Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Temperature sensitive type polyion liquid gel and preparation method thereof

A technology of polyionic liquid and ionic liquid, which is applied in the field of temperature-responsive polyionic liquid gel and its preparation, can solve the problems that have not been reported in the research, and achieve the effect of broadening the application field

Inactive Publication Date: 2016-02-03
TIANJIN POLYTECHNIC UNIV
View PDF0 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the application research of polyionic liquids has achieved preliminary results in polymer catalysts, polymer electrolytes, gas adsorption / separation materials, etc., but the research on biomaterials in the field of tissue engineering has not been reported yet.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] (1) Preparation of ionic liquid

[0023] Weigh glycine (Gly) and choline (Ch) respectively, dissolve each in 5ml of distilled water, Gly:Ch=1.05mol:1mol, slowly add the choline solution to the glycine solution with a constant pressure dropping funnel at 3°C, and stir magnetically Reaction for 48 hours; after the reaction was completed, water was removed by rotary evaporation at 60°C, and then excess ethanol was poured into the above reaction system to remove unreacted glycine; the reaction product was vacuum-dried at 50°C to remove residual ethanol and water to obtain pure choline-glycine (Ch-Gly) ionic liquid.

[0024] (2) Preparation of vinyl ionic liquid monomer

[0025] Weigh acrylic acid (AAc), dissolve in 10ml distilled water, add N-hydroxysuccinimide (NHS) and 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC), at room temperature After magnetic stirring for 2 hours, add choline-glycine (Ch-Gly) ionic liquid to continue the reaction for 24 hours, AAc: Ch-Gly:...

Embodiment 2

[0029] (1) Preparation of ionic liquid

[0030] Weigh glycine (Gly) and choline (Ch) respectively, dissolve each in 5ml distilled water, Gly:Ch=1mol:1mol, slowly add the choline solution to the glycine solution with a constant pressure dropping funnel at 3°C, and magnetically stir the reaction 48h; after the reaction was completed, the water was removed by rotary evaporation at 60°C, and then excess ethanol was poured into the above reaction system to remove unreacted glycine; the reaction product was vacuum-dried at 50°C to remove residual ethanol and water to obtain pure Choline-glycine (Ch-Gly) ionic liquid.

[0031] (2) Preparation of vinyl ionic liquid monomer

[0032] Weigh acrylic acid (AAc), dissolve in 10ml distilled water, add N-hydroxysuccinimide (NHS) and 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC), at room temperature After magnetic stirring for 2 hours, add choline-glycine (Ch-Gly) ionic liquid to continue the reaction for 24 hours, AAc: Ch-Gly: EDC: N...

Embodiment 3

[0036] (1) Preparation of ionic liquid

[0037] Weigh glycine (Gly) and choline (Ch) respectively, dissolve each in 5ml distilled water, Gly:Ch=2mol:1mol, slowly add the choline solution to the glycine solution with a constant pressure dropping funnel at 3°C, and magnetically stir the reaction 48h; after the reaction was completed, the water was removed by rotary evaporation at 60°C, and then excess ethanol was poured into the above reaction system to remove unreacted glycine; the reaction product was vacuum-dried at 50°C to remove residual ethanol and water to obtain pure Choline-glycine (Ch-Gly) ionic liquid.

[0038] (2) Preparation of vinyl ionic liquid monomer

[0039] Weigh acrylic acid (AAc), dissolve in 10ml distilled water, add N-hydroxysuccinimide (NHS) and 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC), at room temperature After magnetic stirring for 2 hours, add choline-glycine (Ch-Gly) ionic liquid to continue the reaction for 24 hours, AAc: Ch-Gly: EDC: N...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses temperature sensitive type polyion liquid gel and a preparation method thereof, relates to the field of high polymer materials, and particularly relates to temperature responsive polyion liquid gel and a preparation method thereof. The gel can be prepared by the following method: forming ion liquid by glycine of good biocompatibility and choline, and forming vinyl choline-glycine ion liquid monomer by modifying the ion liquid through acrylic acid, and then preparing the temperature sensitive type polyion liquid gel by free radical polymerization with a temperature sensitive material N-isopropyl acrylamide (NIPAAm), taking N,N-methylenebisacrylamide (MBAA) as a cross-linking agent, and potassium persulfate as an initiator. The gel is applied to damage-free desorption of cells.

Description

technical field [0001] The invention relates to the field of polymer materials, in particular to a temperature-responsive polyionic liquid gel and a preparation method thereof. Background technique [0002] In recent years, with the rise of green chemistry, the research on "green solvent"-ionic liquids has set off a global upsurge. The United States, Europe, Japan, etc. have included ionic liquids in their national strategic science and technology plans. Polyionic liquids are the product of the cross-combination of ionic liquids and polymer science. They have both the excellent properties of ionic liquids and polymers, and show the incomparable advantages of small molecule ionic liquids. Related research is gradually arousing people's widespread interest. However, compared with small-molecule ionic liquids, the research on polyionic liquids is not mature enough, and its types are far less than small-molecule ionic liquids. Ionic liquids are of great scientific significance....

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C08J3/075C08F220/36C08F220/54C08F222/38
Inventor 贺晓凌赵宇新金镇栗苏宇刘晓魏东盛
Owner TIANJIN POLYTECHNIC UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com