22 results about "Glycine solution" patented technology

The invention relates to the technical field of metal amino acid chelate preparation, and discloses high-bioavailability magnesium glycinate and a preparation method thereof.The method comprises the steps that a glycine solution and a magnesium salt solution are mixed, the initial pH value is adjusted to be within the alkaline range, and a low-polarity organic phase is added to construct a two-phase solvent system; dynamically adjusting the pH value of the reaction system by stages, and sequentially inducing amino and carboxyl of glycine to chelate magnesium ions step by step to form a chelate; and blending the chelated product with a chitosan-sodium alginate composite carrier, and carrying out spray drying to obtain magnesium glycinate particles. The molar ratio of magnesium ions to glycine in the chelating structure of magnesium glycinate is 1: 3. Through the synergistic effect of dynamic pH regulation and a two-phase solvent system, directional synthesis of the magnesium glycinate 1: 3 high-coordination chelate is achieved, the bioavailability and the targeted slow release performance are remarkably improved by combining a composite carrier nano embedding technology, and meanwhile, the process is efficient and environmentally friendly.

The invention provides a woven nerve conduit with piezoelectric performance and a preparation method and application thereof, and belongs to the field of nerve conduits.The preparation method comprises the steps that degummed silk is soaked in a dopamine hydrochloride solution, sodium hydroxide is added to adjust the pH value, and stirring is conducted to obtain polydopamine modified degummed silk; dispersing the polydopamine modified degummed silk, EDOT and FeCl3. 6H2O in an ethanol solution, stirring, centrifuging, washing and drying to obtain PEDOT modified degummed silk; the degummed silk modified by PEDOT is used as weaving yarn, and a nerve conduit skeleton is woven through a three-dimensional weaving technology; preparing a glycine solution, crystallizing and grinding to obtain beta-type glycine; pLLA particles are dispersed in hexafluoroisopropanol to be dissolved, beta-type glycine is added to obtain a PLLA-coated Gly solution, a PLLA-coated Gly fiber membrane is prepared on the surface of a nerve conduit skeleton through electrostatic spinning, and the woven nerve conduit with the piezoelectric property is obtained. The novel nerve conduit is developed by combining the three-dimensional weaving technology and the piezoelectric material, and a better solution is provided for nerve restoration.

The invention provides a Tl poisoning SCR catalyst in-situ regeneration and Tl resource recovery method, and belongs to the field of waste SCR catalyst recovery. The method comprises the following steps: putting a Tl-poisoned SCR catalyst into a glycine solution, and carrying out solid-liquid separation to obtain a thallium leaching solution and a regenerated SCR catalyst; and then, carrying out thallium precipitation treatment on the thallium leachate, and carrying out solid-liquid separation to obtain thallium-containing precipitates. According to the method, the Tl is selectively extracted from the catalyst by utilizing the specific coordination effect of the glycine and the Tl, and the extracted Tl is recovered while the activity of the SCR catalyst is recovered, so that waste recycling is realized, and the environmental risk is reduced.

The invention belongs to the technical field of pharmaceutical chemicals, and particularly relates to a method for preparing guanidinoacetic acid from glycine mother liquor. Based on a glycine-cyanamide method, a glycine solution containing iminodiacetic acid is used as one of reaction raw materials. When the method is used for preparing the guanidinoacetic acid, the glycine mother liquor can be directly used for preparing the guanidinoacetic acid, so that the mother liquor is directly treated, the separation step of the glycine mother liquor is omitted, and the process is simplified. Moreover, the method has an unexpected technical effect on the improvement of the yield of the guanidinoacetic acid, and the yield of the guanidinoacetic acid is improved by 6.2-6.4% compared with the prior art.

The utility model relates to an on-line monitor and system for evaluating the operation efficiency of a chlorine dioxide generator, a water sample detection module and a data analysis module are arranged in a body, and the water sample detection module is electrically connected with the data analysis module; the water sample detection module comprises a chlorine dioxide detection unit, a free chlorine detection unit and a plurality of linear peristaltic pumps; the chlorine dioxide and free chlorine detection unit is provided with a dilution tank, a detection tank, a reference tank and a spectrophotometer; the water sample detection module is provided with a buffer solution bottle, a DPD solution bottle and a glycine solution bottle which are used for containing the buffer solution, the DPD solution and the glycine solution respectively, and each solution bottle is connected with the corresponding linear peristaltic pump through a hose. The monitor disclosed by the utility model has two modes of health monitoring and abnormity diagnosis, and can continuously track and record the operation efficiency of the chlorine dioxide generator; the operation efficiency of the chlorine dioxide generator can be rapidly analyzed, problems and risks can be identified, an alarm is given, and the safety and stability of the disinfection process are improved.

The invention provides a method for producing food or feed-grade glycine by using mixed crystals of glycine and salt. The method comprises the following steps: S1, dissolving the mixed crystals of glycine and salt in water; s2, performing electrodialysis on the solution, and separating out a salt solution and a glycine aqueous solution; s3, the glycine aqueous solution is subjected to resin impurity removal, and a first-stage purified glycine solution is obtained; s4, performing membrane filtration on the first-stage purified glycine solution to obtain a second-stage purified glycine solution; and S5, continuously concentrating the second-stage purified glycine solution to obtain food or feed-grade glycine. The method for preparing glycine has the advantages of high recovery ratio, low cost, high yield and high purity, and glycine in the material can be purified to reach a food grade.

The invention relates to the technical field of piezoelectric devices, in particular to a preparation method and device of beta-glycine nanocrystals, a piezoelectric composite material and application. The preparation method of the beta-glycine nanocrystal comprises the following steps: injecting a glycine solution into an ultrasonic atomization nozzle, spraying the glycine solution by the ultrasonic atomization nozzle, and depositing the glycine solution on a heating receiving platform to obtain the beta-glycine nanocrystal, and a potential difference exists between the ultrasonic atomization nozzle and the heating receiving platform. According to the method, the beta-glycine nanocrystals with relatively high purity and uniform crystal size can be formed by combining ultrasonic atomization and electrostatic deposition, so that the problem that the beta-glycine crystals are relatively difficult to form is solved.

The present invention relates to the technical field of resin preparation, and in particular to a preparation method and application of an ionic liquid-loaded resin. The method comprises the following steps: S1, pretreating a chloromethylated polystyrene resin; S2, preparing a glycine solution; and S3, preparing the ionic liquid-loaded resin. The present invention enhances the active sites of the resin and improves the reaction efficiency of the resin with glycine by pretreating the chloromethylated polystyrene resin. The glycine ionic liquid-loaded resin is used to purify phosphoric acid, with a high recovery rate, avoiding emulsification, reducing solvent loss, being environmentally friendly, and having excellent recyclability. The prepared ionic liquid-loaded resin has good stability and reusability, thereby extending the service life of the material. The process is simple, easy to implement automated control, and improves production efficiency and sustainability.

The present application discloses a method for synthesizing creatine monohydrate from glycine, which includes mixing formaldehyde with an acid solution to obtain an acidic solution, and adjusting the pH of the acidic solution to 3 to 5; reacting the glycine solution with the acidic solution to obtain a reaction solution; reacting the reaction solution with a cyanamide solution to obtain a creatine reaction solution; and performing post-treatment on the creatine reaction solution to obtain creatine monohydrate. In the present application, high-purity creatine monohydrate is obtained under the environment of a low-concentration reaction solution. Compared with the prior art, the steps are simple, thus simplifying the process of synthesizing creatine monohydrate from glycine. Moreover, in this method, the yield of creatine monohydrate is greater than 70%, and the highest yield can reach 83%, improving the yield of creatine monohydrate.

The invention relates to a method for electrocatalytically synthesizing glycine based on block foamed silver and a separation and purification method thereof, an ultralight foamed silver block is used as a catalytic electrode, the purpose of efficiently electrocatalytically synthesizing glycine is achieved, the reaction conversion rate within 2 hours reaches 99%, the catalytic efficiency is greatly improved, and the method is suitable for industrial production. And after the reaction, the solution only contains glycine and sulfuric acid electrolyte, so that convenience is provided for subsequent separation and purification. Inorganic salt in the obtained acidic glycine solution can be removed through sodium type cation exchange resin, glycine is purified, and high-purity and high-crystallinity glycine powder is obtained through freeze drying. According to the method, the purposes of efficiently synthesizing the glycine and extracting the high-purity glycine powder by using the simple catalyst are achieved, and the synthesis and purification efficiency of the glycine product can be effectively improved.

The invention belongs to the technical field of guanidinoacetic acid, and particularly relates to a granulation method of guanidinoacetic acid and guanidinoacetic acid particles. A glycine solution with a mass concentration of 20% to 40% and a binder are mixed to prepare a mixed solution A, wherein the mass concentration of the binder in the mixed solution A is 1% to 5%; sodium hydroxide is added to the mixed solution A, and the mixture is heated to dissolve to obtain a clear solution B; a cyanamide solution is dripped into the clear solution B to obtain a reaction solution C after the dripping is completed, wherein the molar ratio of cyanamide to glycine in the cyanamide solution is (0.8 to 1):1; the reaction solution C is cooled to 40 to 50°C and then kept warm for 1 to 2 hours, and then cooled to 10 to 12°C again after the heat preservation, and centrifuged to obtain guanidinoacetic acid particles, wherein the cooling rate is 5°C / h to 10°C / h, and the process of preparing the guanidinoacetic acid particles is short and simple, and does not require the aid of granulation equipment, and has the beneficial effect of reducing costs and increasing efficiency.

Disclosed are a bio-piezoelectric layer manufacturing method, a bio-piezoelectric layer manufactured thereby, a piezoelectric power generation device manufacturing method, and a piezoelectric power generation device manufactured thereby. The present invention comprises the steps of: preparing a glycine solution by mixing a glycine powder and a second solvent into a first solvent; immersing a substrate in the glycine solution; and producing glycine crystals by pulling the substrate from the glycine solution.

This invention belongs to the fields of biomedicine, beauty, and personal care health technology, and discloses an oil-controlling, acne-reducing, and antimicrobial peptide co-amorphous assembly, its preparation method, and applications. The method includes: mixing an octyl glycine solution with an antimicrobial peptide solution, rotary evaporation, and drying to obtain an antimicrobial peptide co-amorphous compound; mixing a cyclodextrin compound with water, adding the antimicrobial peptide co-amorphous compound, heating the reaction, and spray drying to obtain the oil-controlling, acne-reducing, and antimicrobial peptide co-amorphous assembly. The oil-controlling, acne-reducing, and antimicrobial peptide co-amorphous assembly provided by this invention efficiently solubilizes octyl glycine through co-amorphous technology and nano-assembly, improving its solubility and bioavailability; simultaneously optimizing the transdermal absorption of the antimicrobial peptide and achieving targeted accumulation in the dermis; the broad-spectrum antibacterial and oil-controlling effects of octyl glycine can be organically combined with the targeted antibacterial effects of the antimicrobial peptide, providing a new strategy for oily and acne-prone skin care; cyclodextrin inclusion enhances stability; the process is mild, simple, environmentally friendly, and easy to industrialize.

The invention discloses a preparation method of a spherical glycine crystal, which comprises the following steps: cooling a glycine solution with the temperature of 70-80 DEG C and the concentration of 0.47-0.52 g / mL to 20-30 DEG C under the stirring condition with the stirring speed of 700-1200 rpm, and keeping the temperature for 1-4 hours to obtain spherical glycine; when the temperature is reduced to 20 to 30 DEG C, the density of the crystal slurry is 0.27 to 0.32 g / mL. Under the condition that no additive is used, water serves as a solvent for cooling crystallization, the crystallization mode in the crystallization process is changed, optimal control is achieved, the high-quality spherical glycine product with the complete crystal form is developed, and the good application prospect is achieved. The characteristic of a single particle of the obtained spherocrystal is 500-2000 microns, the HS roundness value is 0.91-1, the particle size distribution of the obtained spherocrystal is larger than or equal to 77%, the angle of repose is 29-35 degrees, and the caking rate is 1.11-7.68%.

The present invention relates to the technical field of wastewater treatment, and provides a glycine mother liquor treatment process, which comprises the following steps: adjusting the pH of the glycine mother liquor to 3.5 - 4.5, adding a flocculant, filtering for the first time and the second time, and then performing membrane separation and purification to obtain a glycine solution; the flocculant comprises chitosan, and the addition amount of the flocculant is 0.5% - 1.5% of the mass of the glycine mother liquor. Through the above technical solution, the problems of low purity and low yield of glycine recovered from the glycine mother liquor in the related art are solved.

The invention provides a method for continuously preparing glycine. The method comprises the following steps: S1, introducing an ammonium chloroacetate solution, a urotropine solution and ammonia gas into a reactor with a microchannel to prepare a glycine solution; s2, the glycine solution circularly flows between the reactor and the buffer tank; s3, sequentially cooling, crystallizing, centrifuging and drying the glycine solution in the step S2 to obtain a finished product glycine; and S4, concentrating the mother liquor of the residual glycine solution in the step S3, using the concentrated clear liquor to prepare the ammonium chloroacetate in the step S1, and using the residual mother liquor to prepare the urotropine solution in the step S1 after ammonium chloride is removed. According to the method for continuously preparing the glycine, the problem that the local PH in the reactor is too high can be effectively solved through circulation between the glycine solution buffer tank and the reactor, so that continuous preparation of the glycine is facilitated, a large reaction kettle does not need to be used, and good use safety is achieved.

The application belongs to the field of analysis and detection, and particularly relates to a method for detecting the content of directly absorbed exogenous glycine of microorganisms in soil, which comprises the following steps: firstly, mixing a double-labeled glycine solution with soil, adding sodium laureth sulfate and chloroform for fumigation, then extracting, deriving by hydrocarbonation reaction of ethyl bromoformate, and completing the extraction of glycine in microorganisms after stable layering by using sodium bicarbonate solution; and after the extraction is cracked by a stable isotope ratio mass spectrometer, exogenous glycine and original glycine in microorganisms are distinguished by characteristic ions to be determined. The method can effectively detect the content of directly absorbed exogenous glycine of microorganisms, is simple in operation, strong in specificity, has a good linear relationship, high sensitivity and accuracy, and effectively solves the problem that the content of directly absorbed exogenous glycine of microorganisms cannot be directly quantified. Thus, the direct utilization pathway of soil microorganisms to exogenous amino acid substances is quantitatively judged.

The invention discloses a formula of a leaching agent in preparation of light calcium carbonate by indirect mineralization of carbide slag, belongs to the technical field of production of light calcium carbonate, and aims to solve the problems of large reagent loss, low selectivity and the like of an ammonium salt leaching agent in the prior art. According to the technical scheme, the formula of the leaching agent comprises glycine, cane sugar, sodium citrate, tert-butyl alcohol and water. A two-stage leaching process is adopted, and in the first-stage leaching process, a glycine solution is adopted for leaching carbide slag; in the second-stage leaching, a mixed solution of cane sugar, sodium citrate and tert-butyl alcohol is adopted to leach the first-stage filter residues. According to the method, the total leaching efficiency of calcium is improved through two-stage leaching, a leaching agent is not prone to volatilization, small in loss, recyclable and high in calcium ion leaching selectivity, and high-purity light calcium carbonate can be prepared.

The application belongs to the field of analysis and detection, and particularly relates to a method for detecting the content of directly absorbed exogenous glycine of microorganisms in soil, which comprises the following steps: firstly, mixing a double-labeled glycine solution with soil, adding sodium laureth sulfate and chloroform for fumigation, then extracting, deriving by hydrocarbonation reaction of ethyl bromoformate, and completing the extraction of glycine in microorganisms after stable layering by using sodium bicarbonate solution; and after the extraction is cracked by a stable isotope ratio mass spectrometer, exogenous glycine and original glycine in microorganisms are distinguished by characteristic ions to be determined. The method can effectively detect the content of directly absorbed exogenous glycine of microorganisms, is simple in operation, strong in specificity, has a good linear relationship, high sensitivity and accuracy, and effectively solves the problem that the content of directly absorbed exogenous glycine of microorganisms cannot be directly quantified. Thus, the direct utilization pathway of soil microorganisms to exogenous amino acid substances is quantitatively judged.

The present application relates to a kind of based on block body foam silver electrocatalytic synthesis glycine method and its separation and purification method, the present application with ultra-light foam silver block as catalytic electrode, realize the purpose of efficient electrocatalytic synthesis glycine, reaction conversion rate reaches 99% in 2 hours, greatly improve the catalytic efficiency, and solution only contains glycine and sulfuric acid electrolyte after reaction, provide the convenience for subsequent separation and purification.The obtained acidic glycine solution can remove inorganic salts by sodium cation exchange resin, purify glycine, and then freeze-drying, obtain high-purity high-crystalline glycine powder.The present application realizes the purpose of simple catalyst efficient synthesis glycine and extract high-purity glycine powder, can effectively improve the synthesis and purification efficiency of glycine product.

The invention relates to the technical field of purification of amino acids, and particularly discloses a glycine purification method, which comprises the following steps: S1, preparation of a crude glycine solution: dissolving industrial-grade crude glycine to form the crude glycine solution; s2, phosphate coordination reaction: adding phosphate into the crude glycine solution for reaction to form a stable glycine-phosphate coordination compound precipitate; s3, coordination compound separation: carrying out solid-liquid separation on the reaction system in the step S2 to obtain a glycine-phosphate coordination compound and a supernatant containing impurities, and recovering by-products from the supernatant; s4, dissociation of the coordination compound and purification of glycine: dissolving the glycine-phosphate coordination compound, adjusting the pH value to be far away from an isoelectric point of glycine, filtering, adding an organic extraction agent, separating out an organic phase and a water phase liquid, and evaporating and crystallizing the organic phase to obtain purified glycine; and S5, phosphate recovery and circulation: concentrating the aqueous phase liquid, recovering phosphate, and circulating the phosphate for the coordination reaction in the step S2.

The application discloses a method for detecting deoxy-najinmycin in milk and dairy products. The method comprises the following steps: extracting a sample solution to be derivatized by using an extracting agent, adding a buffer solution and a derivatization reagent to the sample solution to be derivatized to perform derivatization, performing liquid chromatography test on the sample to be tested after the derivatization, and qualitatively and quantitatively determining the sample according to the retention time and external standard method. The content of deoxy-najinmycin in the sample to be tested is obtained according to the test result. The extracting agent is an acetonitrile aqueous solution, the buffer solution is a potassium borate buffer solution, and the derivatization reagent comprises a fluorenylmethyloxycarbonyl chloride acetonitrile solution, a glycine solution and an acetic acid aqueous solution. The precision, repeatability, recovery rate and standard curve linearity of the detection method meet the industry requirements. The method has good extraction effect, high sensitivity, stable and accurate results, and is simple to operate and convenient to popularize.