical and hydroxyl free radical, and can also play a long-lasting hydrating role; the external traditional Chinese medicine composition are easily available in raw material and simple and convenient in preparation method and environmentally friendly, is easily accepted by people and has good application and market prospects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for external use, in particular to a traditional Chinese medicine composition for external use with the effect of scavenging free radicals and removing redness and swelling, and a traditional Chinese medicine preparation prepared from the skin care composition. Background technique [0002] In recent years, the smog index in most parts of China has increased significantly, and the impact of smog on health has attracted social attention. The inhalation of smog will affect people's respiratory system, cause oxidative stress or verification reaction in people with low resistance, and also cause immune system disorders. Although people can alleviate the adverse effects of the above situation by wearing anti-smog masks. However, the damage of smog to people's skin is often not taken seriously and cannot be avoided through effective means. Smog contains a lot of dust, sulfide, and nitrogen...

Claims

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Application Information

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IPC IPC(8): A61K36/835A61P17/18A61P17/04A61K8/97A61Q19/00A61K35/10
Inventor 李富恒王领刘增兵李楠丁
Owner NORTHEAST AGRICULTURAL UNIVERSITY
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