Calcium phosphate bioactive ceramic and preparation method thereof

A calcium phosphate biological and active ceramic technology, applied in medical science, prosthesis, etc., can solve the problems of stainless steel fatigue, low strength, poor plastic stability, etc., and achieve the effect of promoting bone growth and good mechanical stability.

Inactive Publication Date: 2015-07-29
SUZHOU VIVOTIDE BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Biological hard tissue substitute materials were first used body bones and animal bones, and later developed to use stainless steel and plast

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0021] Example 1:

[0022] A calcium phosphate bioactive ceramic, including the following parts by mass:

[0023] 50 parts of tetracalcium phosphate, 3 parts of nano titanium oxide, 3 parts of aluminum silicate fiber, 2 parts of zinc oxide, 10 parts of tricalcium phosphate and 6 parts of calcium oxide.

[0024] To prepare calcium phosphate bioactive ceramics according to the preparation method provided by the present invention, the steps are as follows:

[0025] (1) Weighing: accurately weigh each component;

[0026] (2) Ball mill: Mix the components together and put them in a ball mill for grinding and mixing;

[0027] (3) Cold press molding: the mixed powder is compressed by a 60T press;

[0028] (4) Put the molded powder into the mold and calcine at a high temperature, the temperature is 1150℃, the pressure is 500MPa, and the time is 4h;

[0029] (5) After calcination, take it out after cooling to obtain block calcium phosphate bioactive ceramics.

[0030] The obtained block calcium phos...

Example Embodiment

[0031] Example 2:

[0032] A calcium phosphate bioactive ceramic, including the following parts by mass:

[0033] 75 parts of tetracalcium phosphate, 9 parts of nano titanium oxide, 8 parts of aluminum silicate fiber, 5 parts of zinc oxide, 22 parts of tricalcium phosphate and 10 parts of calcium oxide.

[0034] To prepare calcium phosphate bioactive ceramics according to the preparation method provided by the present invention, the steps are as follows:

[0035] (1) Weighing: accurately weigh each component;

[0036] (2) Ball mill: Mix the components together and put them in a ball mill for grinding and mixing;

[0037] (3) Cold press molding: the mixed powder is compressed by a 60T press;

[0038] (4) Put the molded powder into the mold and calcine at a high temperature, the temperature is 1150℃, the pressure is 500MPa, and the time is 7h;

[0039] (5) After calcination, take it out after cooling to obtain block calcium phosphate bioactive ceramics.

[0040] The obtained block calcium pho...

Example Embodiment

[0041] Example 3:

[0042] A calcium phosphate bioactive ceramic, including the following parts by mass:

[0043] 70 parts of tetracalcium phosphate, 7 parts of nano titanium oxide, 6 parts of aluminum silicate fiber, 4 parts of zinc oxide, 20 parts of tricalcium phosphate and 9 parts of calcium oxide.

[0044] To prepare calcium phosphate bioactive ceramics according to the preparation method provided by the present invention, the steps are as follows:

[0045] (1) Weighing: accurately weigh each component;

[0046] (2) Ball mill: Mix the components together and put them in a ball mill for grinding and mixing;

[0047] (3) Cold press molding: the mixed powder is compressed by a 60T press;

[0048] (4) Put the molded powder into the mold and calcine at a high temperature, the temperature is 1100℃, the pressure is 460MPa, and the time is 6h;

[0049] (5) After calcination, take it out after cooling to obtain block calcium phosphate bioactive ceramics.

[0050] The obtained block calcium phos...

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Abstract

The invention discloses a calcium phosphate bioactive ceramic and a preparation method thereof, and relates to the field of biomaterials. The calcium phosphate bioactive ceramic is prepared from the following ingredients in parts by weight: 50-75 parts of tetracalcium phosphate, 3-9 parts of titanium oxide, 3-8 parts of aluminum silicate fiber, 2-5 parts of zinc oxide, 10-22 parts of tertiary calcium phosphate and 6-10 parts of calcium oxide. The preparation method comprises the following steps: (1) weighing; (2) ball milling; (3) cold press molding; (4) high-temperature calcining; (5) cooling. The calcium phosphate bioactive ceramic has certain mechanical stability and better biocompatibility; meanwhile, the calcium phosphate bioactive ceramic can slowly dissolve and release the bone nutrition elements of calcium and phosphorus, promotes bone growth, and is an ideal bone renovating biomaterial.

Description

technical field [0001] The invention belongs to the field of biomaterials, in particular to a calcium phosphate bioactive ceramic and a preparation method of the bioceramic. Background technique [0002] With the development of material science and technology, biomaterials have become one of the important research directions in the field of biomedicine because of their special properties of repairing, replacing and regenerating body tissues. Biological hard tissue substitute materials were first used body bones and animal bones, and later developed to use stainless steel and plastics. Due to the problems of dissolution, corrosion and fatigue of stainless steel, plastics have problems of poor stability and low strength. Therefore, the bottleneck in the development of biomaterials is caused. The emergence of bioceramics has improved the shortage of existing alternative materials. Because of its many advantages, bioceramics has broad development prospects. [0003] Calcium pho...

Claims

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Application Information

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IPC IPC(8): C04B35/447C04B35/622A61L27/12A61L27/02A61L27/54
Inventor 邱东成刘乐峰郭玉芹
Owner SUZHOU VIVOTIDE BIOTECH
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