Calcium alginate composite medical surgical dressing and preparation method thereof

A technology of calcium alginate and sodium alginate, applied in dressings, viscous dressings, medical science, etc., can solve the problems of poor mechanical properties and poor absorption properties, achieve good absorption capacity, prolong action time, and durable and stable antibacterial effect Effect

Inactive Publication Date: 2016-02-03
GUANGDONG TAIBAO MEDICAL SCI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Most dressings made of natural materials have good absorption, good biocompatibility and biological activity, but poor mechanical properties
Synthetic polymer materials have good insulation performance and good mechanical strength, but their absorption performance is worse than that of natural materials

Method used

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  • Calcium alginate composite medical surgical dressing and preparation method thereof
  • Calcium alginate composite medical surgical dressing and preparation method thereof
  • Calcium alginate composite medical surgical dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A calcium alginate composite medical dressing, which is composed of an absorbent core layer, a contact surface layer and a composite gel coating; the absorbent core layer is an adhesive layer, and the described contact surface layer is made of chitosan Fiber and activated carbon fiber are blended, and the composite gel coating is composed of the following components in parts by weight: 2 parts of sodium alginate, 0.5 part of medical glycerin, 3 parts of low molecular weight chitosan, 0.5 part of borneol, purified 94 parts of water, the molecular weight of the low molecular weight chitosan is 5000Da, the degree of deacetylation is 70%~85%, and the purity of the medical glycerin is greater than 99.8%. Chitosan fiber has good antibacterial and antibacterial properties, and the hollow and porous structure of activated carbon fiber makes it have good adsorption properties. Combined with the composite gel coating, it can achieve antibacterial, moisturizing, and hemostatic and ...

Embodiment 2

[0030] A calcium alginate composite medical dressing, which is composed of an absorbent core layer, a contact surface layer and a composite gel coating; the absorbent core layer is an adhesive layer, and the described contact surface layer is made of chitosan Fiber and activated carbon fiber are blended, and the composite gel coating is composed of the following components in parts by weight: 3 parts of sodium alginate, 0.8 part of medical glycerin, 2 parts of low molecular weight chitosan, 0.8 part of borneol, purified 93.4 parts of water, the molecular weight of the low molecular weight chitosan is 8000Da, the degree of deacetylation is 70%~85%, and the purity of the medical glycerin is greater than 99.8%. Chitosan fiber has good antibacterial and antibacterial properties, and the hollow and porous structure of activated carbon fiber makes it have good adsorption properties. Combined with the composite gel coating, it can achieve antibacterial, moisturizing, and hemostatic an...

Embodiment 3

[0033] A calcium alginate composite medical dressing, which is composed of an absorbent core layer, a contact surface layer and a composite gel coating; the absorbent core layer is an adhesive layer, and the described contact surface layer is made of chitosan Fiber and activated carbon fiber are blended, and the composite gel coating is composed of the following components in parts by weight: 3.5 parts of sodium alginate, 1 part of medical glycerin, 4 parts of low molecular weight chitosan, 1 part of borneol, purified 90.5 parts of water, the molecular weight of the low molecular weight chitosan is 10000Da, the degree of deacetylation is 70%~85%, and the purity of the medical glycerin is greater than 99.8%. Chitosan fiber has good antibacterial and antibacterial properties, and the hollow and porous structure of activated carbon fiber makes it have good adsorption properties. Combined with the composite gel coating, it can achieve antibacterial, moisturizing, and hemostatic and a...

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Abstract

The invention belongs to the technical field of high-molecular medical biomaterials and relates to a calcium alginate composite medical surgical dressing and a preparation method thereof. The calcium alginate composite medical surgical dressing comprises an absorption core layer, a contact surface layer and a composite gel coating. The absorption core layer is a glue layer. The contact surface layer comprises chitosan fibers and active carbon fibers by blending. The composite gel coating comprises, by weight, 2-4 parts of sodium alginate, 0.5-1 part of medical glycerin, 2-4 parts of low molecular weight chitosan, 0.5-1 part of borneol and 80-100 parts of purified water. The medical surgical dressing prepared from the natural material and the synthetic high-molecular material has good absorbency, good biocompatibility, good biological activity and good mechanical properties.

Description

technical field [0001] The invention belongs to the technical field of polymer medical biomaterials, and in particular relates to a calcium alginate composite medical dressing and a preparation method thereof. Background technique [0002] As a covering for wounds, medical dressings can replace damaged skin to act as a temporary barrier during wound healing, avoid or control wound infection, and provide an environment conducive to wound healing. With the aging population and the increase of chronic ulcerative wounds, the market value of medical dressings is also becoming more and more important. In 1962, the British Winter proposed the "moist wound healing theory", that is, wounds heal faster in a moist environment than in a dry environment, which made a breakthrough in people's understanding of the wound healing process. [0003] Medical dressings can be divided into traditional dressings, biological dressings and synthetic dressings according to their materials. Among th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/42A61L15/18A61L15/46A61L15/44A61F13/02
Inventor 卢亢陈锦涛陈妃奇
Owner GUANGDONG TAIBAO MEDICAL SCI TECH
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