Docetaxel injection and preparation method thereof
A docetaxel, injection technology, applied in pharmaceutical formulations, oil/fat/wax inactive ingredients, drug combinations, etc., can solve problems such as interference with P-glycoprotein expression, temperature sensitivity, patient death, etc., and achieve stability Good performance, stable active ingredient content, good safety effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0020] Preparation of docetaxel injection: mix 10 g of absolute ethanol and 8 g of glycerin evenly, add 0.2 g of anhydrous citric acid and 0.2 g of tartaric acid to completely dissolve, and stir well; add 1 g of docetaxel, and stir until completely dissolved; add 15g polyoxyethylene ether (35) castor oil and 11g polyoxyethylene ether (40) castor oil, stir and mix well; add 30g polyethylene glycol 300 and 25g polyethylene glycol 400, stir and mix well, you can get Dorsey Taxal injection.
Embodiment 2
[0022] Preparation of docetaxel injection: mix 10g of absolute ethanol and 8g of 1,2-propanediol evenly, add 0.2g of anhydrous citric acid and 0.2g of fumaric acid to dissolve completely, stir well; add 1.5g of docetaxel , stir until completely dissolved; add 15g polyoxyethylene ether (35) castor oil and 11g polyoxyethylene castor oil EL, stir and mix evenly; add 30g polyethylene glycol 300 and 25g polyethylene glycol 400, stir and mix evenly, namely Docetaxel injection is available.
Embodiment 3
[0024] Preparation of docetaxel injection: mix 10 g of absolute ethanol and 8 g of 1,2-propanediol evenly, add 0.2 g of anhydrous citric acid and 0.2 g of maleic acid to dissolve completely, and stir well; add 1.5 g of docetaxel , stir until completely dissolved; add 15g polyoxyethylene ether (35) castor oil and 11g polyoxyethylene castor oil EL, stir and mix evenly; add 40g polyethylene glycol 300 and 15g polyethylene glycol 400, stir and mix evenly, namely Docetaxel injection is available.
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com