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Artificial intervertebral disc and manufacturing method thereof

An intervertebral disc and artificial technology, applied in medical science, prostheses, spinal implants, etc., can solve a lot of wear debris, prosthetic loosening, articular surface material wear and other problems

Active Publication Date: 2016-02-10
SHENZHEN LANDO BIOMATERIALS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the development of domestic artificial intervertebral discs mainly faces the following technical challenges: After the intervertebral disc is implanted in the human body, the prosthesis is in the complex mechanical / physiological environment of the human body, the articular surface material is severely worn, a large amount of wear debris is generated, and various wear particles induce inflammation. Cause osteolysis around the prosthesis, and finally the prosthesis loosens, resulting in a serious short life of the prosthesis

Method used

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  • Artificial intervertebral disc and manufacturing method thereof
  • Artificial intervertebral disc and manufacturing method thereof

Examples

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preparation example Construction

[0103] Such as figure 2 As shown, the method for preparing an artificial intervertebral disc in one embodiment, the above-mentioned artificial intervertebral disc can be prepared using the method for preparing an artificial intervertebral disc in this embodiment, and the method for preparing an artificial intervertebral disc includes the following steps:

[0104] Step S310: Mix the reinforcing fiber and polyetheretherketone to obtain a first mixed material.

[0105] In step S310, the polyether ether ketone is implant grade. The particle size of PEEK is less than 40 microns.

[0106] Wherein, the reinforcing fiber is selected from at least one of carbon fiber, glass fiber, graphite fiber, silicon carbide fiber, stainless steel fiber and titanium-based whisker fiber.

[0107] Preferably, the reinforcing fiber has a diameter of 1 nanometer to 50 micrometers and a length of 10 micrometers to 1000 micrometers.

[0108] Preferably, in step S310, the step of mixing the reinforcin...

Embodiment 1

[0167] The artificial intervertebral disc of the present embodiment is prepared as follows:

[0168] (1) According to the mass ratio of 0.1:1, the reinforcing fiber is mixed with the implantation grade polyether ether ketone to obtain the first mixed material, wherein the reinforcing fiber is glass fiber with a diameter of 50 microns and a length of 100 microns. The particle size of ether ether ketone is 30 microns.

[0169] (2) Mix the first additive with implantable polyether ether ketone to obtain the first mixed material, wherein the first additive is two kinds of α-tricalcium phosphate and sodium chloride, and the particle size of α-tricalcium phosphate is The particle size of PEEK is 100 microns, and that of PEEK is 30 microns.

[0170] (3) According to the mass ratio of 0.3:1, the active bone repair material and polyether ether ketone are mixed to obtain the second mixed material, wherein the active bone repair material is α-tricalcium phosphate, the particle size is 1...

Embodiment 2

[0182] The artificial intervertebral disc of the present embodiment is prepared as follows:

[0183] (1) According to the mass ratio of 0.1:1, 0.08:1 and 0.06:1, respectively, the reinforcing fiber is mixed with the implant grade polyetheretherketone to obtain the first mixed material 1, the first mixed material 2 and the first mixed material Material 3, wherein the reinforcing fiber is five kinds of carbon fiber, graphite fiber, silicon carbide fiber, stainless steel fiber and titanium-based whisker fiber, the diameter of the reinforcing fiber is 1 nanometer, the length is 10 microns, and the particle diameter of polyether ether ketone is 20 Microns.

[0184] (2) Mix the first additive with implantable polyether ether ketone to obtain the first mixed material, wherein the first additive is hydroxyapatite, β-tricalcium phosphate, calcium sulfate, bioactive glass and chloride Sodium, hydroxyapatite, beta-tricalcium phosphate, calcium sulfate, and bioactive glass all have a par...

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Abstract

An artificial intervertebral disc comprises a first end plate and a second end plate, wherein the first end plate comprises a first abrasion-resisting layer and a first repairing layer which are stacked, and the first repairing layer comprises a first repairing unit layer and a second repairing unit layer which are stacked. The second end plate comprises a second abrasion-resisting layer and a second repairing layer which are stacked, and the second repairing layer comprises a third repairing unit layer and a fourth repairing unit layer which are stacked. The first abrasion-resisting layer and the second abrasion-resisting layer are both made from a polyether-ether-ketone and reinforcing fiber mixture, the first repairing unit layer and the third repairing unit layer are both made from the mixture of polyether-ether-ketone and a first degradable active bone repairing material, and the second repairing unit layer and the fourth repairing unit layer are both made from the mixture of polyether-ether-ketone and a second degradable active bone repairing material. The artificial intervertebral disc has longer service life after being implanted into a human body. In addition, the invention further provides a manufacturing method of the artificial intervertebral disc.

Description

technical field [0001] The invention belongs to the technical field of biomedical materials, and in particular relates to an artificial intervertebral disc and a preparation method thereof. Background technique [0002] Cervical spondylosis and lumbar spondylosis are spinal disorders caused by degeneration of intervertebral discs. They have become common diseases and high incidences that significantly affect the quality of life of middle-aged and elderly people. Among them, in terms of lumbar spondylosis, the total incidence of lumbar disc herniation has reached 15.2-30%, and the number of patients with lumbar spondylosis in my country has exceeded 200 million, and 80% of adults have a history of low back pain. Clinical statistics show that more than 40% of people over the age of 50 have limited activity of the lumbar spine, 60% of which will develop lumbar spine lesions and compression of the nervous system, and about 10%-15% of patients will eventually develop spinal cord ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/44A61L27/18A61L27/50A61L27/54A61L27/12
Inventor 谭荣伟
Owner SHENZHEN LANDO BIOMATERIALS