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Compositions and their use to treat complications of aneurysmal subarachnoid hemorrhage

A technology of dyes and compounds, applied in the field of dyes for hair dyeing, can solve the problems of limited dyes, and achieve the effects of good light fastness, low-cost level dyeing, and good water solubility

Inactive Publication Date: 2016-02-10
HODOGOYA CHEMICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, there are many cases of mutagenicity positive, and the dyes for hair dyeing with high safety are limited.

Method used

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  • Compositions and their use to treat complications of aneurysmal subarachnoid hemorrhage
  • Compositions and their use to treat complications of aneurysmal subarachnoid hemorrhage
  • Compositions and their use to treat complications of aneurysmal subarachnoid hemorrhage

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0086] As shown in Table 1, as a pH regulator, citric acid·H 2 O1g and citric acid tri-Na 2H 2 O11g was dissolved in ion-exchanged water to produce 1 kg of an aqueous solution (water+pH regulator) of pH 6. To the obtained aqueous solution at pH 6, Yellow 29 as a dye and benzyloxyethoxyethanol as a penetrating agent were blended in the composition shown in Table 2 to prepare a hair dye composition at pH 6. 10 g of the produced hair dye composition was weighed, 1 g of human white hair (100%, Beaulaxcoltd, product code BM-W-A) was added, and it was dyed at 45° C. for 20 minutes. Wash the obtained dyed hair with water (running water at 15-25°C for about 1 minute), soap it under the following soaping conditions, wash it with water (running water at 15-25°C for about 1 minute), and leave it at room temperature (about 20°C). ) under natural drying to obtain test samples. In addition, in the following examples and comparative examples, pH adjustment of the hair dye composition was ...

Embodiment 2

[0106] [Example 2] (shampoo fastness test)

[0107] The test sample of Yellow 29 obtained in Example 1 was subjected to the shampoo fastness test shown below, and the dyeing density (K / Sd) and color difference (ΔE*) before and after the test were measured. The results are shown in Table 4. In addition, in the table|surface, the residual ratio (%) means the ratio of the dyeing density after a test, and the dyeing density before a test.

[0108] [Shampoo fastness test]

[0109] The test samples were subjected to the following (1) shampoo treatment, followed by (2) combing treatment as one operation, and after repeating this operation 5 times, they were naturally dried at room temperature (about 20° C.).

[0110] (1) Shampoo treatment conditions

[0111] Shampoo liquid: 5% sodium lauryl sulfate aqueous solution

[0112] Liquor ratio: 1:10 (relative to the quality of shampoo liquid of 1g of hair coloring quality)

[0113] Processing temperature: 45°C

[0114] Processing time...

Embodiment 3、 Embodiment 4

[0128] According to Table 1, aqueous solutions of pH 5 and pH 7 were produced, and the aqueous solutions of pH 5 and pH 7 were used instead of the aqueous solution of pH 6 to produce a hair dye composition, except that the test was obtained by the same method as in Example 1 (dye: yellow 29). Sample inspection. The dyeing density (K / Sd) and color (L*, a*, b*) of the obtained test sample were determined. The results are shown in Table 5.

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Abstract

The described invention provides a method for treating an interruption of a cerebral artery in a subarachnoid space at risk of interruption caused by brain injury in a mammal, which reduces signs or symptoms of at least one delayed complication associated with brain injury using a flowable sustained release particulate composition.

Description

technical field [0001] The present invention relates to a dye for hair dyeing, a composition for dyeing hair and a method for dyeing hair. More specifically, it relates to a hair-dyeing dye and a hair-dyeing composition containing a cationic dye suitable for dyeing keratin fibers contained in human hair and domestic animal hair, and a hair-dyeing method using the hair-dyeing composition. Background technique [0002] The types of hair dyeing can generally be roughly divided into: by mixing oxidation dyes such as p-phenylenediamine with hydrogen peroxide solution during use, hydrogen peroxide is used to decolorize the melanin in the hair, and at the same time, the oxidation dye is oxidized to develop color. Chemical reaction type (hair dyes, oxidative hair colorants (oxidative hair colorants)); and physical adsorption type (hair dyeing) that dyes hair by physical adsorption of direct dyes such as acid dyes and basic dyes to keratin fibers with positive and negative charges. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/49A61Q5/06C09B23/00
CPCA61K8/492A61Q5/06C07D209/14C09B26/04A61K2800/4322A61Q5/065
Inventor 秋叶光弘铃木健一郎权田通博矶边昌敏
Owner HODOGOYA CHEMICAL CO LTD
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