Preparation method of granular preparation for treating hypertensive heart disease

A technology of granules and high blood pressure, which is applied in the field of pharmacy, can solve the problems of adverse economic effects, high uncertainty, and high recurrence rate, and achieve the effect of rich drug sources, easy acceptance, and simple production

Inactive Publication Date: 2015-09-23
济南高天机械设备有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Appropriately cooperate with digitalis inotropic drugs and diuretics, but because the disease mainly occurs in middle-aged and elderly people, the uncertainty in the treatment process is relatively high, the risk is high, and the recurrence rate after treatment is high. Both physical and psychological effects will cause relatively large adverse effects. Based on this, a method for preparing granules for treating hypertensive heart disease is provided, which can treat both the symptoms and root causes of hypertensive heart disease.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] The weight-to-number ratio of each raw medicinal material in the medicine is: 10 parts of ginkgo leaves, 5 parts of amethyst, 5 parts of pig heart, 6 parts of Eucommia, 10 parts of mulberry, 15 parts of longan, 15 parts of Wujincao, and 10 parts of Atractylodes macrocephala , 10 parts of orchid, 5 parts of Xiangru, 5 parts of Yulong whip, 5 parts of Codonopsis, 10 parts of cinnamon, 5 parts of banana flower, 5 parts of velvet antler, 10 parts of Radix Ophiopogon, 10 parts of Schisandra, 5 parts of Astragalus, 5 parts of Caulis Spatholobus share;

[0045] The dosage form of described medicine is granule, and its specific preparation process is:

[0046] Step 1: Mix the raw medicinal materials according to the stated ratio, grind them into granules, pass through a 120-200 mesh sieve, place them in a decoction casserole, add water twice the weight of the mixture and soak for 10-20 minutes;

[0047] Step 2: Heat to boiling, reduce the heat to simmer for fifteen minutes, an...

Embodiment 2

[0052] The weight-to-number ratio of each raw medicinal material in the medicine is: 30 parts of ginkgo leaves, 25 parts of amethyst, 30 parts of pig heart, 18 parts of Eucommia, 25 parts of Sangjisheng, 35 parts of longan, 28 parts of Wujincao, and 28 parts of Atractylodes macrocephala , 30 parts of orchid, 25 parts of Xiangru, 18 parts of Yulong whip, 20 parts of Codonopsis, 30 parts of cinnamon, 25 parts of plantain flower, 18 parts of velvet antler, 30 parts of Ophiopogon japonicus, 25 parts of schisandra, 22 parts of astragalus, 26 parts of Milletanus share.

[0053] The dosage form of this medicine is granule, and its preparation method is the same as embodiment 1.

Embodiment 3

[0055] The ratio of parts by weight of each raw medicinal material in the medicine is: 15 parts of ginkgo leaves, 10 parts of amethyst, 10 parts of pig heart, 8 parts of Eucommia, 15 parts of mulberry, 20 parts of longan, 18 parts of Wujincao, 15 parts of Atractylodes macrocephala , 15 parts of orchid, 10 parts of Xiangru, 8 parts of Yulong whip, 8 parts of Codonopsis, 15 parts of cinnamon, 10 parts of plantain flower, 8 parts of velvet antler, 15 parts of Ophiopogon japonicus, 12 parts of Schisandra chinensis, 10 parts of astragalus, and 10 parts of Caulis Spatholobus share.

[0056] The dosage form of this medicine is granule, and its preparation method is the same as embodiment 1.

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PUM

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Abstract

The invention discloses a preparation method of a granular preparation for treating a hypertensive heart disease. The granular preparation comprises the following raw material medicines: gingko leaves, amethyst, pig heart, eucommia ulmoides, taxillus sutchuenensis, longan, alpine swertia, rhizoma atractylodis macrocephalae, bark of stewartia sinensis, glossogyne tenuifolia, stachytarpheta jamaicensis, codonopsis pilosula, cinnamon, japanese banana flower, corn cervi pantotrichum, radix ophiopogonis, schisandra chinensis, astragalus membranaceus and caulis spatholobi. The dosage form is a granular preparation which is prepared from the following specific processes: mixing, grinding, boiling after soaking, and separating out a first-time decoction liquid; then, separating out the second-time decoction liquid by adopting the same method; mixing the two decoction liquids, performing centrifugal separation, drying, and adding sucrose powder and beta-cyclodextrin to prepare the mixture into the granular preparation. Compared with the prior art, the prepared granular preparation has the efficacies of promoting blood circulation to remove blood stasis, eliminating phlegm, descending turbid, calming the liver, suppressing yang, removing stasis, reducing phlegm, removing heat from the liver, nourishing kidney, nourishing liver, tonifying qi, nourishing yin, dehumidifying, removing turbidness, and supplementing benefits, and is highly targeted.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a method for preparing granules for treating hypertensive heart disease. Background technique [0002] Hypertensive heart disease is an organic heart disease formed due to the long-term elevation of blood pressure that gradually increases the load on the left ventricle, and the left ventricle gradually thickens and expands due to compensation. Hypertensive heart disease generally occurs several years to more than ten years after the onset of hypertension, and can be divided into a cardiac function compensation period and a cardiac function decompensation period according to changes in cardiac function. In the period of cardiac function compensation, the patient may have no obvious symptoms, but in the period of cardiac function decompensation, the symptoms of left heart failure will gradually appear. Symptoms gradually aggravated, and the above-mentioned symptoms showed paroxys...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K9/16A61P9/12A61P9/00A61K35/32A61K35/34A61K33/14
Inventor 柏焕焕
Owner 济南高天机械设备有限公司
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