Unlock instant, AI-driven research and patent intelligence for your innovation.

Method for preparing monodisperse superparamagnetic iron oxide nanoparticles by pyrolysis of ferrocene

A superparamagnetic iron oxide, nanoparticle technology, applied in iron oxide/iron hydroxide, nanotechnology, nanotechnology and other directions, can solve the problems of no iron oxide magnetic nanoparticle research, high reaction system requirements, etc., to achieve good magnetic properties Ability, small size effect

Active Publication Date: 2017-10-31
NORTHWESTERN POLYTECHNICAL UNIV
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The iron sources used in the preparation of iron oxide by thermal decomposition in the existing published literature are mainly iron oleate, iron acetylacetonate and iron pentacarbonyl. There is no research on the preparation of iron oxide magnetic nanoparticles by thermal decomposition of ferrocene, and The current pyrolysis method has high requirements on the reaction system, the solvent must be degassed in advance, and the entire reaction process also needs to be carried out under the protection of an inert gas to ensure that the system is anhydrous and oxygen-free

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for preparing monodisperse superparamagnetic iron oxide nanoparticles by pyrolysis of ferrocene
  • Method for preparing monodisperse superparamagnetic iron oxide nanoparticles by pyrolysis of ferrocene

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1: Preparation of superparamagnetic monodisperse nanoparticles by thermal decomposition of ferrocene

[0022] Disperse 0.74g of ferrocene in 20g of octadecene, then add 0.57g of oleic acid, pour it into a three-necked flask with a thermometer and a condenser after dispersing, raise the temperature to 95°C, keep it for 10min, and then increase the temperature at 3.3°C / min The heating rate was raised to 320°C and kept for 3h. When the temperature was lowered to room temperature after the reaction, the product was poured out, and the product was washed 5 times with a mixed solvent of n-hexane and ethanol with a volume ratio of 1:3 to obtain monodisperse superparamagnetic nanoparticles, and finally the product was dispersed in chloroform for storage.

Embodiment 2

[0023] Example 2: Preparation of superparamagnetic monodisperse nanoparticles by thermal decomposition of ferrocene

[0024] Disperse 1.48g of ferrocene in 20g of eicosene, then add 0.57g of oleic acid, pour it into a three-necked flask with a thermometer and a condenser after dispersing, raise the temperature to 90°C, keep it for 20min, and then increase the temperature at 3.3°C / min The heating rate was raised to 330°C and kept for 5h. When the temperature was lowered to room temperature after the reaction, the product was poured out, and the product was washed 5 times with a mixed solvent of n-hexane and ethanol with a volume ratio of 1:3 to obtain monodisperse superparamagnetic nanoparticles, and finally the product was dispersed in chloroform for storage.

Embodiment 3

[0025] Example 3: Preparation of superparamagnetic monodisperse nanoparticles by thermal decomposition of ferrocene

[0026] Disperse 1.48g of ferrocene in 40g of octadecene, then add 6.84g of oleic acid, pour it into a three-necked flask with a thermometer and a condenser after dispersing, raise the temperature to 90°C, keep it for 20min, and then increase the temperature at 3.3°C / min The heating rate was raised to 320°C and kept for 1h. When the reaction is completed and the temperature is lowered to room temperature, the product is poured out, and the product is washed 5 times with a mixed solvent with a volume ratio of n-hexane and ethanol of 1:3 to obtain monodisperse superparamagnetic nanoparticles, and finally the product is dispersed in dichloromethane for preservation .

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle diameteraaaaaaaaaa
Login to View More

Abstract

The invention relates to a method for preparing monodisperse superparamagnetic iron oxide nanoparticles by pyrolyzing ferrocene. Ferrocene is used as an iron source, dispersed in a high-boiling solvent, and a surfactant is added without inert gas protection. After the reaction, let the system cool down naturally, wash the product fully with a solvent, remove unreacted raw materials, high boiling point solvents and surfactants, and obtain monodisperse superparamagnetic small nanoparticles. The advantage of the method of the present invention is that the iron source does not need to be prepared in advance, and the pyrolysis reaction process does not require inert gas protection, and the prepared magnetic nanoparticles are monodisperse, superparamagnetic, and have good magnetic properties, and the specific saturation magnetization reaches 43 emu / g, with a small size and a particle size of 6-10 nm, it can be widely used in biomedical fields such as biomagnetic separation, magnetically targeted drug release, magnetic resonance imaging, and biomagnetic labeling.

Description

technical field [0001] The invention relates to a method for preparing superparamagnetic iron oxide nanoparticles, in particular to a method for preparing monodisperse superparamagnetic iron oxide nanoparticles by pyrolyzing ferrocene. Background technique [0002] Magnetic nanoparticles are currently a research hotspot in the field of functionalized nanomaterials. Because of their unique magnetic responsiveness, they can be controlled by directional operation through an external magnetic field, which is conducive to the simplification and automation of the reaction process. Therefore, they are widely used in the biological field, such as Bioseparation, targeted drug release, biomagnetic separation, biomagnetic labeling, magnetic resonance imaging and magnetic recording of biochips, etc. Existing methods for preparing iron oxide magnetic nanoparticles mainly include solvothermal method, co-precipitation method, pyrolysis method and the like. Among them, the size and shape o...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C01G49/02B82Y30/00
Inventor 张秋禹贾向坤范新龙张宝亮张和鹏
Owner NORTHWESTERN POLYTECHNICAL UNIV