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Application of traditional Chinese medicine composition in preparation of medicines for improving lipid metabolism

A technology of composition and traditional Chinese medicine, which is applied in the application field of traditional Chinese medicine composition, and can solve the problem of single adverse reaction of the action target

Inactive Publication Date: 2015-09-30
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, Western medicine has many methods for treating diabetes and its complications, but its target is single, and adverse reactions often occur

Method used

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  • Application of traditional Chinese medicine composition in preparation of medicines for improving lipid metabolism
  • Application of traditional Chinese medicine composition in preparation of medicines for improving lipid metabolism
  • Application of traditional Chinese medicine composition in preparation of medicines for improving lipid metabolism

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0094] The proportioning of this Chinese medicine composition is as follows:

[0095] 102 g ginseng, 136 g sealwort, 68 g fried atractylodes with bran, 56 g flavescens, 83 g Poria cocos, 136 g Ophiopogon japonicus, 83 g Radix Polygoni Multiflori, 102 g rehmannia glutinosa, 136 g dogwood, 56 g beptis chinensis, 56 g Peilan, litchi 136 g of core, 56 g of Sunburned Epimedium, 68 g of Anemarrhena, 89 g of Salvia, 136 g of Pueraria root, and 83 g of Digupi.

[0096] The preparation process of this Chinese medicine composition granule is:

[0097] a. Weigh Chinese medicinal materials according to the prescription amount, cleanly select and break;

[0098] b. Add 6 times the amount of water to Peilan and Cangzhu, extract the volatile oil, the oil extraction time is 5 hours, collect the volatile oil in another device, filter the aqueous solution for later use, and discard the residue;

[0099] c. After impregnating Cornus officinalis with 7 times the amount of 75% ethanol for 24 hours...

Embodiment 2

[0105] The raw material drug formula is:

[0106] Ginseng 50 g, Polygonatum 180 g, Atractylodes 40 g, Sophora flavescens 58 g, Poria cocos 40 g, Ophiopogon japonicus 180 g, Polygonum multiflorum 40 g, Rehmannia glutinosa 110 g, Cornus officinalis 60 g, Coptidis 58 g, Perrin 35 g, Lychee core 140 g , Epimedium 35 g, Anemarrhena 90 g, Salvia miltiorrhiza 40 g, Pueraria 180 g, Digupi 40 g.

[0107] The preparation method is:

[0108] a. Weigh Chinese herbal medicines according to the prescription amount, cleanly select and break them;

[0109] b. Add 5 times the amount of water to Peilan and Cangzhu to extract the volatile oil. The oil extraction time is 3 hours. The volatile oil is collected in another device, and the aqueous solution is filtered for later use, and the residue is discarded;

[0110] c. After impregnating Cornus officinalis with 5 times the amount of 50% ethanol for 12 hours, perform percolation, collect the percolation liquid, recover ethanol, and concentrate ...

Embodiment 3

[0116] The raw material drug formula is:

[0117] Ginseng 150g, Polygonatum 60g, Atractylodes 90g, Sophora flavescens 30g, Poria cocos 90g, Ophiopogon japonicus 60g, Polygonum multiflorum 90g, Rehmannia glutinosa 60g, Cornus officinalis 180g, Coptidis 30g, Perrin 58g, Lychee core 80g , Epimedium 58 g, Anemarrhena 35 g, Salvia miltiorrhiza 110 g, Pueraria 56 g, Digupi 90 g.

[0118] The preparation method is:

[0119] a. Weigh Chinese herbal medicines according to the prescription amount, cleanly select and break them;

[0120] b. Add 9 times the amount of water to Peilan and Cangzhu to extract the volatile oil. The oil extraction time is 6 hours. The volatile oil is collected in another device, and the aqueous solution is filtered for later use, and the residue is discarded;

[0121] c. After impregnating Cornus officinalis with 9 times the amount of 90% ethanol for 48 hours, perform percolation, collect the percolation liquid, recover ethanol, and concentrate it into a thic...

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Abstract

The invention discloses an application of a traditional Chinese medicine composition in preparation of medicines for improving lipid metabolism, and belongs to the field of traditional Chinese medicine applications. The traditional Chinese medicine composition is prepared from ginseng, rhizoma polygonati, rhizoma atractylodis, radix sophorae flavescentis, radix ophiopogonis, rehmannia, polygonum multiflorum, dogwood, poria cocos, herba eupatorii, coptis chinensis and rhizoma anemarrhenae. The traditional Chinese medicine composition disclosed by the invention is capable of improving the lipid metabolism of kidneys by inhibiting SREBP-1 / ACC / FASN (sterol regulatory element binding protein-1 / activated calcium carbonate / fatty acid synthetase).

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to the application of traditional Chinese medicine compositions. Background technique [0002] Metabolic syndrome, also called insulin resistance syndrome, is a pattern of multiple metabolic risk factors occurring together. The so-called insulin resistance refers to the insensitivity of the body to insulin. In the early stage, the blood sugar can be maintained by increasing the secretion of insulin. In the late stage, the blood sugar rises and various complications occur due to the failure of pancreatic islet function. [0003] With the improvement of human living standards and changes in lifestyle, the incidence of metabolic syndrome is increasing year by year. The main features of metabolic syndrome include obesity, insulin resistance, hypertension, abnormal blood lipid metabolism, hyperglycemia, etc. Insulin resistance, as a common pathological basis, is ...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P3/10A61P3/06A61P13/12
Inventor 贾振华魏聪高怀林常丽萍袁国强孙颖庞洁付靖何双凤
Owner HEBEI YILING MEDICINE INST
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