Described herein is a method of reducing a
sign or symptom of a dermal disorder in a subject in need of treatment for the dermal disorder by topically applying a topical silk
fibroin composition once or more daily to the site of the dermal disorder, wherein the silk
fibroin formulation includes no additional dermal therapeutic agents. Also included are methods of reducing topical
steroid use in in a subject in need of treatment for a dermal disorder.